| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 16, 2026 | Dugel Pravin | See Remarks | G | 50,092 | $0.0000 | $0.00 |
| Jun 16, 2026 | Dugel Pravin | See Remarks | G | 50,092 | $0.0000 | $0.00 |
| Jun 10, 2026 | RAINES MERILEE | Director | A | 44,000 | $0.0000 | $0.00 |
| Jun 10, 2026 | RAINES MERILEE | Director | A | 14,000 | $0.0000 | $0.00 |
| Jun 10, 2026 | Williams Leslie J. | Director | A | 44,000 | $0.0000 | $0.00 |
| Jun 10, 2026 | Williams Leslie J. | Director | A | 14,000 | $0.0000 | $0.00 |
| Jun 10, 2026 | LINDSTROM RICHARD L MD | Director | A | 44,000 | $0.0000 | $0.00 |
| Jun 10, 2026 | LINDSTROM RICHARD L MD | Director | A | 14,000 | $0.0000 | $0.00 |
| Jun 10, 2026 | Hong Seung Suh | Director | A | 44,000 | $0.0000 | $0.00 |
| Jun 10, 2026 | Hong Seung Suh | Director | A | 14,000 | $0.0000 | $0.00 |
| Jun 10, 2026 | Graves Adrienne L | Director | A | 44,000 | $0.0000 | $0.00 |
| Jun 10, 2026 | Graves Adrienne L | Director | A | 14,000 | $0.0000 | $0.00 |
| Jun 10, 2026 | Robins Jason Shand | Chief Financial Officer | A | 14,024 | $0.0000 | $0.00 |
| Jun 10, 2026 | Robins Jason Shand | Chief Financial Officer | A | 15,441 | $0.0000 | $0.00 |
| Jun 10, 2026 | Warden Charles M | Director | A | 44,000 | $0.0000 | $0.00 |
| Jun 10, 2026 | Warden Charles M | Director | A | 14,000 | $0.0000 | $0.00 |
| Jun 3, 2026 | Waheed Nadia | Chief Medical Officer | S | 14,828 | $8.2700 | $122.63K |
| May 28, 2026 | Dugel Pravin | See Remarks | G | 394,696 | $0.0000 | $0.00 |
| May 28, 2026 | Dugel Pravin | See Remarks | G | 394,696 | $0.0000 | $0.00 |
| May 26, 2026 | Nayak Sanjay | Chief Strategy Officer | S | 1,858 | $8.2000 | $15.23K |
| May 26, 2026 | Heier Jeffrey S. | Chief Scientific Officer | S | 3,018 | $8.2000 | $24.75K |
| May 26, 2026 | Kaiser Peter | Chief Development Officer | S | 2,967 | $8.2000 | $24.33K |
| May 26, 2026 | Dugel Pravin | See Remarks | S | 21,156 | $8.2000 | $173.48K |
| Apr 9, 2026 | Dugel Pravin | See Remarks | G | 394,696 | $0.0000 | $0.00 |
| Apr 9, 2026 | Dugel Pravin | See Remarks | G | 394,696 | $0.0000 | $0.00 |
| Feb 23, 2026 | Nayak Sanjay | Chief Strategy Officer | S | 1,759 | $8.2800 | $14.56K |
| Feb 23, 2026 | Heier Jeffrey S. | Chief Scientific Officer | S | 3,057 | $8.2800 | $25.31K |
| Feb 23, 2026 | Kaiser Peter | Chief Development Officer | S | 2,810 | $8.2800 | $23.27K |
| Feb 23, 2026 | Dugel Pravin | See Remarks | S | 20,056 | $8.2800 | $166.06K |
| Feb 20, 2026 | LINDSTROM RICHARD L MD | Director | P | 60,229 | $7.6600 | $461.35K |
| Feb 20, 2026 | Waheed Nadia | Chief Medical Officer | S | 3,510 | $7.7400 | $27.17K |
| Feb 12, 2026 | Waheed Nadia | Chief Medical Officer | S | 7,863 | $9.0400 | $71.08K |
| Feb 12, 2026 | Dugel Pravin | See Remarks | S | 124,882 | $9.0400 | $1.13M |
| Feb 12, 2026 | Nayak Sanjay | Chief Strategy Officer | S | 10,348 | $9.0400 | $93.55K |
| Feb 12, 2026 | Notman Donald | Chief Operating Officer | S | 11,446 | $9.0400 | $103.47K |
| Feb 4, 2026 | Notman Donald | Chief Operating Officer | S | 6,035 | $8.5400 | $51.54K |
| Feb 2, 2026 | Notman Donald | Chief Operating Officer | S | 5,455 | $9.1400 | $49.86K |
| Jan 21, 2026 | Robinson David Wayne | Global CCO | A | 416,000 | $0.0000 | $0.00 |
| Jan 21, 2026 | Robinson David Wayne | Global CCO | A | 136,000 | $0.0000 | $0.00 |
| Jan 20, 2026 | Robins Jason Shand | Interim CFO | A | 33,000 | $0.0000 | $0.00 |
| Jan 2, 2026 | Notman Donald | See Remarks | A | 240,932 | $0.0000 | $0.00 |
| Jan 2, 2026 | Notman Donald | See Remarks | A | 79,112 | $0.0000 | $0.00 |
| Jan 2, 2026 | Heier Jeffrey S. | Chief Scientific Officer | A | 240,932 | $0.0000 | $0.00 |
| Jan 2, 2026 | Heier Jeffrey S. | Chief Scientific Officer | A | 79,112 | $0.0000 | $0.00 |
| Jan 2, 2026 | Waheed Nadia | Chief Medical Officer | A | 240,932 | $0.0000 | $0.00 |
| Jan 2, 2026 | Waheed Nadia | Chief Medical Officer | A | 79,112 | $0.0000 | $0.00 |
| Jan 2, 2026 | Saroj Namrata | Chief Business Officer | A | 240,932 | $0.0000 | $0.00 |
| Jan 2, 2026 | Saroj Namrata | Chief Business Officer | A | 79,112 | $0.0000 | $0.00 |
| Jan 2, 2026 | Kaiser Peter | Chief Development Officer | A | 240,932 | $0.0000 | $0.00 |
| Jan 2, 2026 | Kaiser Peter | Chief Development Officer | A | 79,112 | $0.0000 | $0.00 |