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Institutional Holders · 13F

First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.

Ownership

Institutions74.8%
Insiders9.9%
Institutions Count113
Institutions 74.8%Insiders 9.9%Float (Other) 15.3%
13F Filers (top 25)25Quarter 2026-03-31
Top-25 Reported Value$375.21MSum of shown holders' market value
Net Position Change10 adds · 10 trimsLargest movers this quarter

Top Holders by Value

25 shown
FilerSharesMarket ValueΔ SharesChange
FMR LLCCIK 0000315066
2,816,494$87.06M+9,052↑ INC
TCG Crossover Management, LLCCIK 0001839948
1,204,891$37.24M+1,204,891NEW
Aberdeen Group plcCIK 0001716774
1,141,824$35.29M–no_change
BlackRock, Inc.CIK 0002012383
860,352$26.59M+5,989↑ INC
BRAIDWELL LPCIK 0001920938
847,151$26.19M-80,373↓ DEC
First Light Asset Management, LLCCIK 0001600004
647,743$20.02M+445,350↑ INC
BAKER BROS. ADVISORS LPCIK 0001263508
607,788$18.79M-295,612↓ DEC
5AM Venture Management, LLCCIK 0001799883
606,660$18.75M–no_change
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119
473,532$14.64M+473,532NEW
Vestal Point Capital, LPCIK 0001974915
328,000$10.14M–no_change
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194
293,475$9.07M+54,562↑ INC
KENNEDY CAPITAL MANAGEMENT LLCCIK 0000884589
286,682$8.86M+77,457↑ INC
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717
268,273$8.29M+4,713↑ INC
MARSHALL WACE, LLPCIK 0001318757
229,595$7.10M+198,677↑ INC
ORBIMED ADVISORS LLCCIK 0001055951
226,600$7.00M-348,000↓ DEC
STATE STREET CORPCIK 0000093751
213,505$6.60M+4,380↑ INC
Squarepoint Ops LLCCIK 0001642575
164,419$5.08M-35,227↓ DEC
Ikarian Capital, LLCCIK 0001778253
157,537$4.87M-6,159↓ DEC
AMERIPRISE FINANCIAL INCCIK 0000820027
143,432$4.43M+135,916↑ INC
Opaleye Management Inc.CIK 0001595855
123,000$3.80M-91,747↓ DEC
Soleus Capital Management, L.P.CIK 0001802630
121,684$3.76M+96,684↑ INC
WELLS FARGO & COMPANY/MNCIK 0000072971
112,664$3.48M-7,747↓ DEC
Woodline Partners LPCIK 0001784547
100,000$3.09M-100,000↓ DEC
ExodusPoint Capital Management, LPCIK 0001736225
83,679$2.59M-27,509↓ DEC
Prosight Management, LPCIK 0001617201
79,872$2.47M-155,128↓ DEC

Top Adds (Buyers)

FilerΔ SharesValue
TCG Crossover Management, LLCNEW
+1,204,891$37.24M
VANGUARD CAPITAL MANAGEMENT LLCNEW
+473,532$14.64M
First Light Asset Management, LLC↑ INC
+445,350$20.02M
MARSHALL WACE, LLP↑ INC
+198,677$7.10M
PRICE T ROWE ASSOCIATES INC /MD/↑ INC
+145,733$5.07K
AMERIPRISE FINANCIAL INC↑ INC
+135,916$4.43M
Soleus Capital Management, L.P.↑ INC
+96,684$3.76M
KENNEDY CAPITAL MANAGEMENT LLC↑ INC
+77,457$8.86M
VANGUARD FIDUCIARY TRUST CONEW
+67,895$2.10M
VANGUARD PORTFOLIO MANAGEMENT LLCNEW
+63,607$1.97M

Top Trims (Sellers)

FilerΔ SharesValue
Point72 Asset Management, L.P.↓ DEC
-423,734$2.12M
ORBIMED ADVISORS LLC↓ DEC
-348,000$7.00M
CITADEL ADVISORS LLC↓ DEC
-332,817$1.62M
BAKER BROS. ADVISORS LP↓ DEC
-295,612$18.79M
MILLENNIUM MANAGEMENT LLC↓ DEC
-242,472$1.80M
Tetragon Partners GP Ltd↓ DEC
-206,140$1.16M
Prosight Management, LP↓ DEC
-155,128$2.47M
Invesco Ltd.↓ DEC
-120,503$237.23K
Woodline Partners LP↓ DEC
-100,000$3.09M
Opaleye Management Inc.↓ DEC
-91,747$3.80M