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Institutional Holders · 13F

First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.

Ownership

Institutions100.0%
Insiders0.7%
Institutions Count144
Institutions 100.0%Insiders 0.7%Float (Other) 0.0%
13F Filers (top 25)25Quarter 2026-03-31
Top-25 Reported Value$1.33BSum of shown holders' market value
Net Position Change10 adds · 10 trimsLargest movers this quarter

Top Holders by Value

25 shown
FilerSharesMarket ValueΔ SharesChange
RTW INVESTMENTS, LPCIK 0001493215
4,869,798$146.82M–no_change
FMR LLCCIK 0000315066
4,829,154$145.60M+289,929↑ INC
WELLINGTON MANAGEMENT GROUP LLPCIK 0000902219
4,706,168$141.89M+12,525↑ INC
PRIMECAP MANAGEMENT CO/CA/CIK 0000763212
3,693,241$111.35M-268,639↓ DEC
Bellevue Group AGCIK 0001674546
2,796,803$84.32M–no_change
Vestal Point Capital, LPCIK 0001974915
2,766,868$83.42M+2,181,868↑ INC
TANG CAPITAL MANAGEMENT LLCCIK 0001232621
2,649,368$79.88M+20,830↑ INC
Caption Management, LLCCIK 0001706766
1,934,286$58.32M+1,814,902↑ INC
Deep Track Capital, LPCIK 0001856083
1,931,884$58.25M-72,094↓ DEC
BVF INC/ILCIK 0001056807
1,294,463$39.03M-194,512↓ DEC
CAMDEN ASSET MANAGEMENT L P /CACIK 0000903944
42,728,000$38.32M+6,493,000↑ INC
MILLENNIUM MANAGEMENT LLCCIK 0001273087
1,237,403$37.31M+325,806↑ INC
ARMISTICE CAPITAL, LLCCIK 0001601086
1,188,000$35.82M+90,000↑ INC
Point72 Asset Management, L.P.CIK 0001603466
1,102,271$33.23M+598,120↑ INC
Fiera Capital CorpCIK 0001505817
1,080,099$32.56M+35,268↑ INC
TWO SIGMA INVESTMENTS, LPCIK 0001179392
1,021,265$30.79M+661,972↑ INC
DEERFIELD MANAGEMENT COMPANY, L.P.CIK 0001009258
30,000,000$27.03M–no_change
BAKER BROS. ADVISORS LPCIK 0001263508
734,397$22.14M-1,588,259↓ DEC
Trails Edge Capital Partners, LPCIK 0002077247
682,597$20.58M–no_change
BlackRock, Inc.CIK 0002012383
656,309$19.79M+327,210↑ INC
Hudson Bay Capital Management LPCIK 0001393825
633,174$19.09M+249,616↑ INC
FRANKLIN RESOURCES INCCIK 0000038777
20,000,000$18.04M–no_change
JANE STREET GROUP, LLCCIK 0001595888
596,268$17.98M+473,628↑ INC
PRINCIPAL FINANCIAL GROUP INCCIK 0001126328
519,130$15.65M-139,306↓ DEC
Frazier Life Sciences Management, L.P.CIK 0001892134
484,782$14.62M+100,000↑ INC

Top Adds (Buyers)

FilerΔ SharesValue
CAMDEN ASSET MANAGEMENT L P /CA↑ INC
+6,493,000$38.32M
Vestal Point Capital, LP↑ INC
+2,181,868$83.42M
Caption Management, LLC↑ INC
+1,814,902$58.32M
T. Rowe Price Investment Management, Inc.↑ INC
+1,017,972$57.03K
TWO SIGMA INVESTMENTS, LP↑ INC
+661,972$30.79M
Point72 Asset Management, L.P.↑ INC
+598,120$33.23M
JANE STREET GROUP, LLC↑ INC
+473,628$17.98M
BlackRock, Inc.↑ INC
+327,210$19.79M
MILLENNIUM MANAGEMENT LLC↑ INC
+325,806$37.31M
FMR LLC↑ INC
+289,929$145.60M

Top Trims (Sellers)

FilerΔ SharesValue
Ares Systematic Credit Ltd↓ DEC
-2,300,000$1.95M
BAKER BROS. ADVISORS LP↓ DEC
-1,588,259$22.14M
STEMPOINT CAPITAL LP↓ DEC
-275,808$1.92M
PRIMECAP MANAGEMENT CO/CA/↓ DEC
-268,639$111.35M
BVF INC/IL↓ DEC
-194,512$39.03M
TD ASSET MANAGEMENT INC↓ DEC
-156,936$4.10M
PRINCIPAL FINANCIAL GROUP INC↓ DEC
-139,306$15.65M
Trexquant Investment LP↓ DEC
-79,895$623.65K
BARCLAYS PLC↓ DEC
-72,344$931.91K
Deep Track Capital, LP↓ DEC
-72,094$58.25M