First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
BVF INC/ILCIK 0001056807 | 1,251,788 | $31.18M | +1,251,788 | NEW |
Affinity Asset Advisors, LLCCIK 0001773195 | 1,069,519 | $26.64M | +321,137 | ↑ INC |
Samsara BioCapital, LLCCIK 0001744967 | 1,062,872 | $26.48M | +858,369 | ↑ INC |
ORBIMED ADVISORS LLCCIK 0001055951 | 801,144 | $19.96M | +801,144 | NEW |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 720,442 | $17.95M | +720,442 | NEW |
EVENTIDE ASSET MANAGEMENT, LLCCIK 0001442891 | 715,307 | $17.82M | +715,307 | NEW |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 715,307 | $17.82M | +715,307 | NEW |
Point72 Asset Management, L.P.CIK 0001603466 | 692,111 | $17.24M | +513,023 | ↑ INC |
ADAR1 Capital Management, LLCCIK 0001940272 | 524,441 | $13.06M | +457,364 | ↑ INC |
Velan Capital Investment Management LPCIK 0001848809 | 512,160 | $12.76M | +200,160 | ↑ INC |
BALYASNY ASSET MANAGEMENT L.P.CIK 0001218710 | 465,792 | $11.60M | +235,743 | ↑ INC |
Woodline Partners LPCIK 0001784547 | 457,441 | $11.39M | +457,441 | NEW |
UBS Group AGCIK 0001610520 | 392,871 | $9.79M | +385,001 | ↑ INC |
ACUTA CAPITAL PARTNERS, LLCCIK 0001582844 | 269,425 | $6.71M | +201,974 | ↑ INC |
BlackRock, Inc.CIK 0002012383 | 232,684 | $5.80M | +115,247 | ↑ INC |
KVP Capital Advisors, LPCIK 0001858198 | 226,575 | $5.64M | +226,575 | NEW |
MARSHALL WACE, LLPCIK 0001318757 | 222,634 | $5.55M | +137,019 | ↑ INC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 210,378 | $5.24M | -207,818 | ↓ DEC |
Opaleye Management Inc.CIK 0001595855 | 190,671 | $4.75M | – | no_change |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 171,386 | $4.27M | +87,407 | ↑ INC |
CITADEL ADVISORS LLCCIK 0001423053 | 142,337 | $3.55M | +110,252 | ↑ INC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 121,502 | $3.03M | +121,502 | NEW |
RENAISSANCE TECHNOLOGIES LLCCIK 0001037389 | 97,824 | $2.44M | -25,041 | ↓ DEC |
VANGUARD FIDUCIARY TRUST COCIK 0000933478 | 94,838 | $2.36M | +94,838 | NEW |
Eversept Partners, LPCIK 0001697013 | 73,161 | $1.82M | -120,410 | ↓ DEC |
| Filer | Δ Shares | Value |
|---|---|---|
BVF INC/ILNEW | +1,251,788 | $31.18M |
Samsara BioCapital, LLC↑ INC | +858,369 | $26.48M |
ORBIMED ADVISORS LLCNEW | +801,144 | $19.96M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +720,442 | $17.95M |
PERCEPTIVE ADVISORS LLCNEW | +715,307 | $17.82M |
EVENTIDE ASSET MANAGEMENT, LLCNEW | +715,307 | $17.82M |
Point72 Asset Management, L.P.↑ INC | +513,023 | $17.24M |
Woodline Partners LPNEW | +457,441 | $11.39M |
ADAR1 Capital Management, LLC↑ INC | +457,364 | $13.06M |
UBS Group AG↑ INC | +385,001 | $9.79M |
| Filer | Δ Shares | Value |
|---|---|---|
MILLENNIUM MANAGEMENT LLC↓ DEC | -207,818 | $5.24M |
Eversept Partners, LP↓ DEC | -120,410 | $1.82M |
GSA CAPITAL PARTNERS LLP↓ DEC | -63,245 | $643.00 |
RENAISSANCE TECHNOLOGIES LLC↓ DEC | -25,041 | $2.44M |
AQR CAPITAL MANAGEMENT LLC↓ DEC | -9,429 | $214.35K |
MORGAN STANLEY↓ DEC | -5,393 | $262.28K |
OMERS ADMINISTRATION Corp↓ DEC | -2,323 | $216.72K |
ACADIAN ASSET MANAGEMENT LLC↓ DEC | -2,140 | $8.36K |
CWM, LLC↓ DEC | -516 | $24.49K |
OSAIC HOLDINGS, INC.↓ DEC | -58 | $31.88K |