第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
BlackRock, Inc.CIK 0002012383 | 7,170,868 | $157.97M | +2,604,366 | ↑ INC |
Deep Track Capital, LPCIK 0001856083 | 6,772,595 | $149.20M | +6,772,595 | NEW |
Samsara BioCapital, LLCCIK 0001744967 | 6,345,219 | $139.79M | +588,235 | ↑ INC |
Foresite Capital Management V, LLCCIK 0001792206 | 5,896,995 | $129.91M | +117,647 | ↑ INC |
venBio Partners LLCCIK 0001776382 | 4,528,408 | $99.76M | -91,395 | ↓ DEC |
Foresite Capital Management VI LLCCIK 0002013341 | 4,247,670 | $93.58M | – | no_change |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 4,032,266 | $88.83M | +4,032,266 | NEW |
Cormorant Asset Management, LPCIK 0001583977 | 3,949,241 | $87.00M | +313,645 | ↑ INC |
Nextech Invest, Ltd.CIK 0001595430 | 3,540,998 | $78.01M | +625,000 | ↑ INC |
Saturn V Capital Management LPCIK 0001964437 | 3,202,075 | $70.54M | +66,122 | ↑ INC |
UBS Group AGCIK 0001610520 | 3,054,865 | $67.30M | +2,940,868 | ↑ INC |
Octagon Capital Advisors LPCIK 0001839435 | 2,830,700 | $62.36M | +300,000 | ↑ INC |
MPM BioImpact LLCCIK 0001687078 | 2,386,529 | $52.58M | -15,463 | ↓ DEC |
BAKER BROS. ADVISORS LPCIK 0001263508 | 2,012,500 | $44.34M | +450,000 | ↑ INC |
SR ONE CAPITAL MANAGEMENT, LPCIK 0001910264 | 1,959,896 | $43.18M | – | no_change |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 1,918,415 | $42.27M | +430,789 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 1,801,812 | $39.69M | +542,366 | ↑ INC |
Invesco Ltd.CIK 0000914208 | 1,511,537 | $33.30M | +1,089,718 | ↑ INC |
Ikarian Capital, LLCCIK 0001778253 | 1,478,148 | $32.56M | +1,267,048 | ↑ INC |
MARSHALL WACE, LLPCIK 0001318757 | 1,172,749 | $25.84M | +799,848 | ↑ INC |
Weiss Asset Management LPCIK 0001357550 | 1,097,417 | $24.18M | +1,087,417 | ↑ INC |
PRINCIPAL FINANCIAL GROUP INCCIK 0001126328 | 1,058,051 | $23.31M | +1,058,051 | NEW |
FMR LLCCIK 0000315066 | 973,782 | $21.45M | +949,795 | ↑ INC |
GREAT POINT PARTNERS LLCCIK 0001281446 | 856,061 | $18.86M | +856,061 | NEW |
JPMORGAN CHASE & COCIK 0000019617 | 861,575 | $17.41M | +505,238 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
Deep Track Capital, LPNEW | +6,772,595 | $149.20M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +4,032,266 | $88.83M |
PRICE T ROWE ASSOCIATES INC /MD/↑ INC | +3,236,331 | $72.41K |
UBS Group AG↑ INC | +2,940,868 | $67.30M |
BlackRock, Inc.↑ INC | +2,604,366 | $157.97M |
Ikarian Capital, LLC↑ INC | +1,267,048 | $32.56M |
Invesco Ltd.↑ INC | +1,089,718 | $33.30M |
Weiss Asset Management LP↑ INC | +1,087,417 | $24.18M |
PRINCIPAL FINANCIAL GROUP INCNEW | +1,058,051 | $23.31M |
FMR LLC↑ INC | +949,795 | $21.45M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
Trium Capital LLP↓ DEC | -701,716 | $4.22M |
ORBIMED ADVISORS LLC↓ DEC | -554,567 | $12.08M |
MILLENNIUM MANAGEMENT LLC↓ DEC | -544,834 | $13.36M |
Omega Fund Management, LLC↓ DEC | -411,968 | $5.31M |
MORGAN STANLEY↓ DEC | -281,457 | $4.96M |
Ally Bridge Group (NY) LLC↓ DEC | -278,300 | $3.68M |
TOWERVIEW LLC↓ DEC | -272,706 | $4.90M |
JANE STREET GROUP, LLC↓ DEC | -141,633 | $2.40M |
venBio Partners LLC↓ DEC | -91,395 | $99.76M |
Mariner, LLC↓ DEC | -71,922 | $1.61M |