First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 11,906,646 | $85.73M | +73,107 | ↑ INC |
Bain Capital Life Sciences Investors, LLCCIK 0001703031 | 9,808,819 | $70.62M | +1,897,150 | ↑ INC |
Siren, L.L.C.CIK 0002005245 | 7,690,405 | $55.37M | – | no_change |
Vestal Point Capital, LPCIK 0001974915 | 5,000,000 | $36.00M | -815,000 | ↓ DEC |
BlackRock, Inc.CIK 0002012383 | 4,958,354 | $35.70M | +88,672 | ↑ INC |
FMR LLCCIK 0000315066 | 3,606,404 | $25.97M | +1,576,506 | ↑ INC |
Deep Track Capital, LPCIK 0001856083 | 3,565,062 | $25.67M | +3,565,062 | NEW |
ARMISTICE CAPITAL, LLCCIK 0001601086 | 3,200,000 | $23.04M | +588,000 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 2,674,624 | $19.26M | +2,674,624 | NEW |
CITADEL ADVISORS LLCCIK 0001423053 | 2,648,200 | $19.07M | -37,963 | ↓ DEC |
AMERIPRISE FINANCIAL INCCIK 0000820027 | 2,438,849 | $17.56M | +2,438,849 | NEW |
Alyeska Investment Group, L.P.CIK 0001453072 | 2,280,125 | $16.40M | +597,320 | ↑ INC |
FRANKLIN RESOURCES INCCIK 0000038777 | 2,192,937 | $15.79M | +593,704 | ↑ INC |
Point72 Asset Management, L.P.CIK 0001603466 | 2,050,843 | $14.77M | -365,265 | ↓ DEC |
Redmile Group, LLCCIK 0001425738 | 2,011,895 | $14.49M | +151,353 | ↑ INC |
Monashee Investment Management LLCCIK 0001627608 | 1,420,295 | $10.23M | +70,524 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 1,295,984 | $9.33M | +28,592 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 1,125,487 | $8.10M | +38,074 | ↑ INC |
DIMENSIONAL FUND ADVISORS LPCIK 0000354204 | 956,135 | $6.88M | +277,051 | ↑ INC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 935,535 | $6.74M | -70,771 | ↓ DEC |
Ally Bridge Group (NY) LLCCIK 0001822947 | 766,974 | $5.52M | +353,349 | ↑ INC |
BLAIR WILLIAM & CO/ILCIK 0000902367 | 651,216 | $4.69M | +485,516 | ↑ INC |
Birchview Capital, LPCIK 0001618205 | 625,980 | $4.51M | -79,975 | ↓ DEC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 575,831 | $4.15M | +61,338 | ↑ INC |
Woodline Partners LPCIK 0001784547 | 495,076 | $3.56M | +178,253 | ↑ INC |
| Filer | Δ Shares | Value |
|---|---|---|
Deep Track Capital, LPNEW | +3,565,062 | $25.67M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +2,674,624 | $19.26M |
AMERIPRISE FINANCIAL INCNEW | +2,438,849 | $17.56M |
Bain Capital Life Sciences Investors, LLC↑ INC | +1,897,150 | $70.62M |
FMR LLC↑ INC | +1,576,506 | $25.97M |
Alyeska Investment Group, L.P.↑ INC | +597,320 | $16.40M |
FRANKLIN RESOURCES INC↑ INC | +593,704 | $15.79M |
ARMISTICE CAPITAL, LLC↑ INC | +588,000 | $23.04M |
BLAIR WILLIAM & CO/IL↑ INC | +485,516 | $4.69M |
Ally Bridge Group (NY) LLC↑ INC | +353,349 | $5.52M |
| Filer | Δ Shares | Value |
|---|---|---|
Vestal Point Capital, LP↓ DEC | -815,000 | $36.00M |
UBS Group AG↓ DEC | -812,431 | $712.64K |
Point72 Asset Management, L.P.↓ DEC | -365,265 | $14.77M |
Ikarian Capital, LLC↓ DEC | -320,000 | $1.90M |
BALYASNY ASSET MANAGEMENT L.P.↓ DEC | -182,684 | $1.20M |
PANAGORA ASSET MANAGEMENT INC↓ DEC | -135,660 | $655.88K |
MORGAN STANLEY↓ DEC | -133,136 | $1.88M |
Knott David M Jr↓ DEC | -115,297 | $339.43K |
Parkman Healthcare Partners LLC↓ DEC | -109,527 | $2.22M |
BOOTHBAY FUND MANAGEMENT, LLC↓ DEC | -108,350 | $626.75K |