| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 7, 2026 | Patel Sanjiv | President and CEO | S | 48,199 | $19.5800 | $943.74K |
| Jul 6, 2026 | Catinazzo Thomas | Chief Financial Officer | S | 17,717 | $18.6900 | $331.13K |
| Jul 6, 2026 | Bergstrom Donald A | President, R&D | S | 8,660 | $18.7100 | $162.03K |
| Jun 30, 2026 | Patel Sanjiv | President and CEO | A | 3,056 | $6.9500 | $21.24K |
| Jun 30, 2026 | Rahmer Peter | See remarks | A | 3,056 | $6.9500 | $21.24K |
| Jun 30, 2026 | Rahmer Peter | See remarks | S | 50,000 | $19.0900 | $954.50K |
| Jun 22, 2026 | Bergstrom Donald A | President, R&D | M | 93,456 | $0.0000 | $0.00 |
| Jun 22, 2026 | Bergstrom Donald A | President, R&D | S | 93,456 | $16.9400 | $1.58M |
| Jun 22, 2026 | Bergstrom Donald A | President, R&D | M | 93,456 | $4.1200 | $385.04K |
| Jun 22, 2026 | Catinazzo Thomas | Chief Financial Officer | M | 51,560 | $0.0000 | $0.00 |
| Jun 22, 2026 | Catinazzo Thomas | Chief Financial Officer | M | 61,563 | $0.0000 | $0.00 |
| Jun 22, 2026 | Catinazzo Thomas | Chief Financial Officer | M | 56,323 | $0.0000 | $0.00 |
| Jun 22, 2026 | Catinazzo Thomas | Chief Financial Officer | S | 51,560 | $16.9700 | $874.97K |
| Jun 22, 2026 | Catinazzo Thomas | Chief Financial Officer | M | 51,560 | $4.4500 | $229.44K |
| Jun 22, 2026 | Catinazzo Thomas | Chief Financial Officer | S | 61,563 | $16.9700 | $1.04M |
| Jun 22, 2026 | Catinazzo Thomas | Chief Financial Officer | M | 61,563 | $5.2200 | $321.36K |
| Jun 22, 2026 | Catinazzo Thomas | Chief Financial Officer | S | 56,323 | $16.9700 | $955.80K |
| Jun 22, 2026 | Catinazzo Thomas | Chief Financial Officer | M | 56,323 | $5.0400 | $283.87K |
| Jun 22, 2026 | Catinazzo Thomas | Chief Financial Officer | S | 17,717 | $17.0100 | $301.37K |
| Jun 9, 2026 | Murcko Mark | Director | A | 32,947 | $0.0000 | $0.00 |
| Jun 9, 2026 | COATS LONNEL | Director | A | 32,947 | $0.0000 | $0.00 |
| Jun 9, 2026 | INGRAM DOUGLAS S | Director | A | 32,947 | $0.0000 | $0.00 |
| Jun 9, 2026 | Borisy Alexis | Director | A | 32,947 | $0.0000 | $0.00 |
| Jun 9, 2026 | Dable Habib J | Director | A | 32,947 | $0.0000 | $0.00 |
| Jun 9, 2026 | HILL LINDA A | Director | A | 32,947 | $0.0000 | $0.00 |
| Jun 9, 2026 | Mazumdar Claire | Director | A | 32,947 | $0.0000 | $0.00 |
| May 14, 2026 | Catinazzo Thomas | Chief Financial Officer | S | 17,717 | $12.8600 | $227.84K |
| Apr 28, 2026 | Bergstrom Donald A | President, R&D | S | 1,490 | $14.7900 | $22.04K |
| Apr 28, 2026 | Rahmer Peter | See remarks | S | 753 | $14.7900 | $11.14K |
| Apr 28, 2026 | Catinazzo Thomas | Chief Financial Officer | S | 972 | $14.7900 | $14.38K |
| Apr 9, 2026 | Catinazzo Thomas | Chief Financial Officer | M | 1,800 | $0.0000 | $0.00 |
| Apr 9, 2026 | Catinazzo Thomas | Chief Financial Officer | S | 1,800 | $15.0000 | $27.00K |
| Apr 9, 2026 | Catinazzo Thomas | Chief Financial Officer | M | 1,800 | $5.2200 | $9.40K |
| Apr 7, 2026 | Catinazzo Thomas | Chief Financial Officer | S | 17,717 | $13.0100 | $230.50K |
| Mar 9, 2026 | Catinazzo Thomas | Chief Financial Officer | S | 17,717 | $10.0600 | $178.23K |
| Jan 28, 2026 | Catinazzo Thomas | Chief Financial Officer | S | 1,695 | $8.4500 | $14.32K |
| Jan 28, 2026 | Bergstrom Donald A | President, R&D | S | 2,686 | $8.4500 | $22.70K |
| Jan 28, 2026 | Rahmer Peter | See remarks | S | 1,354 | $8.4500 | $11.44K |
| Jan 27, 2026 | Catinazzo Thomas | Chief Financial Officer | S | 13,820 | $7.6200 | $105.31K |
| Jan 27, 2026 | Bergstrom Donald A | President, R&D | S | 18,895 | $7.6200 | $143.98K |
| Jan 27, 2026 | Rahmer Peter | See remarks | S | 11,684 | $7.6200 | $89.03K |
| Jan 13, 2026 | Catinazzo Thomas | Chief Financial Officer | A | 400,000 | $0.0000 | $0.00 |
| Jan 13, 2026 | Patel Sanjiv | President and CEO | A | 1,450,000 | $0.0000 | $0.00 |
| Jan 13, 2026 | Bergstrom Donald A | President, R&D | A | 575,000 | $0.0000 | $0.00 |
| Jan 13, 2026 | Rahmer Peter | See remarks | A | 475,000 | $0.0000 | $0.00 |
| Jan 6, 2026 | Patel Sanjiv | President and CEO | S | 43,168 | $7.8200 | $337.57K |
| Dec 31, 2025 | Patel Sanjiv | President and CEO | A | 994 | $2.9900 | $2.97K |
| Dec 31, 2025 | Rahmer Peter | See remarks | A | 994 | $2.9900 | $2.97K |
| Nov 4, 2025 | Dable Habib J | Director | A | 207,931 | $0.0000 | $0.00 |
| Nov 4, 2025 | COATS LONNEL | Director | A | 207,931 | $0.0000 | $0.00 |