| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 7, 2026 | Fordyce Marshall | PRESIDENT AND CEO | S | 2,200 | $43.5947 | $95.91K |
| Jul 7, 2026 | Fordyce Marshall | PRESIDENT AND CEO | S | 10,500 | $42.8578 | $450.01K |
| Jul 7, 2026 | Fordyce Marshall | PRESIDENT AND CEO | S | 32,550 | $42.0736 | $1.37M |
| Jul 7, 2026 | Fordyce Marshall | PRESIDENT AND CEO | S | 1,000 | $40.7762 | $40.78K |
| Jun 23, 2026 | Fordyce Marshall | PRESIDENT AND CEO | S | 88 | $38.4300 | $3.38K |
| Jun 23, 2026 | Fordyce Marshall | PRESIDENT AND CEO | S | 18,412 | $37.9311 | $698.39K |
| May 21, 2026 | ENRIGHT PATRICK G | Director | A | 17,084 | $0.0000 | $0.00 |
| May 21, 2026 | MORRISSEY MICHAEL | Director | A | 17,084 | $0.0000 | $0.00 |
| May 21, 2026 | Hall Kimball | Director | A | 17,084 | $0.0000 | $0.00 |
| May 21, 2026 | Meyers James R | Director | A | 17,084 | $0.0000 | $0.00 |
| May 21, 2026 | Oliger Christy J. | Director | A | 17,084 | $0.0000 | $0.00 |
| May 21, 2026 | SEIDENBERG BETH C | Director | A | 17,084 | $0.0000 | $0.00 |
| May 21, 2026 | Cheng Andrew | Director | A | 17,084 | $0.0000 | $0.00 |
| May 21, 2026 | Morrison Scott W | Director | A | 17,084 | $0.0000 | $0.00 |
| May 12, 2026 | Fordyce Marshall | PRESIDENT AND CEO | S | 4,281 | $37.0868 | $158.77K |
| May 12, 2026 | Fordyce Marshall | PRESIDENT AND CEO | S | 14,219 | $36.6396 | $520.98K |
| Apr 14, 2026 | Fordyce Marshall | PRESIDENT AND CEO | S | 900 | $45.5114 | $40.96K |
| Apr 14, 2026 | Fordyce Marshall | PRESIDENT AND CEO | S | 7,921 | $44.5784 | $353.11K |
| Apr 14, 2026 | Fordyce Marshall | PRESIDENT AND CEO | S | 14,130 | $43.6649 | $616.99K |
| Mar 23, 2026 | Wright-Mitchell Jane | Chief Legal Officer | A | 56,850 | $0.0000 | $0.00 |
| Mar 23, 2026 | Wright-Mitchell Jane | Chief Legal Officer | A | 42,403 | $0.0000 | $0.00 |
| Mar 13, 2026 | Young Joseph R | SVP, FINANCE, CHIEF ACCT OFFCR | M | 10,000 | $0.0000 | $0.00 |
| Mar 13, 2026 | Young Joseph R | SVP, FINANCE, CHIEF ACCT OFFCR | M | 10,000 | $3.9396 | $39.40K |
| Mar 5, 2026 | Hite Christopher | Director | A | 24,937 | $0.0000 | $0.00 |
| Feb 23, 2026 | Skelton Laurence Matthew | Chief Commercial Officer | S | 1,582 | $41.9839 | $66.42K |
| Feb 23, 2026 | Turner William D. | Chief Regulatory Officer | S | 2,187 | $41.9839 | $91.82K |
| Feb 23, 2026 | JOHNSON DAVID LEE | Chief Operating Officer | S | 2,579 | $41.9839 | $108.28K |
| Feb 23, 2026 | Fordyce Marshall | PRESIDENT AND CEO | S | 16,925 | $41.9839 | $710.58K |
| Feb 23, 2026 | Grant Sean | CHIEF FINANCIAL OFFICER | S | 4,949 | $41.9839 | $207.78K |
| Feb 23, 2026 | Young Joseph R | SVP, FINANCE, CHIEF ACCT OFFCR | S | 3,117 | $41.9839 | $130.86K |
| Feb 23, 2026 | Brenner Robert | Chief Medical Officer | S | 2,151 | $41.9839 | $90.31K |
| Feb 4, 2026 | Turner William D. | Chief Regulatory Officer | A | 50,000 | $0.0000 | $0.00 |
| Feb 4, 2026 | Turner William D. | Chief Regulatory Officer | A | 25,000 | $0.0000 | $0.00 |
| Feb 4, 2026 | JOHNSON DAVID LEE | Chief Operating Officer | A | 40,000 | $0.0000 | $0.00 |
| Feb 4, 2026 | JOHNSON DAVID LEE | Chief Operating Officer | A | 20,000 | $0.0000 | $0.00 |
| Feb 4, 2026 | Brenner Robert | Chief Medical Officer | A | 50,000 | $0.0000 | $0.00 |
| Feb 4, 2026 | Brenner Robert | Chief Medical Officer | A | 25,000 | $0.0000 | $0.00 |
| Feb 4, 2026 | Skelton Laurence Matthew | Chief Commercial Officer | A | 40,000 | $0.0000 | $0.00 |
| Feb 4, 2026 | Skelton Laurence Matthew | Chief Commercial Officer | A | 20,000 | $0.0000 | $0.00 |
| Feb 4, 2026 | Grant Sean | CHIEF FINANCIAL OFFICER | A | 50,000 | $0.0000 | $0.00 |
| Feb 4, 2026 | Grant Sean | CHIEF FINANCIAL OFFICER | A | 25,000 | $0.0000 | $0.00 |
| Feb 4, 2026 | Young Joseph R | SVP, FINANCE, CHIEF ACCT OFFCR | A | 20,000 | $0.0000 | $0.00 |
| Feb 4, 2026 | Young Joseph R | SVP, FINANCE, CHIEF ACCT OFFCR | A | 10,000 | $0.0000 | $0.00 |
| Feb 4, 2026 | Fordyce Marshall | PRESIDENT AND CEO | A | 137,500 | $0.0000 | $0.00 |
| Feb 4, 2026 | Fordyce Marshall | PRESIDENT AND CEO | A | 68,800 | $0.0000 | $0.00 |
| Dec 15, 2025 | Turner William D. | Chief Regulatory Officer | M | 10,000 | $0.0000 | $0.00 |
| Dec 15, 2025 | Turner William D. | Chief Regulatory Officer | S | 10,000 | $50.0767 | $500.77K |
| Dec 15, 2025 | Turner William D. | Chief Regulatory Officer | M | 10,000 | $15.5300 | $155.30K |
| Dec 11, 2025 | ENRIGHT PATRICK G | Director | P | 5,882 | $42.5000 | $249.99K |
| Dec 8, 2025 | Turner William D. | Chief Regulatory Officer | M | 10,000 | $0.0000 | $0.00 |