| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 1, 2026 | Malkani Dhiraj H | CHIEF STRATEGY OFFICER | A | 1,307 | $0.0000 | $0.00 |
| Jul 1, 2026 | Malkani Dhiraj H | CHIEF STRATEGY OFFICER | A | 1,245 | $0.0000 | $0.00 |
| Jul 1, 2026 | Malkani Dhiraj H | CHIEF STRATEGY OFFICER | A | 2,188 | $0.0000 | $0.00 |
| Jul 1, 2026 | Malkani Dhiraj H | CHIEF STRATEGY OFFICER | A | 2,119 | $0.0000 | $0.00 |
| Jul 1, 2026 | Malkani Dhiraj H | CHIEF STRATEGY OFFICER | A | 14,000 | $0.0000 | $0.00 |
| Jul 1, 2026 | Malkani Dhiraj H | CHIEF STRATEGY OFFICER | A | 82,600 | $0.0000 | $0.00 |
| Jun 1, 2026 | Patel Sanj K | CHAIRMAN & CEO | C | 900,000 | $0.0000 | $0.00 |
| Jun 1, 2026 | Patel Sanj K | CHAIRMAN & CEO | C | 900,000 | – | – |
| May 29, 2026 | BAKER BROS. ADVISORS LP | Director | A | 36,474 | $0.0000 | $0.00 |
| May 29, 2026 | BAKER BROS. ADVISORS LP | Director | A | 36,474 | $0.0000 | $0.00 |
| May 29, 2026 | BAKER BROS. ADVISORS LP | Director | A | 6,078 | $0.0000 | $0.00 |
| May 29, 2026 | BAKER BROS. ADVISORS LP | Director | A | 6,078 | $0.0000 | $0.00 |
| May 29, 2026 | Cole G Bradley | Director | M | 2,799 | $0.0000 | $0.00 |
| May 29, 2026 | Cole G Bradley | Director | A | 2,026 | $0.0000 | $0.00 |
| May 29, 2026 | Cole G Bradley | Director | A | 12,158 | $0.0000 | $0.00 |
| May 29, 2026 | Cole G Bradley | Director | M | 2,799 | – | – |
| May 29, 2026 | Levy Richard S | Director | M | 2,799 | $0.0000 | $0.00 |
| May 29, 2026 | Levy Richard S | Director | A | 2,026 | $0.0000 | $0.00 |
| May 29, 2026 | Levy Richard S | Director | A | 12,158 | $0.0000 | $0.00 |
| May 29, 2026 | Levy Richard S | Director | M | 2,799 | – | – |
| May 29, 2026 | Malley Thomas | Director | M | 2,799 | $0.0000 | $0.00 |
| May 29, 2026 | Malley Thomas | Director | A | 2,026 | $0.0000 | $0.00 |
| May 29, 2026 | Malley Thomas | Director | A | 12,158 | $0.0000 | $0.00 |
| May 29, 2026 | Malley Thomas | Director | M | 2,799 | – | – |
| May 29, 2026 | McCain Tracey L | Director | M | 2,799 | $0.0000 | $0.00 |
| May 29, 2026 | McCain Tracey L | Director | A | 2,026 | $0.0000 | $0.00 |
| May 29, 2026 | McCain Tracey L | Director | A | 12,158 | $0.0000 | $0.00 |
| May 29, 2026 | McCain Tracey L | Director | M | 2,799 | – | – |
| May 29, 2026 | Popovits Kimberly J | Director | M | 2,799 | $0.0000 | $0.00 |
| May 29, 2026 | Popovits Kimberly J | Director | A | 2,026 | $0.0000 | $0.00 |
| May 29, 2026 | Popovits Kimberly J | Director | A | 12,158 | $0.0000 | $0.00 |
| May 29, 2026 | Popovits Kimberly J | Director | M | 2,799 | – | – |
| May 29, 2026 | Quart Barry D | Director | M | 2,799 | $0.0000 | $0.00 |
| May 29, 2026 | Quart Barry D | Director | A | 2,026 | $0.0000 | $0.00 |
| May 29, 2026 | Quart Barry D | Director | A | 12,158 | $0.0000 | $0.00 |
| May 29, 2026 | Quart Barry D | Director | M | 2,799 | – | – |
| May 1, 2026 | Patel Sanj K | CHAIRMAN & CEO | M | 48,565 | $0.0000 | $0.00 |
| May 1, 2026 | Patel Sanj K | CHAIRMAN & CEO | S | 48,565 | $54.0200 | $2.62M |
| May 1, 2026 | Patel Sanj K | CHAIRMAN & CEO | M | 48,565 | $30.9300 | $1.50M |
| May 1, 2026 | Paolini John F. | CHIEF MEDICAL OFFICER | M | 58,424 | $0.0000 | $0.00 |
| May 1, 2026 | Paolini John F. | CHIEF MEDICAL OFFICER | S | 21,097 | $54.0400 | $1.14M |
| May 1, 2026 | Paolini John F. | CHIEF MEDICAL OFFICER | S | 37,327 | $53.5200 | $2.00M |
| May 1, 2026 | Paolini John F. | CHIEF MEDICAL OFFICER | M | 58,424 | $10.3600 | $605.27K |
| Apr 30, 2026 | Patel Sanj K | CHAIRMAN & CEO | M | 2,141 | $0.0000 | $0.00 |
| Apr 30, 2026 | Patel Sanj K | CHAIRMAN & CEO | S | 2,141 | $54.0100 | $115.64K |
| Apr 30, 2026 | Patel Sanj K | CHAIRMAN & CEO | M | 2,141 | $30.9300 | $66.22K |
| Apr 29, 2026 | Patel Sanj K | CHAIRMAN & CEO | M | 22,544 | $0.0000 | $0.00 |
| Apr 29, 2026 | Patel Sanj K | CHAIRMAN & CEO | S | 22,544 | $54.0100 | $1.22M |
| Apr 29, 2026 | Patel Sanj K | CHAIRMAN & CEO | M | 22,544 | $30.9300 | $697.28K |
| Apr 28, 2026 | Quart Barry D | Director | M | 13,099 | $0.0000 | $0.00 |