First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
Venrock Adviser, LLCCIK 0001615982 | 1,675,262 | $26.79M | +1,237,554 | ↑ INC |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 1,447,782 | $23.15M | +1,008,640 | ↑ INC |
Ikarian Capital, LLCCIK 0001778253 | 1,131,900 | $18.10M | +164,300 | ↑ INC |
Stonepine Capital Management, LLCCIK 0001440771 | 975,200 | $15.59M | +963,316 | ↑ INC |
MORGAN STANLEYCIK 0000895421 | 596,564 | $9.54M | +188 | ↑ INC |
Velan Capital Investment Management LPCIK 0001848809 | 583,333 | $9.33M | +500,000 | ↑ INC |
Point72 Asset Management, L.P.CIK 0001603466 | 533,965 | $8.54M | +110,550 | ↑ INC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 533,889 | $8.54M | +231,416 | ↑ INC |
ARMISTICE CAPITAL, LLCCIK 0001601086 | 478,827 | $7.66M | +478,827 | NEW |
Siren, L.L.C.CIK 0002005245 | 427,141 | $6.83M | – | no_change |
BOOTHBAY FUND MANAGEMENT, LLCCIK 0001549230 | 399,891 | $6.39M | +47,685 | ↑ INC |
TD ASSET MANAGEMENT INCCIK 0001056053 | 399,184 | $6.38M | +399,184 | NEW |
UBS Group AGCIK 0001610520 | 381,419 | $6.10M | +380,743 | ↑ INC |
RTW INVESTMENTS, LPCIK 0001493215 | 370,246 | $5.92M | -8,100 | ↓ DEC |
MARSHALL WACE, LLPCIK 0001318757 | 352,572 | $5.64M | +54,419 | ↑ INC |
BVF INC/ILCIK 0001056807 | 339,549 | $5.43M | – | no_change |
GREAT POINT PARTNERS LLCCIK 0001281446 | 327,307 | $5.23M | +327,307 | NEW |
Woodline Partners LPCIK 0001784547 | 323,911 | $5.18M | +180,430 | ↑ INC |
FMR LLCCIK 0000315066 | 322,600 | $5.16M | +181,500 | ↑ INC |
AMERIPRISE FINANCIAL INCCIK 0000820027 | 279,537 | $4.47M | +279,537 | NEW |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 263,421 | $4.21M | +263,421 | NEW |
Avidity Partners Management LPCIK 0001791827 | 265,934 | $3.49M | +265,934 | NEW |
ADAR1 Capital Management, LLCCIK 0001940272 | 213,462 | $3.41M | +149,789 | ↑ INC |
Vivo Capital, LLCCIK 0001674712 | 208,333 | $3.33M | – | no_change |
BOONE CAPITAL MANAGEMENT LLCCIK 0001882053 | 200,000 | $3.20M | +200,000 | NEW |
| Filer | Δ Shares | Value |
|---|---|---|
PRICE T ROWE ASSOCIATES INC /MD/↑ INC | +2,927,116 | $47.19K |
Venrock Adviser, LLC↑ INC | +1,237,554 | $26.79M |
PERCEPTIVE ADVISORS LLC↑ INC | +1,008,640 | $23.15M |
Stonepine Capital Management, LLC↑ INC | +963,316 | $15.59M |
Velan Capital Investment Management LP↑ INC | +500,000 | $9.33M |
ARMISTICE CAPITAL, LLCNEW | +478,827 | $7.66M |
TD ASSET MANAGEMENT INCNEW | +399,184 | $6.38M |
UBS Group AG↑ INC | +380,743 | $6.10M |
GREAT POINT PARTNERS LLCNEW | +327,307 | $5.23M |
AMERIPRISE FINANCIAL INCNEW | +279,537 | $4.47M |
| Filer | Δ Shares | Value |
|---|---|---|
DIADEMA PARTNERS LP↓ DEC | -63,432 | $2.87M |
SPHERA FUNDS MANAGEMENT LTD.↓ DEC | -54,096 | $2.17M |
RTW INVESTMENTS, LP↓ DEC | -8,100 | $5.92M |
Persistent Asset Partners Ltd↓ DEC | -7,090 | $930.33K |
Quadrature Capital Ltd↓ DEC | -5,176 | $247.40K |