First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
FMR LLCCIK 0000315066 | 7,431,403 | $364.51M | +170,019 | ↑ INC |
Venrock Adviser, LLCCIK 0001615982 | 4,148,428 | $203.48M | – | no_change |
Fairmount Funds Management LLCCIK 0001802528 | 3,705,262 | $181.74M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 3,527,087 | $173.00M | -12,328 | ↓ DEC |
VIKING GLOBAL INVESTORS LPCIK 0001103804 | 2,666,690 | $130.80M | – | no_change |
Paradigm Biocapital Advisors LPCIK 0001855655 | 2,320,316 | $113.81M | +610,000 | ↑ INC |
RTW INVESTMENTS, LPCIK 0001493215 | 2,058,148 | $100.95M | – | no_change |
Deep Track Capital, LPCIK 0001856083 | 2,034,203 | $99.78M | -127,307 | ↓ DEC |
Remedium Capital Partners, LLCCIK 0002104501 | 1,889,115 | $92.66M | +336,701 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 1,859,631 | $91.21M | +1,859,631 | NEW |
STATE STREET CORPCIK 0000093751 | 1,613,461 | $79.14M | +229,614 | ↑ INC |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 1,395,501 | $68.45M | -81,000 | ↓ DEC |
Avidity Partners Management LPCIK 0001791827 | 760,424 | $52.02M | +100,000 | ↑ INC |
CITADEL ADVISORS LLCCIK 0001423053 | 1,018,537 | $49.96M | +292,419 | ↑ INC |
FRANKLIN RESOURCES INCCIK 0000038777 | 1,004,056 | $49.25M | +65,635 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 954,867 | $46.85M | +12,360 | ↑ INC |
MERCER GLOBAL ADVISORS INC /ADVCIK 0000853758 | 802,470 | $39.36M | +57,193 | ↑ INC |
Woodline Partners LPCIK 0001784547 | 574,882 | $28.20M | +329 | ↑ INC |
Cormorant Asset Management, LPCIK 0001583977 | 533,340 | $26.16M | – | no_change |
Bellevue Group AGCIK 0001674546 | 507,008 | $24.87M | +507,008 | NEW |
Affinity Asset Advisors, LLCCIK 0001773195 | 499,673 | $24.51M | -302,669 | ↓ DEC |
Synergy Asset Management, LLCCIK 0001699080 | 476,196 | $23.36M | +17,250 | ↑ INC |
SR ONE CAPITAL MANAGEMENT, LPCIK 0001910264 | 430,330 | $21.11M | – | no_change |
Candriam S.C.A.CIK 0001537014 | 411,006 | $20.16M | +10,497 | ↑ INC |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 350,892 | $17.21M | +350,892 | NEW |
| Filer | Δ Shares | Value |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +1,859,631 | $91.21M |
Paradigm Biocapital Advisors LP↑ INC | +610,000 | $113.81M |
Bellevue Group AGNEW | +507,008 | $24.87M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +350,892 | $17.21M |
Remedium Capital Partners, LLC↑ INC | +336,701 | $92.66M |
WESTFIELD CAPITAL MANAGEMENT CO LPNEW | +313,130 | $15.36M |
CITADEL ADVISORS LLC↑ INC | +292,419 | $49.96M |
VANGUARD FIDUCIARY TRUST CONEW | +257,071 | $12.61M |
Atika Capital Management LLCNEW | +229,900 | $11.28M |
STATE STREET CORP↑ INC | +229,614 | $79.14M |
| Filer | Δ Shares | Value |
|---|---|---|
Affinity Asset Advisors, LLC↓ DEC | -302,669 | $24.51M |
Cable Car Capital, LP↓ DEC | -200,000 | $9.81M |
Soleus Capital Management, L.P.↓ DEC | -185,000 | $245.25K |
Deep Track Capital, LP↓ DEC | -127,307 | $99.78M |
BARCLAYS PLC↓ DEC | -87,592 | $4.21M |
PERCEPTIVE ADVISORS LLC↓ DEC | -81,000 | $68.45M |
UBS Group AG↓ DEC | -58,742 | $10.41M |
Invesco Ltd.↓ DEC | -46,079 | $4.76M |
BANK OF AMERICA CORP /DE/↓ DEC | -39,181 | $4.91M |
SILVERARC CAPITAL MANAGEMENT, LLC↓ DEC | -14,481 | $7.40M |