第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
FMR LLCCIK 0000315066 | 10,818,491 | $629.10M | +1,898,241 | ↑ INC |
Avoro Capital Advisors LLCCIK 0001633313 | 5,777,777 | $335.98M | +353,333 | ↑ INC |
BlackRock, Inc.CIK 0002012383 | 5,640,118 | $327.97M | +539,834 | ↑ INC |
WELLINGTON MANAGEMENT GROUP LLPCIK 0000902219 | 4,829,641 | $280.84M | +64,862 | ↑ INC |
DRIEHAUS CAPITAL MANAGEMENT LLCCIK 0000938206 | 4,491,653 | $261.19M | -47,038 | ↓ DEC |
CITADEL ADVISORS LLCCIK 0001423053 | 2,886,390 | $167.84M | +1,456,677 | ↑ INC |
Capital International InvestorsCIK 0001562230 | 2,674,727 | $155.54M | -740,232 | ↓ DEC |
JPMORGAN CHASE & COCIK 0000019617 | 1,923,610 | $106.86M | +429,578 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 1,720,533 | $100.05M | +227,983 | ↑ INC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 1,695,037 | $98.57M | +1,557,918 | ↑ INC |
Affinity Asset Advisors, LLCCIK 0001773195 | 1,675,000 | $97.40M | +425,000 | ↑ INC |
DEERFIELD MANAGEMENT COMPANY, L.P.CIK 0001009258 | 1,615,696 | $93.95M | +1,073,676 | ↑ INC |
Holocene Advisors, LPCIK 0001700574 | 1,518,686 | $88.31M | +236,605 | ↑ INC |
WESTFIELD CAPITAL MANAGEMENT CO LPCIK 0001177719 | 1,401,483 | $81.50M | +174,712 | ↑ INC |
Caligan Partners LPCIK 0001727492 | 1,393,027 | $81.00M | +293,662 | ↑ INC |
BNP Paribas Asset Management Holding S.A.CIK 0001520354 | 1,342,028 | $78.04M | +281,807 | ↑ INC |
BRAIDWELL LPCIK 0001920938 | 1,338,452 | $77.83M | -486,624 | ↓ DEC |
Caption Management, LLCCIK 0001706766 | 1,337,900 | $77.80M | +757,900 | ↑ INC |
JENNISON ASSOCIATES LLCCIK 0000053417 | 1,318,814 | $76.69M | +26,759 | ↑ INC |
Siren, L.L.C.CIK 0002005245 | 1,318,564 | $76.67M | +505,803 | ↑ INC |
Alyeska Investment Group, L.P.CIK 0001453072 | 1,299,469 | $75.56M | +932,236 | ↑ INC |
FRANKLIN RESOURCES INCCIK 0000038777 | 1,280,577 | $74.47M | +522,518 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 1,092,932 | $63.55M | +140,253 | ↑ INC |
ALLIANCEBERNSTEIN L.P.CIK 0001109448 | 1,403,297 | $62.90M | -190,517 | ↓ DEC |
ORBIMED ADVISORS LLCCIK 0001055951 | 1,059,971 | $61.64M | +612,771 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
FMR LLC↑ INC | +1,898,241 | $629.10M |
SUSQUEHANNA INTERNATIONAL GROUP, LLP↑ INC | +1,557,918 | $98.57M |
CITADEL ADVISORS LLC↑ INC | +1,456,677 | $167.84M |
DEERFIELD MANAGEMENT COMPANY, L.P.↑ INC | +1,073,676 | $93.95M |
Alyeska Investment Group, L.P.↑ INC | +932,236 | $75.56M |
T. Rowe Price Investment Management, Inc.↑ INC | +859,408 | $55.36K |
Caption Management, LLC↑ INC | +757,900 | $77.80M |
ORBIMED ADVISORS LLC↑ INC | +612,771 | $61.64M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +543,062 | $31.58M |
BlackRock, Inc.↑ INC | +539,834 | $327.97M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
Commodore Capital LP↓ DEC | -975,000 | $47.97M |
Capital International Investors↓ DEC | -740,232 | $155.54M |
BRAIDWELL LP↓ DEC | -486,624 | $77.83M |
MILLENNIUM MANAGEMENT LLC↓ DEC | -433,271 | $11.73M |
BARCLAYS PLC↓ DEC | -362,755 | $13.85M |
STEMPOINT CAPITAL LP↓ DEC | -207,850 | $8.18M |
ALLIANCEBERNSTEIN L.P.↓ DEC | -190,517 | $62.90M |
TimesSquare Capital Management, LLC↓ DEC | -173,447 | $20.89M |
Aberdeen Group plc↓ DEC | -140,362 | $35.47M |
Rhenman & Partners Asset Management AB↓ DEC | -111,000 | $1.63M |