第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
FMR LLCCIK 0000315066 | 4,303,188 | $309.61M | +4,202,059 | ↑ INC |
BVF INC/ILCIK 0001056807 | 2,559,595 | $184.16M | +1,000,000 | ↑ INC |
Two Seas Capital LPCIK 0001823138 | 1,959,178 | $140.96M | +1,213,993 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 1,197,055 | $86.13M | +1,197,055 | NEW |
TWO SIGMA INVESTMENTS, LPCIK 0001179392 | 930,741 | $66.97M | +457,727 | ↑ INC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 903,190 | $64.98M | -255,120 | ↓ DEC |
Prosight Management, LPCIK 0001617201 | 735,000 | $52.88M | +180,367 | ↑ INC |
BlackRock, Inc.CIK 0002012383 | 692,650 | $49.84M | +47,043 | ↑ INC |
CITADEL ADVISORS LLCCIK 0001423053 | 665,431 | $47.88M | +176,054 | ↑ INC |
MORGAN STANLEYCIK 0000895421 | 659,387 | $47.44M | +92,966 | ↑ INC |
ARMISTICE CAPITAL, LLCCIK 0001601086 | 578,000 | $41.59M | -18,000 | ↓ DEC |
Invesco Ltd.CIK 0000914208 | 567,458 | $40.83M | +99,299 | ↑ INC |
Sofinnova Investments, Inc.CIK 0001631134 | 509,546 | $36.66M | +70,916 | ↑ INC |
Woodline Partners LPCIK 0001784547 | 415,335 | $29.88M | +311,335 | ↑ INC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 404,277 | $29.09M | -49,798 | ↓ DEC |
Bronte Capital Management Pty Ltd.CIK 0001471085 | 400,756 | $28.83M | +400,756 | NEW |
EMERALD ADVISERS, LLCCIK 0001015083 | 394,604 | $28.39M | +10,262 | ↑ INC |
Qube Research & Technologies LtdCIK 0001729829 | 390,675 | $28.11M | +66,760 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 346,795 | $24.96M | +92,434 | ↑ INC |
UBS Group AGCIK 0001610520 | 320,172 | $23.04M | +32,611 | ↑ INC |
GREAT POINT PARTNERS LLCCIK 0001281446 | 316,453 | $22.77M | +105,721 | ↑ INC |
Vestal Point Capital, LPCIK 0001974915 | 285,000 | $20.51M | +285,000 | NEW |
22NW, LPCIK 0001694297 | 281,115 | $20.23M | -50,000 | ↓ DEC |
PRIMECAP MANAGEMENT CO/CA/CIK 0000763212 | 279,150 | $20.08M | -1,000 | ↓ DEC |
ORBIMED ADVISORS LLCCIK 0001055951 | 275,000 | $19.79M | +275,000 | NEW |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
FMR LLC↑ INC | +4,202,059 | $309.61M |
Two Seas Capital LP↑ INC | +1,213,993 | $140.96M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +1,197,055 | $86.13M |
BVF INC/IL↑ INC | +1,000,000 | $184.16M |
TWO SIGMA INVESTMENTS, LP↑ INC | +457,727 | $66.97M |
LORD, ABBETT & CO. LLCNEW | +405,080 | $29.15K |
Bronte Capital Management Pty Ltd.NEW | +400,756 | $28.83M |
Woodline Partners LP↑ INC | +311,335 | $29.88M |
Vestal Point Capital, LPNEW | +285,000 | $20.51M |
ORBIMED ADVISORS LLCNEW | +275,000 | $19.79M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
FARALLON CAPITAL MANAGEMENT, L.L.C.↓ DEC | -787,000 | $287.80K |
Point72 Asset Management, L.P.↓ DEC | -438,055 | $961.54K |
SUSQUEHANNA INTERNATIONAL GROUP, LLP↓ DEC | -255,120 | $64.98M |
BALYASNY ASSET MANAGEMENT L.P.↓ DEC | -246,170 | $2.58M |
RENAISSANCE TECHNOLOGIES LLC↓ DEC | -131,100 | $3.01M |
GROUP ONE TRADING LLC↓ DEC | -107,600 | $2.20M |
HRT FINANCIAL LP↓ DEC | -102,776 | $5.08K |
BNP PARIBAS FINANCIAL MARKETS↓ DEC | -88,759 | $8.74M |
ACADIAN ASSET MANAGEMENT LLC↓ DEC | -70,252 | $141.00 |
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.↓ DEC | -65,786 | $8.80M |