第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
TPG GP A, LLCCIK 0001903793 | 6,494,962 | $260.38M | -250,000 | ↓ DEC |
ORBIMED ADVISORS LLCCIK 0001055951 | 3,530,702 | $141.55M | -30,953 | ↓ DEC |
VIKING GLOBAL INVESTORS LPCIK 0001103804 | 3,195,181 | $128.09M | – | no_change |
Atlas Venture Life Science Advisors, LLCCIK 0001917529 | 2,995,602 | $120.09M | – | no_change |
Enavate Sciences GP, LLCCIK 0001953107 | 2,478,030 | $99.34M | – | no_change |
JENNISON ASSOCIATES LLCCIK 0000053417 | 1,451,220 | $58.18M | +335,942 | ↑ INC |
JPMORGAN CHASE & COCIK 0000019617 | 1,465,014 | $53.71M | +233,195 | ↑ INC |
BlackRock, Inc.CIK 0002012383 | 1,295,867 | $51.95M | +4,268 | ↑ INC |
CITADEL ADVISORS LLCCIK 0001423053 | 1,166,931 | $46.78M | +79,606 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 1,029,497 | $41.27M | +1,029,497 | NEW |
DEERFIELD MANAGEMENT COMPANY, L.P.CIK 0001009258 | 970,590 | $38.91M | – | no_change |
STATE STREET CORPCIK 0000093751 | 756,227 | $30.32M | +62,832 | ↑ INC |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 658,439 | $26.40M | -520,659 | ↓ DEC |
EVENTIDE ASSET MANAGEMENT, LLCCIK 0001442891 | 645,530 | $25.88M | +6,485 | ↑ INC |
Aberdeen Group plcCIK 0001716774 | 564,175 | $22.62M | -275,785 | ↓ DEC |
BAKER BROS. ADVISORS LPCIK 0001263508 | 400,000 | $16.04M | – | no_change |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 389,872 | $15.63M | +9,830 | ↑ INC |
Siren, L.L.C.CIK 0002005245 | 300,000 | $12.03M | – | no_change |
Sio Capital Management, LLCCIK 0001482416 | 294,340 | $11.80M | +294,340 | NEW |
Soleus Capital Management, L.P.CIK 0001802630 | 293,500 | $11.77M | +25,000 | ↑ INC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 263,174 | $10.55M | +226,905 | ↑ INC |
Ensign Peak Advisors, IncCIK 0001454984 | 255,636 | $10.25M | +175,774 | ↑ INC |
Candriam S.C.A.CIK 0001537014 | 236,813 | $9.49M | +236,813 | NEW |
Kalehua Capital Management LLCCIK 0002106181 | 197,072 | $7.90M | – | no_change |
FRANKLIN RESOURCES INCCIK 0000038777 | 175,483 | $7.04M | – | no_change |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +1,029,497 | $41.27M |
JENNISON ASSOCIATES LLC↑ INC | +335,942 | $58.18M |
Sio Capital Management, LLCNEW | +294,340 | $11.80M |
Candriam S.C.A.NEW | +236,813 | $9.49M |
JPMORGAN CHASE & CO↑ INC | +233,195 | $53.71M |
GOLDMAN SACHS GROUP INC↑ INC | +226,905 | $10.55M |
Ensign Peak Advisors, Inc↑ INC | +175,774 | $10.25M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +142,081 | $5.70M |
Point72 Asset Management, L.P.NEW | +136,549 | $5.47M |
GordonMD Global Investments LPNEW | +136,000 | $5.45M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
PERCEPTIVE ADVISORS LLC↓ DEC | -520,659 | $26.40M |
Aberdeen Group plc↓ DEC | -275,785 | $22.62M |
TPG GP A, LLC↓ DEC | -250,000 | $260.38M |
Invesco Ltd.↓ DEC | -100,375 | $432.45K |
PRICE T ROWE ASSOCIATES INC /MD/↓ DEC | -74,997 | $30.32K |
Longaeva Partners L.P.↓ DEC | -67,036 | $508.86K |
SUPERSTRING CAPITAL MANAGEMENT LP↓ DEC | -39,569 | $5.65M |
ORBIMED ADVISORS LLC↓ DEC | -30,953 | $141.55M |
TD ASSET MANAGEMENT INC↓ DEC | -30,356 | $3.33M |
BARCLAYS PLC↓ DEC | -29,787 | $737.06K |