First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
BVF INC/ILCIK 0001056807 | 16,001,284 | $298.26M | -3,750,000 | ↓ DEC |
Deep Track Capital, LPCIK 0001856083 | 6,408,863 | $119.46M | +1,798,792 | ↑ INC |
Cormorant Asset Management, LPCIK 0001583977 | 4,480,433 | $83.52M | +125,000 | ↑ INC |
CITADEL ADVISORS LLCCIK 0001423053 | 2,081,728 | $38.80M | -213,562 | ↓ DEC |
MPM BioImpact LLCCIK 0001687078 | 1,811,082 | $33.76M | +1,497,511 | ↑ INC |
Weiss Asset Management LPCIK 0001357550 | 1,708,328 | $31.84M | +1,375,367 | ↑ INC |
Point72 Asset Management, L.P.CIK 0001603466 | 1,368,518 | $25.51M | +596,018 | ↑ INC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 1,208,624 | $22.53M | -25,412 | ↓ DEC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 1,130,233 | $21.07M | +859,568 | ↑ INC |
TWO SIGMA INVESTMENTS, LPCIK 0001179392 | 1,122,312 | $20.92M | +337,501 | ↑ INC |
BALYASNY ASSET MANAGEMENT L.P.CIK 0001218710 | 1,065,610 | $19.86M | -505,461 | ↓ DEC |
BlackRock, Inc.CIK 0002012383 | 1,021,851 | $19.05M | +735,258 | ↑ INC |
Vivo Capital, LLCCIK 0001674712 | 1,000,000 | $18.64M | – | no_change |
JPMORGAN CHASE & COCIK 0000019617 | 1,088,514 | $18.43M | +250,775 | ↑ INC |
Candriam S.C.A.CIK 0001537014 | 818,126 | $15.25M | +683,797 | ↑ INC |
BANK OF AMERICA CORP /DE/CIK 0000070858 | 724,794 | $13.51M | +711,261 | ↑ INC |
MORGAN STANLEYCIK 0000895421 | 614,482 | $11.45M | -430,099 | ↓ DEC |
Holocene Advisors, LPCIK 0001700574 | 600,000 | $11.18M | +411,011 | ↑ INC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 576,092 | $10.74M | -226,630 | ↓ DEC |
JANE STREET GROUP, LLCCIK 0001595888 | 572,525 | $10.67M | -1,148,623 | ↓ DEC |
Jefferies Financial Group Inc.CIK 0000096223 | 500,000 | $9.32M | – | no_change |
GREAT POINT PARTNERS LLCCIK 0001281446 | 500,000 | $9.32M | +221,666 | ↑ INC |
Trexquant Investment LPCIK 0001633445 | 495,336 | $9.23M | +311,017 | ↑ INC |
ADAR1 Capital Management, LLCCIK 0001940272 | 477,137 | $8.89M | +308,642 | ↑ INC |
Casdin Capital, LLCCIK 0001534261 | 450,000 | $8.39M | +450,000 | NEW |
| Filer | Δ Shares | Value |
|---|---|---|
Deep Track Capital, LP↑ INC | +1,798,792 | $119.46M |
MPM BioImpact LLC↑ INC | +1,497,511 | $33.76M |
Weiss Asset Management LP↑ INC | +1,375,367 | $31.84M |
GOLDMAN SACHS GROUP INC↑ INC | +859,568 | $21.07M |
BlackRock, Inc.↑ INC | +735,258 | $19.05M |
BANK OF AMERICA CORP /DE/↑ INC | +711,261 | $13.51M |
Candriam S.C.A.↑ INC | +683,797 | $15.25M |
Point72 Asset Management, L.P.↑ INC | +596,018 | $25.51M |
Casdin Capital, LLCNEW | +450,000 | $8.39M |
Holocene Advisors, LP↑ INC | +411,011 | $11.18M |
| Filer | Δ Shares | Value |
|---|---|---|
BVF INC/IL↓ DEC | -3,750,000 | $298.26M |
JANE STREET GROUP, LLC↓ DEC | -1,148,623 | $10.67M |
Nuveen, LLC↓ DEC | -604,017 | $622.89K |
BALYASNY ASSET MANAGEMENT L.P.↓ DEC | -505,461 | $19.86M |
MORGAN STANLEY↓ DEC | -430,099 | $11.45M |
J. Goldman & Co LP↓ DEC | -332,967 | $2.55M |
UBS Group AG↓ DEC | -235,141 | $72.30K |
MILLENNIUM MANAGEMENT LLC↓ DEC | -226,630 | $10.74M |
CITADEL ADVISORS LLC↓ DEC | -213,562 | $38.80M |
MARSHALL WACE, LLP↓ DEC | -209,778 | $2.08M |