第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
BAKER BROS. ADVISORS LPCIK 0001263508 | 42,896,690 | $954.88M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 21,550,921 | $479.72M | +795,469 | ↑ INC |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 8,671,645 | $193.03M | +8,671,645 | NEW |
STATE STREET CORPCIK 0000093751 | 8,332,771 | $185.49M | +422,038 | ↑ INC |
RTW INVESTMENTS, LPCIK 0001493215 | 7,144,524 | $159.04M | – | no_change |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 5,661,400 | $126.02M | +5,661,400 | NEW |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 3,464,689 | $77.14M | +225,238 | ↑ INC |
FIRST TRUST ADVISORS LPCIK 0001125816 | 3,343,868 | $74.43M | +1,073,834 | ↑ INC |
DIMENSIONAL FUND ADVISORS LPCIK 0000354204 | 3,155,160 | $70.22M | +234,186 | ↑ INC |
Palo Alto Investors LPCIK 0001306923 | 2,872,695 | $63.95M | +388,664 | ↑ INC |
Point72 Asset Management, L.P.CIK 0001603466 | 2,605,316 | $57.99M | -771,995 | ↓ DEC |
BRAIDWELL LPCIK 0001920938 | 2,471,199 | $55.01M | +439,178 | ↑ INC |
Pictet Asset Management Holding SACIK 0001993888 | 2,026,044 | $44.74M | +478,941 | ↑ INC |
RENAISSANCE TECHNOLOGIES LLCCIK 0001037389 | 1,724,196 | $38.38M | +191,600 | ↑ INC |
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPCIK 0001164508 | 1,569,491 | $34.94M | +66,874 | ↑ INC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 1,557,804 | $34.68M | -12,247 | ↓ DEC |
BANK OF AMERICA CORP /DE/CIK 0000070858 | 1,553,770 | $34.59M | +332,325 | ↑ INC |
Frazier Life Sciences Management, L.P.CIK 0001892134 | 1,438,198 | $32.01M | +141,000 | ↑ INC |
Artisan Partners Limited PartnershipCIK 0001466153 | 1,331,813 | $29.65M | +1,015,520 | ↑ INC |
FRED ALGER MANAGEMENT, LLCCIK 0000003520 | 1,277,151 | $28.43M | -282,811 | ↓ DEC |
NORTHERN TRUST CORPCIK 0000073124 | 1,272,611 | $28.33M | +36,782 | ↑ INC |
CHARLES SCHWAB INVESTMENT MANAGEMENT INCCIK 0000884546 | 1,173,560 | $26.12M | +1,243 | ↑ INC |
MORGAN STANLEYCIK 0000895421 | 1,093,151 | $24.33M | -48,823 | ↓ DEC |
Nuveen, LLCCIK 0001871926 | 1,036,987 | $23.08M | -20,540 | ↓ DEC |
Rockefeller Capital Management L.P.CIK 0001739439 | 1,027,357 | $22.87M | -85,683 | ↓ DEC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +8,671,645 | $193.03M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +5,661,400 | $126.02M |
FIRST TRUST ADVISORS LP↑ INC | +1,073,834 | $74.43M |
Artisan Partners Limited Partnership↑ INC | +1,015,520 | $29.65M |
VANGUARD FIDUCIARY TRUST CONEW | +875,720 | $19.49M |
JANE STREET GROUP, LLC↑ INC | +847,765 | $19.62M |
BlackRock, Inc.↑ INC | +795,469 | $479.72M |
Woodline Partners LP↑ INC | +524,948 | $15.06M |
Pictet Asset Management Holding SA↑ INC | +478,941 | $44.74M |
BRAIDWELL LP↑ INC | +439,178 | $55.01M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
EMERALD ADVISERS, LLC↓ DEC | -782,560 | $637.46K |
Point72 Asset Management, L.P.↓ DEC | -771,995 | $57.99M |
CITADEL ADVISORS LLC↓ DEC | -746,799 | $14.66M |
ALGERT GLOBAL LLC↓ DEC | -473,948 | $3.13K |
EMERALD MUTUAL FUND ADVISERS TRUST↓ DEC | -467,930 | $368.98K |
MARSHALL WACE, LLP↓ DEC | -417,192 | $1.70M |
FMR LLC↓ DEC | -376,623 | $7.80M |
TWO SIGMA INVESTMENTS, LP↓ DEC | -343,996 | $17.25M |
BARCLAYS PLC↓ DEC | -340,501 | $618.89K |
UBS Group AG↓ DEC | -320,843 | $9.98M |