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Institutional Holders · 13F

First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.

Ownership

Institutions78.2%
Insiders34.0%
Institutions Count119
Institutions 78.2%Insiders 34.0%Float (Other) 0.0%
13F Filers (top 25)25Quarter 2026-03-31
Top-25 Reported Value$1.26BSum of shown holders' market value
Net Position Change10 adds · 10 trimsLargest movers this quarter

Top Holders by Value

25 shown
FilerSharesMarket ValueΔ SharesChange
TPG GP A, LLCCIK 0001903793
6,494,962$260.38M-250,000↓ DEC
ORBIMED ADVISORS LLCCIK 0001055951
3,530,702$141.55M-30,953↓ DEC
VIKING GLOBAL INVESTORS LPCIK 0001103804
3,195,181$128.09M–no_change
Atlas Venture Life Science Advisors, LLCCIK 0001917529
2,995,602$120.09M–no_change
Enavate Sciences GP, LLCCIK 0001953107
2,478,030$99.34M–no_change
JENNISON ASSOCIATES LLCCIK 0000053417
1,451,220$58.18M+335,942↑ INC
JPMORGAN CHASE & COCIK 0000019617
1,465,014$53.71M+233,195↑ INC
BlackRock, Inc.CIK 0002012383
1,295,867$51.95M+4,268↑ INC
CITADEL ADVISORS LLCCIK 0001423053
1,166,931$46.78M+79,606↑ INC
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119
1,029,497$41.27M+1,029,497NEW
DEERFIELD MANAGEMENT COMPANY, L.P.CIK 0001009258
970,590$38.91M–no_change
STATE STREET CORPCIK 0000093751
756,227$30.32M+62,832↑ INC
PERCEPTIVE ADVISORS LLCCIK 0001224962
658,439$26.40M-520,659↓ DEC
EVENTIDE ASSET MANAGEMENT, LLCCIK 0001442891
645,530$25.88M+6,485↑ INC
Aberdeen Group plcCIK 0001716774
564,175$22.62M-275,785↓ DEC
BAKER BROS. ADVISORS LPCIK 0001263508
400,000$16.04M–no_change
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717
389,872$15.63M+9,830↑ INC
Siren, L.L.C.CIK 0002005245
300,000$12.03M–no_change
Sio Capital Management, LLCCIK 0001482416
294,340$11.80M+294,340NEW
Soleus Capital Management, L.P.CIK 0001802630
293,500$11.77M+25,000↑ INC
GOLDMAN SACHS GROUP INCCIK 0000886982
263,174$10.55M+226,905↑ INC
Ensign Peak Advisors, IncCIK 0001454984
255,636$10.25M+175,774↑ INC
Candriam S.C.A.CIK 0001537014
236,813$9.49M+236,813NEW
Kalehua Capital Management LLCCIK 0002106181
197,072$7.90M–no_change
FRANKLIN RESOURCES INCCIK 0000038777
175,483$7.04M–no_change

Top Adds (Buyers)

FilerΔ SharesValue
VANGUARD CAPITAL MANAGEMENT LLCNEW
+1,029,497$41.27M
JENNISON ASSOCIATES LLC↑ INC
+335,942$58.18M
Sio Capital Management, LLCNEW
+294,340$11.80M
Candriam S.C.A.NEW
+236,813$9.49M
JPMORGAN CHASE & CO↑ INC
+233,195$53.71M
GOLDMAN SACHS GROUP INC↑ INC
+226,905$10.55M
Ensign Peak Advisors, Inc↑ INC
+175,774$10.25M
VANGUARD PORTFOLIO MANAGEMENT LLCNEW
+142,081$5.70M
Point72 Asset Management, L.P.NEW
+136,549$5.47M
GordonMD Global Investments LPNEW
+136,000$5.45M

Top Trims (Sellers)

FilerΔ SharesValue
PERCEPTIVE ADVISORS LLC↓ DEC
-520,659$26.40M
Aberdeen Group plc↓ DEC
-275,785$22.62M
TPG GP A, LLC↓ DEC
-250,000$260.38M
Invesco Ltd.↓ DEC
-100,375$432.45K
PRICE T ROWE ASSOCIATES INC /MD/↓ DEC
-74,997$30.32K
Longaeva Partners L.P.↓ DEC
-67,036$508.86K
SUPERSTRING CAPITAL MANAGEMENT LP↓ DEC
-39,569$5.65M
ORBIMED ADVISORS LLC↓ DEC
-30,953$141.55M
TD ASSET MANAGEMENT INC↓ DEC
-30,356$3.33M
BARCLAYS PLC↓ DEC
-29,787$737.06K