第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
FMR LLCCIK 0000315066 | 2,816,494 | $87.06M | +9,052 | ↑ INC |
TCG Crossover Management, LLCCIK 0001839948 | 1,204,891 | $37.24M | +1,204,891 | NEW |
Aberdeen Group plcCIK 0001716774 | 1,141,824 | $35.29M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 860,352 | $26.59M | +5,989 | ↑ INC |
BRAIDWELL LPCIK 0001920938 | 847,151 | $26.19M | -80,373 | ↓ DEC |
First Light Asset Management, LLCCIK 0001600004 | 647,743 | $20.02M | +445,350 | ↑ INC |
BAKER BROS. ADVISORS LPCIK 0001263508 | 607,788 | $18.79M | -295,612 | ↓ DEC |
5AM Venture Management, LLCCIK 0001799883 | 606,660 | $18.75M | – | no_change |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 473,532 | $14.64M | +473,532 | NEW |
Vestal Point Capital, LPCIK 0001974915 | 328,000 | $10.14M | – | no_change |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 293,475 | $9.07M | +54,562 | ↑ INC |
KENNEDY CAPITAL MANAGEMENT LLCCIK 0000884589 | 286,682 | $8.86M | +77,457 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 268,273 | $8.29M | +4,713 | ↑ INC |
MARSHALL WACE, LLPCIK 0001318757 | 229,595 | $7.10M | +198,677 | ↑ INC |
ORBIMED ADVISORS LLCCIK 0001055951 | 226,600 | $7.00M | -348,000 | ↓ DEC |
STATE STREET CORPCIK 0000093751 | 213,505 | $6.60M | +4,380 | ↑ INC |
Squarepoint Ops LLCCIK 0001642575 | 164,419 | $5.08M | -35,227 | ↓ DEC |
Ikarian Capital, LLCCIK 0001778253 | 157,537 | $4.87M | -6,159 | ↓ DEC |
AMERIPRISE FINANCIAL INCCIK 0000820027 | 143,432 | $4.43M | +135,916 | ↑ INC |
Opaleye Management Inc.CIK 0001595855 | 123,000 | $3.80M | -91,747 | ↓ DEC |
Soleus Capital Management, L.P.CIK 0001802630 | 121,684 | $3.76M | +96,684 | ↑ INC |
WELLS FARGO & COMPANY/MNCIK 0000072971 | 112,664 | $3.48M | -7,747 | ↓ DEC |
Woodline Partners LPCIK 0001784547 | 100,000 | $3.09M | -100,000 | ↓ DEC |
ExodusPoint Capital Management, LPCIK 0001736225 | 83,679 | $2.59M | -27,509 | ↓ DEC |
Prosight Management, LPCIK 0001617201 | 79,872 | $2.47M | -155,128 | ↓ DEC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
TCG Crossover Management, LLCNEW | +1,204,891 | $37.24M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +473,532 | $14.64M |
First Light Asset Management, LLC↑ INC | +445,350 | $20.02M |
MARSHALL WACE, LLP↑ INC | +198,677 | $7.10M |
PRICE T ROWE ASSOCIATES INC /MD/↑ INC | +145,733 | $5.07K |
AMERIPRISE FINANCIAL INC↑ INC | +135,916 | $4.43M |
Soleus Capital Management, L.P.↑ INC | +96,684 | $3.76M |
KENNEDY CAPITAL MANAGEMENT LLC↑ INC | +77,457 | $8.86M |
VANGUARD FIDUCIARY TRUST CONEW | +67,895 | $2.10M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +63,607 | $1.97M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
Point72 Asset Management, L.P.↓ DEC | -423,734 | $2.12M |
ORBIMED ADVISORS LLC↓ DEC | -348,000 | $7.00M |
CITADEL ADVISORS LLC↓ DEC | -332,817 | $1.62M |
BAKER BROS. ADVISORS LP↓ DEC | -295,612 | $18.79M |
MILLENNIUM MANAGEMENT LLC↓ DEC | -242,472 | $1.80M |
Tetragon Partners GP Ltd↓ DEC | -206,140 | $1.16M |
Prosight Management, LP↓ DEC | -155,128 | $2.47M |
Invesco Ltd.↓ DEC | -120,503 | $237.23K |
Woodline Partners LP↓ DEC | -100,000 | $3.09M |
Opaleye Management Inc.↓ DEC | -91,747 | $3.80M |