First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
Vivo Capital, LLCCIK 0001674712 | 11,420,000 | $43.74M | – | no_change |
Caligan Partners LPCIK 0001727492 | 7,967,207 | $30.51M | +7,967,207 | NEW |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 6,431,743 | $24.63M | +5,628,533 | ↑ INC |
Commodore Capital LPCIK 0001831942 | 4,401,500 | $16.86M | – | no_change |
BALYASNY ASSET MANAGEMENT L.P.CIK 0001218710 | 3,760,439 | $14.40M | +3,285,000 | ↑ INC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 3,032,697 | $11.62M | +2,708,607 | ↑ INC |
Woodline Partners LPCIK 0001784547 | 2,851,791 | $10.92M | +910 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 2,493,737 | $9.55M | +2,493,737 | NEW |
Spruce Street Capital LPCIK 0002050194 | 2,198,502 | $8.42M | – | no_change |
Sessa Capital IM, L.P.CIK 0001595849 | 2,198,457 | $8.42M | – | no_change |
BOOTHBAY FUND MANAGEMENT, LLCCIK 0001549230 | 1,481,660 | $5.67M | +1,481,660 | NEW |
AMERIPRISE FINANCIAL INCCIK 0000820027 | 1,476,106 | $5.65M | +1,192,461 | ↑ INC |
Ensign Peak Advisors, IncCIK 0001454984 | 1,375,610 | $5.27M | +1,375,610 | NEW |
Soleus Capital Management, L.P.CIK 0001802630 | 1,050,000 | $4.02M | +1,050,000 | NEW |
Propel Bio Management, LLCCIK 0001969764 | 1,012,790 | $3.89M | +359,909 | ↑ INC |
Jefferies Financial Group Inc.CIK 0000096223 | 903,094 | $3.46M | +322,766 | ↑ INC |
Blackstone Inc.CIK 0001393818 | 860,170 | $3.29M | -1,283,415 | ↓ DEC |
ExodusPoint Capital Management, LPCIK 0001736225 | 768,627 | $2.94M | +682,514 | ↑ INC |
Affinity Asset Advisors, LLCCIK 0001773195 | 575,000 | $2.20M | +575,000 | NEW |
Monashee Investment Management LLCCIK 0001627608 | 500,000 | $1.92M | +500,000 | NEW |
MARSHALL WACE, LLPCIK 0001318757 | 463,925 | $1.78M | +227,465 | ↑ INC |
AWM Investment Company, Inc.CIK 0001535264 | 400,000 | $1.53M | +200,000 | ↑ INC |
DV Trading LLCCIK 0001721757 | 400,000 | $1.53M | +400,000 | NEW |
STEMPOINT CAPITAL LPCIK 0001952142 | 375,000 | $1.44M | +228,442 | ↑ INC |
HB Wealth Management, LLCCIK 0001911253 | 307,500 | $1.18M | – | no_change |
| Filer | Δ Shares | Value |
|---|---|---|
Caligan Partners LPNEW | +7,967,207 | $30.51M |
PERCEPTIVE ADVISORS LLC↑ INC | +5,628,533 | $24.63M |
BALYASNY ASSET MANAGEMENT L.P.↑ INC | +3,285,000 | $14.40M |
MILLENNIUM MANAGEMENT LLC↑ INC | +2,708,607 | $11.62M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +2,493,737 | $9.55M |
BOOTHBAY FUND MANAGEMENT, LLCNEW | +1,481,660 | $5.67M |
Ensign Peak Advisors, IncNEW | +1,375,610 | $5.27M |
AMERIPRISE FINANCIAL INC↑ INC | +1,192,461 | $5.65M |
Soleus Capital Management, L.P.NEW | +1,050,000 | $4.02M |
ExodusPoint Capital Management, LP↑ INC | +682,514 | $2.94M |
| Filer | Δ Shares | Value |
|---|---|---|
Blackstone Inc.↓ DEC | -1,283,415 | $3.29M |
Simplify Asset Management Inc.↓ DEC | -20,997 | $717.09K |
OMERS ADMINISTRATION Corp↓ DEC | -12,300 | $113.75K |
Qube Research & Technologies Ltd↓ DEC | -7,049 | $92.30K |
Focus Partners Wealth↓ DEC | -5,165 | $53.76K |
JPMORGAN CHASE & CO↓ DEC | -1,903 | $329.00 |
State of Wyoming↓ DEC | -1,072 | $30.25K |