第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
BAKER BROS. ADVISORS LPCIK 0001263508 | 10,012,267 | $354.03M | – | no_change |
AMERICAN CENTURY COMPANIES INCCIK 0000748054 | 6,072,103 | $214.71M | +115,279 | ↑ INC |
FIRST TRUST ADVISORS LPCIK 0001125816 | 2,968,785 | $104.98M | +1,514,783 | ↑ INC |
PRIMECAP MANAGEMENT CO/CA/CIK 0000763212 | 2,539,990 | $89.81M | -24,310 | ↓ DEC |
CITADEL ADVISORS LLCCIK 0001423053 | 2,331,284 | $82.43M | +1,028,816 | ↑ INC |
Holocene Advisors, LPCIK 0001700574 | 2,317,326 | $81.94M | -151,704 | ↓ DEC |
BVF INC/ILCIK 0001056807 | 2,000,000 | $70.72M | +2,000,000 | NEW |
RTW INVESTMENTS, LPCIK 0001493215 | 1,672,356 | $59.13M | – | no_change |
Avoro Capital Advisors LLCCIK 0001633313 | 1,200,000 | $42.43M | -200,000 | ↓ DEC |
PANAGORA ASSET MANAGEMENT INCCIK 0000883677 | 932,942 | $32.99M | +3,978 | ↑ INC |
Man Group plcCIK 0001637460 | 625,046 | $22.10M | +312,534 | ↑ INC |
Woodline Partners LPCIK 0001784547 | 558,567 | $19.75M | – | no_change |
RICE HALL JAMES & ASSOCIATES, LLCCIK 0001230765 | 390,344 | $13.80M | +10,886 | ↑ INC |
AQR CAPITAL MANAGEMENT LLCCIK 0001167557 | 383,977 | $13.58M | -130,347 | ↓ DEC |
Eagle Health Investments LPCIK 0001842545 | 238,673 | $8.44M | +156,873 | ↑ INC |
Engineers Gate Manager LPCIK 0001620220 | 208,497 | $7.37M | +160,766 | ↑ INC |
Rock Springs Capital Management LPCIK 0001595725 | 183,986 | $6.51M | +44,758 | ↑ INC |
FRANKLIN RESOURCES INCCIK 0000038777 | 182,535 | $6.45M | -10,272 | ↓ DEC |
Hudson Bay Capital Management LPCIK 0001393825 | 173,626 | $6.14M | +148,626 | ↑ INC |
Rafferty Asset Management, LLCCIK 0001389426 | 162,424 | $5.74M | -40,840 | ↓ DEC |
Tetragon Partners GP LtdCIK 0001515070 | 159,791 | $5.65M | +18,619 | ↑ INC |
DEUTSCHE BANK AG\CIK 0000948046 | 149,734 | $5.29M | +15,273 | ↑ INC |
Rhenman & Partners Asset Management ABCIK 0001599882 | 133,250 | $4.71M | – | no_change |
Knott David M JrCIK 0001892770 | 120,000 | $4.24M | +25,000 | ↑ INC |
Vident Advisory, LLCCIK 0001744347 | 84,090 | $2.97M | +1,796 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
BVF INC/ILNEW | +2,000,000 | $70.72M |
FIRST TRUST ADVISORS LP↑ INC | +1,514,783 | $104.98M |
CITADEL ADVISORS LLC↑ INC | +1,028,816 | $82.43M |
T. Rowe Price Investment Management, Inc.↑ INC | +892,177 | $31.62K |
Man Group plc↑ INC | +312,534 | $22.10M |
Engineers Gate Manager LP↑ INC | +160,766 | $7.37M |
Eagle Health Investments LP↑ INC | +156,873 | $8.44M |
Hudson Bay Capital Management LP↑ INC | +148,626 | $6.14M |
AMERICAN CENTURY COMPANIES INC↑ INC | +115,279 | $214.71M |
Rock Springs Capital Management LP↑ INC | +44,758 | $6.51M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
PRICE T ROWE ASSOCIATES INC /MD/↓ DEC | -4,334,387 | $164.94K |
GREAT POINT PARTNERS LLC↓ DEC | -825,044 | $1.77M |
Point72 Asset Management, L.P.↓ DEC | -463,719 | $1.17M |
CANADA PENSION PLAN INVESTMENT BOARD↓ DEC | -262,100 | $1.71M |
Bridgewater Associates, LP↓ DEC | -260,646 | $2.96M |
Edgestream Partners, L.P.↓ DEC | -238,473 | $1.87M |
Avoro Capital Advisors LLC↓ DEC | -200,000 | $42.43M |
Holocene Advisors, LP↓ DEC | -151,704 | $81.94M |
AQR CAPITAL MANAGEMENT LLC↓ DEC | -130,347 | $13.58M |
INTECH INVESTMENT MANAGEMENT LLC↓ DEC | -98,614 | $2.16M |