第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
FMR LLCCIK 0000315066 | 7,767,686 | $651.86M | +1,336,357 | ↑ INC |
BlackRock, Inc.CIK 0002012383 | 3,175,703 | $266.50M | +1,260,467 | ↑ INC |
WELLINGTON MANAGEMENT GROUP LLPCIK 0000902219 | 2,595,783 | $217.84M | +92,593 | ↑ INC |
Fairmount Funds Management LLCCIK 0001802528 | 2,537,191 | $212.92M | +400,000 | ↑ INC |
Avidity Partners Management LPCIK 0001791827 | 2,104,184 | $184.75M | – | no_change |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 2,031,249 | $170.46M | +2,031,249 | NEW |
Octagon Capital Advisors LPCIK 0001839435 | 1,946,667 | $163.36M | -470,000 | ↓ DEC |
TCG Crossover Management, LLCCIK 0001839948 | 1,676,624 | $140.70M | – | no_change |
CITADEL ADVISORS LLCCIK 0001423053 | 1,648,983 | $138.38M | +569,249 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 1,398,913 | $117.40M | -108,706 | ↓ DEC |
Venrock Adviser, LLCCIK 0001615982 | 1,180,000 | $99.03M | +180,000 | ↑ INC |
FRED ALGER MANAGEMENT, LLCCIK 0000003520 | 1,161,923 | $97.51M | +1,128,463 | ↑ INC |
DEERFIELD MANAGEMENT COMPANY, L.P.CIK 0001009258 | 1,019,813 | $85.58M | +1,019,813 | NEW |
FRANKLIN RESOURCES INCCIK 0000038777 | 968,182 | $81.25M | +505,356 | ↑ INC |
Cormorant Asset Management, LPCIK 0001583977 | 950,000 | $79.72M | +950,000 | NEW |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 916,211 | $76.90M | +239,553 | ↑ INC |
BRAIDWELL LPCIK 0001920938 | 899,364 | $75.47M | -374,571 | ↓ DEC |
BAKER BROS. ADVISORS LPCIK 0001263508 | 852,164 | $71.51M | +62,405 | ↑ INC |
FARALLON CAPITAL MANAGEMENT, L.L.C.CIK 0000909661 | 836,000 | $70.16M | +836,000 | NEW |
UBS Group AGCIK 0001610520 | 781,282 | $65.57M | +174,662 | ↑ INC |
SILVERARC CAPITAL MANAGEMENT, LLCCIK 0001816307 | 654,746 | $54.95M | -95,390 | ↓ DEC |
Point72 Asset Management, L.P.CIK 0001603466 | 643,599 | $54.01M | -522,489 | ↓ DEC |
Catalio Capital Management, LPCIK 0001958125 | 560,308 | $47.02M | -93,264 | ↓ DEC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 548,010 | $45.99M | -29,009 | ↓ DEC |
JENNISON ASSOCIATES LLCCIK 0000053417 | 485,136 | $40.71M | +485,136 | NEW |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +2,031,249 | $170.46M |
FMR LLC↑ INC | +1,336,357 | $651.86M |
T. Rowe Price Investment Management, Inc.NEW | +1,292,182 | $108.44K |
BlackRock, Inc.↑ INC | +1,260,467 | $266.50M |
FRED ALGER MANAGEMENT, LLC↑ INC | +1,128,463 | $97.51M |
DEERFIELD MANAGEMENT COMPANY, L.P.NEW | +1,019,813 | $85.58M |
Cormorant Asset Management, LPNEW | +950,000 | $79.72M |
FARALLON CAPITAL MANAGEMENT, L.L.C.NEW | +836,000 | $70.16M |
CITADEL ADVISORS LLC↑ INC | +569,249 | $138.38M |
PRICE T ROWE ASSOCIATES INC /MD/↑ INC | +530,915 | $96.25K |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
MARSHALL WACE, LLP↓ DEC | -666,604 | $28.69M |
Point72 Asset Management, L.P.↓ DEC | -522,489 | $54.01M |
Tri Locum Partners LP↓ DEC | -476,860 | $12.21M |
Octagon Capital Advisors LP↓ DEC | -470,000 | $163.36M |
RTW INVESTMENTS, LP↓ DEC | -418,604 | $20.82M |
MILLENNIUM MANAGEMENT LLC↓ DEC | -405,254 | $21.98M |
Bain Capital Life Sciences Investors, LLC↓ DEC | -381,122 | $30.42M |
BRAIDWELL LP↓ DEC | -374,571 | $75.47M |
BANK OF AMERICA CORP /DE/↓ DEC | -276,759 | $15.84M |
BNP PARIBAS FINANCIAL MARKETS↓ DEC | -240,001 | $19.78M |