| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| May 20, 2026 | Tross Stuart A | Chief People & Workpl Officer | A | 33,898 | $2.9500 | $100.00K |
| May 20, 2026 | Kay Sabrina | Director | A | 82,781 | $0.0000 | $0.00 |
| May 20, 2026 | MUNDKUR CHRISTINE | Director | A | 82,781 | $0.0000 | $0.00 |
| May 20, 2026 | Marasco Dominic | Pres, Endocrine Business Unit | A | 8,474 | $2.9500 | $25.00K |
| May 20, 2026 | Shannon James Samuel | Director | A | 16,556 | $0.0000 | $0.00 |
| May 20, 2026 | Shannon James Samuel | Director | A | 82,781 | $0.0000 | $0.00 |
| May 20, 2026 | HOOPER ANTHONY C | Director | A | 16,556 | $0.0000 | $0.00 |
| May 20, 2026 | HOOPER ANTHONY C | Director | A | 82,781 | $0.0000 | $0.00 |
| May 20, 2026 | Grancio Jennifer | Director | A | 82,781 | $0.0000 | $0.00 |
| May 20, 2026 | Binder Steven B. | Director | A | 82,781 | $0.0000 | $0.00 |
| May 20, 2026 | Consiglio Ronald J | Director | A | 16,556 | $0.0000 | $0.00 |
| May 20, 2026 | Consiglio Ronald J | Director | A | 82,781 | $0.0000 | $0.00 |
| May 20, 2026 | Consiglio Ronald J | Director | A | 10,000 | $2.9500 | $29.50K |
| May 20, 2026 | Friedman Michael A | Director | A | 82,781 | $0.0000 | $0.00 |
| May 12, 2026 | Thomson David | EVP Genl Counsel & Secretary | S | 3,033 | $3.2900 | $9.98K |
| May 12, 2026 | Binder Steven B. | Director | S | 16,940 | $3.2900 | $55.73K |
| May 11, 2026 | Thomson David | EVP Genl Counsel & Secretary | F | 12,387 | $3.5200 | $43.60K |
| May 11, 2026 | Binder Steven B. | Director | F | 5,560 | $3.5200 | $19.57K |
| May 11, 2026 | Castagna Michael | Chief Executive Officer | F | 34,957 | $3.5200 | $123.05K |
| May 11, 2026 | Tross Stuart A | Chief People & Workpl Officer | F | 8,073 | $3.5200 | $28.42K |
| Apr 22, 2026 | Prentiss Christopher B | Chief Financial Officer | F | 12,267 | $2.7400 | $33.61K |
| Mar 23, 2026 | Prentiss Christopher B | Chief Financial Officer | A | 217,000 | $0.0000 | $0.00 |
| Mar 23, 2026 | Prentiss Christopher B | Chief Financial Officer | A | 221,000 | $0.0000 | $0.00 |
| Mar 23, 2026 | Castagna Michael | Chief Executive Officer | A | 782,000 | $0.0000 | $0.00 |
| Mar 23, 2026 | Castagna Michael | Chief Executive Officer | A | 796,000 | $0.0000 | $0.00 |
| Mar 23, 2026 | Singh Sanjay R | EVP Technical Operations | A | 217,000 | $0.0000 | $0.00 |
| Mar 23, 2026 | Singh Sanjay R | EVP Technical Operations | A | 221,000 | $0.0000 | $0.00 |
| Mar 23, 2026 | Tross Stuart A | Chief People & Workpl Officer | A | 217,000 | $0.0000 | $0.00 |
| Mar 23, 2026 | Tross Stuart A | Chief People & Workpl Officer | A | 221,000 | $0.0000 | $0.00 |
| Mar 23, 2026 | Thomson David | EVP Genl Counsel & Secretary | A | 217,000 | $0.0000 | $0.00 |
| Mar 23, 2026 | Thomson David | EVP Genl Counsel & Secretary | A | 221,000 | $0.0000 | $0.00 |
| Mar 23, 2026 | Ahuja Ajay | Chief Medical Officer | A | 217,000 | $0.0000 | $0.00 |
| Mar 23, 2026 | Ahuja Ajay | Chief Medical Officer | A | 221,000 | $0.0000 | $0.00 |
| Mar 10, 2026 | Castagna Michael | Chief Executive Officer | P | 100,000 | $2.5900 | $259.00K |
| Mar 1, 2026 | Tross Stuart A | Chief People & Workpl Officer | A | 15,290 | $3.2700 | $50.00K |
| Mar 1, 2026 | Castagna Michael | Chief Executive Officer | A | 15,290 | $3.2700 | $50.00K |
| Mar 1, 2026 | Prentiss Christopher B | Chief Financial Officer | A | 5,000 | $3.2700 | $16.35K |
| Mar 1, 2026 | HOOPER ANTHONY C | Director | A | 35,000 | $3.2700 | $114.45K |
| Mar 1, 2026 | Shannon James Samuel | Director | A | 12,000 | $3.2700 | $39.24K |
| Feb 26, 2026 | Tross Stuart A | Chief People & Workpl Officer | A | 28,143 | $0.0000 | $0.00 |
| Feb 26, 2026 | Tross Stuart A | Chief People & Workpl Officer | A | 20,000 | $0.0000 | $0.00 |
| Feb 26, 2026 | Binder Steven B. | Director | A | 45,025 | $0.0000 | $0.00 |
| Feb 26, 2026 | Thomson David | EVP Genl Counsel & Secretary | A | 37,525 | $0.0000 | $0.00 |
| Feb 26, 2026 | Thomson David | EVP Genl Counsel & Secretary | A | 20,000 | $0.0000 | $0.00 |
| Feb 26, 2026 | Castagna Michael | Chief Executive Officer | A | 37,525 | $0.0000 | $0.00 |
| Feb 26, 2026 | Castagna Michael | Chief Executive Officer | A | 57,750 | $0.0000 | $0.00 |
| Feb 26, 2026 | Castagna Michael | Chief Executive Officer | A | 50,000 | $0.0000 | $0.00 |
| Jan 8, 2026 | Tross Stuart A | Chief People & Workpl Officer | S | 47,006 | $6.3300 | $297.55K |
| Dec 24, 2025 | Castagna Michael | Chief Executive Officer | G | 44,171 | $0.0000 | $0.00 |
| Dec 17, 2025 | Castagna Michael | Chief Executive Officer | M | 50,000 | $0.0000 | $0.00 |