| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 18, 2026 | Bumol Thomas F. | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 18, 2026 | Cable Thomas J. | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 18, 2026 | Demopulos Peter A MD | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 18, 2026 | HANISH ARNOLD C | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 18, 2026 | Shah Rajiv | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 18, 2026 | Hood Leroy E. MD PhD | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 18, 2026 | Perkinson Diana T. | Director | A | 15,000 | $0.0000 | $0.00 |
| May 22, 2026 | Cable Thomas J. | Director | M | 7,500 | $0.0000 | $0.00 |
| May 22, 2026 | Cable Thomas J. | Director | S | 7,500 | $11.6052 | $87.04K |
| May 22, 2026 | Cable Thomas J. | Director | M | 7,500 | $10.8400 | $81.30K |
| Feb 18, 2026 | Demopulos Gregory A MD | Chairman, CEO & President | M | 400,000 | $0.0000 | $0.00 |
| Feb 18, 2026 | Demopulos Gregory A MD | Chairman, CEO & President | F | 357,678 | $11.9300 | $4.27M |
| Feb 18, 2026 | Demopulos Gregory A MD | Chairman, CEO & President | M | 400,000 | $10.2700 | $4.11M |
| Jan 13, 2026 | Borges David J. | VP, Finance & CAO | M | 30,000 | $0.0000 | $0.00 |
| Jan 13, 2026 | Borges David J. | VP, Finance & CAO | S | 30,000 | $12.3105 | $369.31K |
| Jan 13, 2026 | Borges David J. | VP, Finance & CAO | M | 30,000 | $3.0600 | $91.80K |
| Jan 12, 2026 | Borges David J. | VP, Finance & CAO | S | 30,000 | $12.7200 | $381.60K |
| Oct 13, 2025 | Demopulos Gregory A MD | Chairman, CEO & President | G | 300,000 | $0.0000 | $0.00 |
| Oct 13, 2025 | Demopulos Gregory A MD | Chairman, CEO & President | G | 300,000 | $0.0000 | $0.00 |
| Oct 13, 2025 | Demopulos Gregory A MD | Chairman, CEO & President | G | 600,000 | $0.0000 | $0.00 |
| Jun 30, 2025 | Borges David J. | VP, Finance & CAO | A | 95,000 | $0.0000 | $0.00 |
| Jun 30, 2025 | Cancelmo Peter B | VP, General Counsel | A | 100,000 | $0.0000 | $0.00 |
| Jun 30, 2025 | Demopulos Gregory A MD | Chairman, CEO & President | A | 865,000 | $0.0000 | $0.00 |
| Jun 27, 2025 | Bumol Thomas F. | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 27, 2025 | Cable Thomas J. | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 27, 2025 | Demopulos Peter A MD | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 27, 2025 | HANISH ARNOLD C | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 27, 2025 | Hood Leroy E. MD PhD | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 27, 2025 | Perkinson Diana T. | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 27, 2025 | Shah Rajiv | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 6, 2024 | Bumol Thomas F. | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 6, 2024 | Cable Thomas J. | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 6, 2024 | Demopulos Peter A MD | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 6, 2024 | HANISH ARNOLD C | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 6, 2024 | Hood Leroy E. MD PhD | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 6, 2024 | Perkinson Diana T. | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 6, 2024 | Shah Rajiv | Director | A | 15,000 | $0.0000 | $0.00 |
| Apr 25, 2024 | Cancelmo Peter B | VP, General Counsel | A | 100,000 | $0.0000 | $0.00 |
| Apr 25, 2024 | JACOBSEN MICHAEL A | VP, Finance & CAO | A | 100,000 | $0.0000 | $0.00 |
| Apr 25, 2024 | Demopulos Gregory A MD | Chairman, CEO & President | A | 725,000 | $0.0000 | $0.00 |
| Nov 17, 2023 | Demopulos Gregory A MD | Chairman, CEO & President | P | 15,000 | $1.6800 | $25.20K |
| Nov 15, 2023 | Demopulos Peter A MD | Director | P | 10,000 | $1.5300 | $15.30K |
| Nov 14, 2023 | Demopulos Gregory A MD | Chairman, CEO & President | A | 25,000 | $1.4400 | $36.00K |
| Nov 13, 2023 | Demopulos Gregory A MD | Chairman, CEO & President | A | 37,500 | $1.2900 | $48.38K |
| Sep 22, 2023 | Cancelmo Peter B | VP, General Counsel | A | 100,000 | $0.0000 | $0.00 |
| Sep 22, 2023 | JACOBSEN MICHAEL A | VP, Finance & CAO | A | 100,000 | $0.0000 | $0.00 |
| Sep 22, 2023 | Demopulos Gregory A MD | Chairman, CEO & President | A | 715,000 | $0.0000 | $0.00 |
| Sep 12, 2023 | Bumol Thomas F. | Director | A | 10,000 | $3.3100 | $33.10K |
| Jun 23, 2023 | Cable Thomas J. | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 23, 2023 | Bumol Thomas F. | Director | A | 15,000 | $0.0000 | $0.00 |