| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 7, 2026 | Horn Kinney | CHIEF BUSINESS OFFICER | M | 1,092 | $0.0000 | $0.00 |
| Jul 7, 2026 | Horn Kinney | CHIEF BUSINESS OFFICER | S | 1,092 | $25.0000 | $27.30K |
| Jul 7, 2026 | Horn Kinney | CHIEF BUSINESS OFFICER | M | 1,092 | $12.9200 | $14.11K |
| Jul 7, 2026 | Barchas Isaac | Director | S | 16,906 | $24.2000 | $409.13K |
| Jul 6, 2026 | Barchas Isaac | Director | S | 83,094 | $24.1100 | $2.00M |
| Jul 2, 2026 | Lechleider Robert | Chief Medical Officer | M | 55,000 | $0.0000 | $0.00 |
| Jul 2, 2026 | Lechleider Robert | Chief Medical Officer | S | 16,072 | $23.4400 | $376.73K |
| Jul 2, 2026 | Lechleider Robert | Chief Medical Officer | S | 16,214 | $22.7600 | $369.03K |
| Jul 2, 2026 | Lechleider Robert | Chief Medical Officer | S | 22,714 | $21.9500 | $498.57K |
| Jul 2, 2026 | Lechleider Robert | Chief Medical Officer | M | 55,000 | $8.7300 | $480.15K |
| Jul 2, 2026 | Barchas Isaac | Director | S | 24,335 | $23.3300 | $567.74K |
| Jul 2, 2026 | Barchas Isaac | Director | S | 75,665 | $22.3500 | $1.69M |
| Jun 30, 2026 | Barchas Isaac | Director | S | 101,050 | $21.1200 | $2.13M |
| Jun 25, 2026 | Lechleider Robert | Chief Medical Officer | M | 55,000 | $0.0000 | $0.00 |
| Jun 25, 2026 | Lechleider Robert | Chief Medical Officer | S | 14,420 | $20.6600 | $297.92K |
| Jun 25, 2026 | Lechleider Robert | Chief Medical Officer | S | 40,580 | $19.5600 | $793.74K |
| Jun 25, 2026 | Lechleider Robert | Chief Medical Officer | M | 55,000 | $8.7300 | $480.15K |
| Jun 15, 2026 | Rosett Max | Chief Financial Officer | M | 60,000 | $0.0000 | $0.00 |
| Jun 15, 2026 | Rosett Max | Chief Financial Officer | S | 60,000 | $18.2300 | $1.09M |
| Jun 15, 2026 | Rosett Max | Chief Financial Officer | M | 60,000 | $1.0500 | $63.00K |
| Jun 10, 2026 | Barchas Isaac | Director | A | 9,897 | $0.0000 | $0.00 |
| Jun 10, 2026 | SCHAFER CAROL | Director | A | 9,897 | $0.0000 | $0.00 |
| Jun 10, 2026 | Boylan James P | Director | A | 9,897 | $0.0000 | $0.00 |
| Jun 10, 2026 | BIENAIME JEAN JACQUES | Director | A | 9,897 | $0.0000 | $0.00 |
| Jun 10, 2026 | WAGENHEIM PHILIP | Director | A | 9,897 | $0.0000 | $0.00 |
| Jun 10, 2026 | SWAIN SANDRA M | Director | A | 9,897 | $0.0000 | $0.00 |
| Jun 5, 2026 | BIENAIME JEAN JACQUES | Director | P | 1,000 | $19.2700 | $19.27K |
| Jun 5, 2026 | BIENAIME JEAN JACQUES | Director | P | 3,500 | $19.4600 | $68.11K |
| Jun 5, 2026 | BIENAIME JEAN JACQUES | Director | P | 6,000 | $19.4800 | $116.88K |
| Jun 5, 2026 | BIENAIME JEAN JACQUES | Director | S | 10,000 | $19.4100 | $194.10K |
| Jun 5, 2026 | BIENAIME JEAN JACQUES | Director | S | 500 | $19.4400 | $9.72K |
| May 15, 2026 | BIENAIME JEAN JACQUES | Director | P | 5,000 | $20.7000 | $103.50K |
| Apr 2, 2026 | Higgins Jack | Chief Scientific Officer | S | 9,438 | $21.6400 | $204.24K |
| Apr 2, 2026 | Rosett Max | Chief Financial Officer | M | 39,713 | $0.0000 | $0.00 |
| Apr 2, 2026 | Rosett Max | Chief Financial Officer | M | 31,848 | $0.0000 | $0.00 |
| Apr 2, 2026 | Rosett Max | Chief Financial Officer | S | 1,344 | $22.4800 | $30.21K |
| Apr 2, 2026 | Rosett Max | Chief Financial Officer | S | 63,656 | $21.9100 | $1.39M |
| Apr 2, 2026 | Rosett Max | Chief Financial Officer | M | 39,713 | $1.3500 | $53.61K |
| Apr 2, 2026 | Rosett Max | Chief Financial Officer | M | 31,848 | $1.0500 | $33.44K |
| Mar 30, 2026 | Higgins Jack | Chief Scientific Officer | G | 6,291 | $0.0000 | $0.00 |
| Mar 27, 2026 | SIEGALL CLAY B | President and CEO | P | 25,450 | $19.6700 | $500.60K |
| Mar 23, 2026 | WAGENHEIM PHILIP | Director | S | 28,200 | $20.6500 | $582.33K |
| Mar 20, 2026 | WAGENHEIM PHILIP | Director | S | 36,800 | $20.4700 | $753.30K |
| Mar 11, 2026 | BIENAIME JEAN JACQUES | Director | P | 1,000 | $21.5500 | $21.55K |
| Mar 10, 2026 | BIENAIME JEAN JACQUES | Director | P | 1,000 | $22.1200 | $22.12K |
| Dec 30, 2025 | SIEGALL CLAY B | President and CEO | P | 4,729 | $21.1500 | $100.02K |
| Dec 22, 2025 | Barchas Isaac | Director | S | 11,251 | $22.3400 | $251.35K |
| Dec 22, 2025 | Barchas Isaac | Director | S | 371,949 | $21.7200 | $8.08M |
| Dec 19, 2025 | SIEGALL CLAY B | President and CEO | G | 200,000 | $0.0000 | $0.00 |
| Dec 19, 2025 | SIEGALL CLAY B | President and CEO | P | 7,278 | $20.4800 | $149.05K |