First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
EQT Fund Management S.a r.l.CIK 0001834239 | 4,929,633 | $113.33M | – | no_change |
Pivotal bioVenture Partners Investment Advisor LLCCIK 0001844645 | 1,926,943 | $44.30M | – | no_change |
Andera PartnersCIK 0001757283 | 1,897,362 | $43.62M | – | no_change |
RTW INVESTMENTS, LPCIK 0001493215 | 1,502,235 | $34.54M | +218,564 | ↑ INC |
MPM BioImpact LLCCIK 0001687078 | 1,455,863 | $33.47M | +1,342,841 | ↑ INC |
Nan Fung Group Holdings LtdCIK 0001782539 | 1,441,032 | $33.13M | – | no_change |
JPMORGAN CHASE & COCIK 0000019617 | 1,459,420 | $32.11M | +150,519 | ↑ INC |
SymBiosis Capital Partners, LLCCIK 0002006045 | 1,280,778 | $29.45M | – | no_change |
EVENTIDE ASSET MANAGEMENT, LLCCIK 0001442891 | 1,209,129 | $27.80M | +247,604 | ↑ INC |
MARSHALL WACE, LLPCIK 0001318757 | 879,728 | $20.22M | -108,472 | ↓ DEC |
BAKER BROS. ADVISORS LPCIK 0001263508 | 847,390 | $19.48M | +847,390 | NEW |
Alyeska Investment Group, L.P.CIK 0001453072 | 726,362 | $16.70M | +726,362 | NEW |
BlackRock, Inc.CIK 0002012383 | 673,571 | $15.49M | +531,131 | ↑ INC |
SECTORAL ASSET MANAGEMENT INCCIK 0001274413 | 589,005 | $13.54M | – | no_change |
Verition Fund Management LLCCIK 0001454027 | 549,991 | $12.64M | -15,223 | ↓ DEC |
AMERICAN CENTURY COMPANIES INCCIK 0000748054 | 492,938 | $11.33M | +75,483 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 455,051 | $10.46M | +455,051 | NEW |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 448,350 | $10.31M | +448,350 | NEW |
Velan Capital Investment Management LPCIK 0001848809 | 446,255 | $10.26M | -60,499 | ↓ DEC |
Freestone Grove Partners LPCIK 0002007591 | 337,291 | $7.75M | +337,291 | NEW |
GREAT POINT PARTNERS LLCCIK 0001281446 | 325,000 | $7.47M | – | no_change |
FEDERATED HERMES, INC.CIK 0001056288 | 325,000 | $7.47M | – | no_change |
UBS Group AGCIK 0001610520 | 298,375 | $6.86M | +294,961 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 248,611 | $5.72M | +138,830 | ↑ INC |
E Fund Management Co., Ltd.CIK 0001842296 | 243,700 | $5.60M | +243,700 | NEW |
| Filer | Δ Shares | Value |
|---|---|---|
MPM BioImpact LLC↑ INC | +1,342,841 | $33.47M |
BAKER BROS. ADVISORS LPNEW | +847,390 | $19.48M |
Alyeska Investment Group, L.P.NEW | +726,362 | $16.70M |
BlackRock, Inc.↑ INC | +531,131 | $15.49M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +455,051 | $10.46M |
PERCEPTIVE ADVISORS LLCNEW | +448,350 | $10.31M |
Freestone Grove Partners LPNEW | +337,291 | $7.75M |
PRICE T ROWE ASSOCIATES INC /MD/↑ INC | +336,900 | $25.73K |
UBS Group AG↑ INC | +294,961 | $6.86M |
EVENTIDE ASSET MANAGEMENT, LLC↑ INC | +247,604 | $27.80M |
| Filer | Δ Shares | Value |
|---|---|---|
Octagon Capital Advisors LP↓ DEC | -356,528 | $3.30M |
MARSHALL WACE, LLP↓ DEC | -108,472 | $20.22M |
SPHERA FUNDS MANAGEMENT LTD.↓ DEC | -87,913 | $1.80M |
Velan Capital Investment Management LP↓ DEC | -60,499 | $10.26M |
NEXTBio Capital Management LP↓ DEC | -44,223 | $4.23M |
Verition Fund Management LLC↓ DEC | -15,223 | $12.64M |
AMERIPRISE FINANCIAL INC↓ DEC | -13,126 | $2.10M |
XTX Topco Ltd↓ DEC | -6,738 | $276.80K |
TD ASSET MANAGEMENT INC↓ DEC | -4,424 | $924.43K |
Monashee Investment Management LLC↓ DEC | -3,899 | $4.12M |