| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 22, 2026 | Kooij Louise Frederika | Chief Accounting Officer | M | 15,000 | $0.0000 | $0.00 |
| Jun 22, 2026 | Kooij Louise Frederika | Chief Accounting Officer | M | 25,000 | $0.0000 | $0.00 |
| Jun 22, 2026 | Kooij Louise Frederika | Chief Accounting Officer | S | 300 | $30.7300 | $9.22K |
| Jun 22, 2026 | Kooij Louise Frederika | Chief Accounting Officer | S | 39,700 | $30.2000 | $1.20M |
| Jun 22, 2026 | Kooij Louise Frederika | Chief Accounting Officer | M | 15,000 | $11.9000 | $178.50K |
| Jun 22, 2026 | Kooij Louise Frederika | Chief Accounting Officer | M | 25,000 | $10.9000 | $272.50K |
| May 26, 2026 | Kooij Louise Frederika | Chief Accounting Officer | M | 5,000 | $0.0000 | $0.00 |
| May 26, 2026 | Kooij Louise Frederika | Chief Accounting Officer | M | 60,000 | $0.0000 | $0.00 |
| May 26, 2026 | Kooij Louise Frederika | Chief Accounting Officer | S | 65,000 | $35.6900 | $2.32M |
| May 26, 2026 | Kooij Louise Frederika | Chief Accounting Officer | M | 5,000 | $10.9000 | $54.50K |
| May 26, 2026 | Kooij Louise Frederika | Chief Accounting Officer | M | 60,000 | $10.0000 | $600.00K |
| Mar 11, 2026 | LANGE LOUIS G | Director | S | 446 | $31.2300 | $13.93K |
| Mar 11, 2026 | LANGE LOUIS G | Director | S | 44,173 | $30.4100 | $1.34M |
| Mar 9, 2026 | Kastelein Johannes Jacob Pieter | Chief Scientific Officer | M | 101,409 | $0.0000 | $0.00 |
| Mar 9, 2026 | Kastelein Johannes Jacob Pieter | Chief Scientific Officer | S | 101,409 | $30.2900 | $3.07M |
| Mar 9, 2026 | Kastelein Johannes Jacob Pieter | Chief Scientific Officer | M | 101,409 | – | – |
| Mar 9, 2026 | LANGE LOUIS G | Director | X | 44,619 | $0.0000 | $0.00 |
| Mar 9, 2026 | LANGE LOUIS G | Director | X | 44,619 | $11.5000 | $513.12K |
| Mar 6, 2026 | Kastelein Johannes Jacob Pieter | Chief Scientific Officer | M | 94,124 | $0.0000 | $0.00 |
| Mar 6, 2026 | Kastelein Johannes Jacob Pieter | Chief Scientific Officer | S | 94,124 | $30.3200 | $2.85M |
| Mar 6, 2026 | Kastelein Johannes Jacob Pieter | Chief Scientific Officer | M | 94,124 | – | – |
| Mar 6, 2026 | LANGE LOUIS G | Director | S | 28,186 | $29.4100 | $828.95K |
| Mar 5, 2026 | Kastelein Johannes Jacob Pieter | Chief Scientific Officer | M | 104,467 | $0.0000 | $0.00 |
| Mar 5, 2026 | Kastelein Johannes Jacob Pieter | Chief Scientific Officer | S | 104,467 | $30.3000 | $3.17M |
| Mar 5, 2026 | Kastelein Johannes Jacob Pieter | Chief Scientific Officer | M | 104,467 | – | – |
| Mar 2, 2026 | Davidson Michael H. | Chief Executive Officer | M | 443,707 | $0.0000 | $0.00 |
| Mar 2, 2026 | Davidson Michael H. | Chief Executive Officer | S | 443,707 | $33.2500 | $14.75M |
| Mar 2, 2026 | Davidson Michael H. | Chief Executive Officer | M | 443,707 | – | – |
| Feb 26, 2026 | Davidson Michael H. | Chief Executive Officer | M | 183,332 | $0.0000 | $0.00 |
| Feb 26, 2026 | Davidson Michael H. | Chief Executive Officer | S | 17,924 | $34.4400 | $617.30K |
| Feb 26, 2026 | Davidson Michael H. | Chief Executive Officer | S | 165,408 | $33.6300 | $5.56M |
| Feb 26, 2026 | Davidson Michael H. | Chief Executive Officer | M | 183,332 | – | – |
| Feb 25, 2026 | Davidson Michael H. | Chief Executive Officer | M | 58,253 | $0.0000 | $0.00 |
| Feb 25, 2026 | Davidson Michael H. | Chief Executive Officer | S | 1,300 | $36.6800 | $47.68K |
| Feb 25, 2026 | Davidson Michael H. | Chief Executive Officer | S | 10,436 | $35.9600 | $375.28K |
| Feb 25, 2026 | Davidson Michael H. | Chief Executive Officer | S | 46,517 | $35.1100 | $1.63M |
| Feb 25, 2026 | Davidson Michael H. | Chief Executive Officer | M | 58,253 | – | – |
| Feb 24, 2026 | Davidson Michael H. | Chief Executive Officer | M | 64,708 | $0.0000 | $0.00 |
| Feb 24, 2026 | Davidson Michael H. | Chief Executive Officer | S | 3,161 | $36.4600 | $115.25K |
| Feb 24, 2026 | Davidson Michael H. | Chief Executive Officer | S | 61,547 | $36.1300 | $2.22M |
| Feb 24, 2026 | Davidson Michael H. | Chief Executive Officer | M | 64,708 | – | – |
| Feb 20, 2026 | Kastelein Johannes Jacob Pieter | Chief Scientific Officer | S | 30,789 | $35.4600 | $1.09M |
| Feb 20, 2026 | Kastelein Johannes Jacob Pieter | Chief Scientific Officer | S | 14,692 | $35.0000 | $514.22K |
| Jan 28, 2026 | Kooij Louise Frederika | Chief Accounting Officer | M | 32,612 | $0.0000 | $0.00 |
| Jan 28, 2026 | Kooij Louise Frederika | Chief Accounting Officer | S | 32,612 | $31.8000 | $1.04M |
| Jan 28, 2026 | Kooij Louise Frederika | Chief Accounting Officer | M | 32,612 | $10.9000 | $355.47K |
| Jan 27, 2026 | Kooij Louise Frederika | Chief Accounting Officer | M | 39,816 | $0.0000 | $0.00 |
| Jan 27, 2026 | Kooij Louise Frederika | Chief Accounting Officer | S | 39,816 | $32.6200 | $1.30M |
| Jan 27, 2026 | Kooij Louise Frederika | Chief Accounting Officer | M | 39,816 | $10.9000 | $433.99K |
| Jan 26, 2026 | Kooij Louise Frederika | Chief Accounting Officer | M | 34,400 | $0.0000 | $0.00 |