| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 9, 2026 | Delaet Ingrid | Chief Regulatory Officer | M | 8,433 | $0.0000 | $0.00 |
| Jul 9, 2026 | Delaet Ingrid | Chief Regulatory Officer | S | 8,433 | $178.7187 | $1.51M |
| Jul 9, 2026 | Delaet Ingrid | Chief Regulatory Officer | M | 8,433 | $103.5200 | $872.98K |
| Jul 8, 2026 | Delaet Ingrid | Chief Regulatory Officer | M | 2,737 | $0.0000 | $0.00 |
| Jul 8, 2026 | Delaet Ingrid | Chief Regulatory Officer | S | 2,737 | $178.5430 | $488.67K |
| Jul 8, 2026 | Delaet Ingrid | Chief Regulatory Officer | M | 2,737 | $103.5200 | $283.33K |
| Jul 7, 2026 | Delaet Ingrid | Chief Regulatory Officer | M | 3,401 | $0.0000 | $0.00 |
| Jul 7, 2026 | Delaet Ingrid | Chief Regulatory Officer | S | 3,401 | $178.5666 | $607.30K |
| Jul 7, 2026 | Delaet Ingrid | Chief Regulatory Officer | M | 3,401 | $103.5200 | $352.07K |
| Jun 29, 2026 | Lippoldt Darin | Chief Legal Officer | M | 1,690 | $0.0000 | $0.00 |
| Jun 29, 2026 | Lippoldt Darin | Chief Legal Officer | M | 8,110 | $0.0000 | $0.00 |
| Jun 29, 2026 | Lippoldt Darin | Chief Legal Officer | S | 1,690 | $170.8144 | $288.68K |
| Jun 29, 2026 | Lippoldt Darin | Chief Legal Officer | M | 1,690 | $81.4900 | $137.72K |
| Jun 29, 2026 | Lippoldt Darin | Chief Legal Officer | S | 8,110 | $170.0250 | $1.38M |
| Jun 29, 2026 | Lippoldt Darin | Chief Legal Officer | M | 8,110 | $81.4900 | $660.88K |
| Jun 26, 2026 | Lippoldt Darin | Chief Legal Officer | M | 200 | $0.0000 | $0.00 |
| Jun 26, 2026 | Lippoldt Darin | Chief Legal Officer | S | 200 | $169.5650 | $33.91K |
| Jun 26, 2026 | Lippoldt Darin | Chief Legal Officer | M | 200 | $81.4900 | $16.30K |
| Jun 5, 2026 | Onyia Jude | Chief Scientific Officer | G | 2,441 | $0.0000 | $0.00 |
| Jun 5, 2026 | SHERWIN STEPHEN A | Director | M | 10,000 | $0.0000 | $0.00 |
| Jun 5, 2026 | SHERWIN STEPHEN A | Director | M | 15,000 | $0.0000 | $0.00 |
| Jun 5, 2026 | SHERWIN STEPHEN A | Director | S | 1,843 | $167.3128 | $308.36K |
| Jun 5, 2026 | SHERWIN STEPHEN A | Director | S | 5,829 | $166.5567 | $970.86K |
| Jun 5, 2026 | SHERWIN STEPHEN A | Director | S | 6,896 | $165.7926 | $1.14M |
| Jun 5, 2026 | SHERWIN STEPHEN A | Director | S | 2,549 | $164.4394 | $419.16K |
| Jun 5, 2026 | SHERWIN STEPHEN A | Director | S | 7,883 | $163.8070 | $1.29M |
| Jun 5, 2026 | SHERWIN STEPHEN A | Director | M | 10,000 | $79.7900 | $797.90K |
| Jun 5, 2026 | SHERWIN STEPHEN A | Director | M | 15,000 | $53.6400 | $804.60K |
| Jun 4, 2026 | Norwalk Leslie V | Director | S | 1,250 | $168.0573 | $210.07K |
| Jun 2, 2026 | Keswani Sanjay Chandru | Chief Medical Officer | M | 3,212 | $0.0000 | $0.00 |
| Jun 2, 2026 | Keswani Sanjay Chandru | Chief Medical Officer | F | 1,733 | $154.8400 | $268.34K |
| Jun 2, 2026 | Keswani Sanjay Chandru | Chief Medical Officer | M | 3,212 | $0.0000 | $0.00 |
| Jun 2, 2026 | Cooke Julie | Chief Human Resources Officer | M | 24,965 | $0.0000 | $0.00 |
| Jun 2, 2026 | Cooke Julie | Chief Human Resources Officer | S | 3,520 | $158.5897 | $558.24K |
| Jun 2, 2026 | Cooke Julie | Chief Human Resources Officer | S | 9,521 | $157.6161 | $1.50M |
| Jun 2, 2026 | Cooke Julie | Chief Human Resources Officer | S | 4,216 | $156.7660 | $660.92K |
| Jun 2, 2026 | Cooke Julie | Chief Human Resources Officer | S | 5,466 | $155.4566 | $849.73K |
| Jun 2, 2026 | Cooke Julie | Chief Human Resources Officer | S | 14,214 | $154.8252 | $2.20M |
| Jun 2, 2026 | Cooke Julie | Chief Human Resources Officer | M | 24,965 | $81.4900 | $2.03M |
| Jun 1, 2026 | Onyia Jude | Chief Scientific Officer | M | 11,000 | $0.0000 | $0.00 |
| Jun 1, 2026 | Onyia Jude | Chief Scientific Officer | S | 11,000 | $160.2464 | $1.76M |
| Jun 1, 2026 | Onyia Jude | Chief Scientific Officer | M | 11,000 | $84.7400 | $932.14K |
| May 29, 2026 | Delaet Ingrid | Chief Regulatory Officer | M | 2,261 | $0.0000 | $0.00 |
| May 29, 2026 | Delaet Ingrid | Chief Regulatory Officer | S | 2,261 | $156.7100 | $354.32K |
| May 29, 2026 | Delaet Ingrid | Chief Regulatory Officer | M | 2,261 | $79.0200 | $178.66K |
| May 27, 2026 | Norwalk Leslie V | Director | A | 2,624 | $0.0000 | $0.00 |
| May 27, 2026 | Norwalk Leslie V | Director | A | 1,284 | $0.0000 | $0.00 |
| May 27, 2026 | RASTETTER WILLIAM H | Director | A | 2,567 | $0.0000 | $0.00 |
| May 27, 2026 | SHERWIN STEPHEN A | Director | A | 2,567 | $0.0000 | $0.00 |
| May 27, 2026 | MORROW GEORGE J | Director | A | 2,567 | $0.0000 | $0.00 |