| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 4, 2026 | Chambers Michael Andrew | Director | A | 16,875 | – | – |
| Jun 4, 2026 | Barry Richard | Director | A | 16,875 | – | – |
| Jun 4, 2026 | Nicaise Claude | Director | A | 16,875 | – | – |
| Jun 4, 2026 | Connelly Deirdre P | Director | A | 16,875 | – | – |
| Jun 4, 2026 | Mayo Stephen | Director | A | 16,875 | – | – |
| Jun 4, 2026 | Wigzell Hans Lennart Rudolf | Director | A | 16,875 | – | – |
| Jun 4, 2026 | BEHRENS M KATHLEEN | Director | A | 16,875 | – | – |
| Jun 4, 2026 | Boor Kathryn Jean | Director | A | 16,875 | – | – |
| Mar 12, 2026 | Mayo Stephen | Director | S | 7,239 | $17.0200 | $123.21K |
| Mar 11, 2026 | Rothfuss Cristin | EVP, General Counsel | F | 974 | $17.0300 | $16.59K |
| Mar 11, 2026 | Rodino-Klapac Louise | President, R&D and Tech Ops | F | 948 | $17.0300 | $16.14K |
| Mar 11, 2026 | Wong Ryan Ho-Yan | Chief Financial Officer | F | 256 | $17.0300 | $4.36K |
| Mar 11, 2026 | Estepan Ian Michael | Chief Operating Officer | F | 1,097 | $17.0300 | $18.68K |
| Mar 9, 2026 | Estepan Ian Michael | Chief Operating Officer | F | 583 | $16.9500 | $9.88K |
| Mar 9, 2026 | Estepan Ian Michael | Chief Operating Officer | F | 1,036 | $16.9500 | $17.56K |
| Mar 9, 2026 | Rodino-Klapac Louise | President, R&D and Tech Ops | F | 895 | $16.9500 | $15.17K |
| Mar 9, 2026 | Rodino-Klapac Louise | President, R&D and Tech Ops | F | 504 | $16.9500 | $8.54K |
| Mar 9, 2026 | Wong Ryan Ho-Yan | Chief Financial Officer | F | 113 | $16.9500 | $1.92K |
| Mar 9, 2026 | Wong Ryan Ho-Yan | Chief Financial Officer | F | 162 | $16.9500 | $2.75K |
| Mar 9, 2026 | Rothfuss Cristin | EVP, General Counsel | F | 346 | $16.9500 | $5.86K |
| Mar 9, 2026 | Rothfuss Cristin | EVP, General Counsel | F | 484 | $16.9500 | $8.20K |
| Mar 2, 2026 | Rodino-Klapac Louise | President, R&D and Tech Ops | F | 767 | $16.2000 | $12.43K |
| Mar 2, 2026 | Rodino-Klapac Louise | President, R&D and Tech Ops | F | 3,718 | $16.2000 | $60.23K |
| Mar 2, 2026 | Estepan Ian Michael | Chief Operating Officer | F | 875 | $16.2000 | $14.18K |
| Mar 2, 2026 | Estepan Ian Michael | Chief Operating Officer | F | 3,301 | $16.2000 | $53.48K |
| Mar 2, 2026 | Wong Ryan Ho-Yan | Chief Financial Officer | F | 450 | $16.2000 | $7.29K |
| Mar 2, 2026 | Rothfuss Cristin | EVP, General Counsel | F | 408 | $16.2000 | $6.61K |
| Mar 1, 2026 | Rodino-Klapac Louise | President, R&D and Tech Ops | M | 8,125 | $0.0000 | $0.00 |
| Mar 1, 2026 | Rodino-Klapac Louise | President, R&D and Tech Ops | M | 8,125 | – | – |
| Mar 1, 2026 | Estepan Ian Michael | Chief Operating Officer | M | 8,125 | $0.0000 | $0.00 |
| Mar 1, 2026 | Estepan Ian Michael | Chief Operating Officer | M | 8,125 | – | – |
| Feb 26, 2026 | Estepan Ian Michael | Chief Operating Officer | M | 5,381 | $0.0000 | $0.00 |
| Feb 26, 2026 | Estepan Ian Michael | Chief Operating Officer | M | 2,069 | $0.0000 | $0.00 |
| Feb 26, 2026 | Estepan Ian Michael | Chief Operating Officer | M | 5,381 | $13.7100 | $73.77K |
| Feb 26, 2026 | Estepan Ian Michael | Chief Operating Officer | M | 2,069 | $13.7100 | $28.36K |
| Feb 25, 2026 | Rodino-Klapac Louise | President, R&D and Tech Ops | A | 1,875 | – | – |
| Feb 25, 2026 | Estepan Ian Michael | Chief Operating Officer | A | 1,875 | – | – |
| Jan 29, 2026 | Nicaise Claude | Director | M | 10,500 | $0.0000 | $0.00 |
| Jan 29, 2026 | Nicaise Claude | Director | F | 6,780 | $21.2300 | $143.94K |
| Jan 29, 2026 | Nicaise Claude | Director | M | 10,500 | $13.7100 | $143.96K |
| Jan 27, 2026 | BEHRENS M KATHLEEN | Director | M | 10,500 | $0.0000 | $0.00 |
| Jan 27, 2026 | BEHRENS M KATHLEEN | Director | F | 6,494 | $22.1700 | $143.97K |
| Jan 27, 2026 | BEHRENS M KATHLEEN | Director | M | 10,500 | $13.7100 | $143.96K |
| Dec 18, 2025 | Chambers Michael Andrew | Director | A | – | – | – |
| Dec 18, 2025 | Chambers Michael Andrew | Director | D | – | – | – |
| Dec 16, 2025 | Estepan Ian Michael | Chief Operating Officer | S | 13,187 | $22.3100 | $294.20K |
| Dec 7, 2025 | INGRAM DOUGLAS S | Chief Executive Officer | A | 269,542 | $0.0000 | $0.00 |
| Dec 7, 2025 | INGRAM DOUGLAS S | Chief Executive Officer | A | 96,541 | $0.0000 | $0.00 |
| Dec 7, 2025 | INGRAM DOUGLAS S | Chief Executive Officer | A | 73,001 | $0.0000 | $0.00 |
| Dec 7, 2025 | INGRAM DOUGLAS S | Chief Executive Officer | A | 50,000 | $0.0000 | $0.00 |