| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 25, 2026 | Liu Brian Guan-Chyun | Director | P | 371,085 | $66.8700 | $24.81M |
| Jun 24, 2026 | POST LEONARD E | Director | M | 5,000 | $0.0000 | $0.00 |
| Jun 24, 2026 | POST LEONARD E | Director | S | 5,000 | $70.0000 | $350.00K |
| Jun 24, 2026 | POST LEONARD E | Director | M | 5,000 | $0.6000 | $3.00K |
| Jun 22, 2026 | POST LEONARD E | Director | M | 5,000 | $0.0000 | $0.00 |
| Jun 22, 2026 | POST LEONARD E | Director | S | 5,000 | $65.0000 | $325.00K |
| Jun 22, 2026 | POST LEONARD E | Director | M | 5,000 | $0.6000 | $3.00K |
| Jun 15, 2026 | Mulay James | Director | M | 1,310 | $0.0000 | $0.00 |
| Jun 15, 2026 | Mulay James | Director | M | 654 | $0.0000 | $0.00 |
| Jun 15, 2026 | Mulay James | Director | S | 1,310 | $60.1200 | $78.76K |
| Jun 15, 2026 | Mulay James | Director | M | 1,310 | $12.5900 | $16.49K |
| Jun 15, 2026 | Mulay James | Director | S | 654 | $60.1200 | $39.32K |
| Jun 15, 2026 | Mulay James | Director | M | 654 | $3.7200 | $2.43K |
| Jun 4, 2026 | Graf Susan E | Director | A | 9,354 | $0.0000 | $0.00 |
| Jun 4, 2026 | POST LEONARD E | Director | A | 9,354 | $0.0000 | $0.00 |
| Jun 4, 2026 | POST LEONARD E | Director | M | 1,000 | $0.0000 | $0.00 |
| Jun 4, 2026 | POST LEONARD E | Director | S | 1,000 | $54.5000 | $54.50K |
| Jun 4, 2026 | POST LEONARD E | Director | M | 1,000 | $0.6000 | $600.00 |
| Jun 4, 2026 | Rossi Christina | Director | A | 9,354 | $0.0000 | $0.00 |
| Jun 4, 2026 | Mulay James | Director | A | 9,354 | $0.0000 | $0.00 |
| Jun 4, 2026 | Tong Victor Edward Jr | Director | A | 9,354 | $0.0000 | $0.00 |
| Jun 4, 2026 | Liu Brian Guan-Chyun | Director | A | 9,354 | $0.0000 | $0.00 |
| Apr 17, 2026 | Mulay James | Director | M | 15,600 | $0.0000 | $0.00 |
| Apr 17, 2026 | Mulay James | Director | S | 15,600 | $73.0100 | $1.14M |
| Apr 17, 2026 | Mulay James | Director | M | 15,600 | $36.6300 | $571.43K |
| Apr 15, 2026 | Kuan Arthur | Chief Executive Officer | A | 271,600 | $0.0000 | $0.00 |
| Apr 15, 2026 | DETORE JAMES M. | Chief Financial Officer | A | 90,574 | $0.0000 | $0.00 |
| Apr 15, 2026 | Patterson Joshua F. | See Remarks | A | 45,266 | $0.0000 | $0.00 |
| Apr 15, 2026 | Bellete Ambaw | President and COO | A | 107,508 | $0.0000 | $0.00 |
| Apr 15, 2026 | Kasturi Vijay | Chief Medical Officer | A | 79,216 | $0.0000 | $0.00 |
| Mar 16, 2026 | Mulay James | Director | M | 1,310 | $0.0000 | $0.00 |
| Mar 16, 2026 | Mulay James | Director | M | 654 | $0.0000 | $0.00 |
| Mar 16, 2026 | Mulay James | Director | S | 1,310 | $63.5000 | $83.19K |
| Mar 16, 2026 | Mulay James | Director | M | 1,310 | $12.5900 | $16.49K |
| Mar 16, 2026 | Mulay James | Director | S | 654 | $63.5000 | $41.53K |
| Mar 16, 2026 | Mulay James | Director | M | 654 | $3.7200 | $2.43K |
| Mar 12, 2026 | Kuan Arthur | Chief Executive Officer | M | 64,612 | $0.0000 | $0.00 |
| Mar 12, 2026 | Kuan Arthur | Chief Executive Officer | F | 1,847 | $60.1500 | $111.10K |
| Mar 12, 2026 | Kuan Arthur | Chief Executive Officer | M | 64,612 | $1.7200 | $111.13K |
| Mar 4, 2026 | Kuan Arthur | Chief Executive Officer | M | 102,871 | $0.0000 | $0.00 |
| Mar 4, 2026 | Kuan Arthur | Chief Executive Officer | F | 2,871 | $61.6100 | $176.88K |
| Mar 4, 2026 | Kuan Arthur | Chief Executive Officer | M | 102,871 | $1.7200 | $176.94K |
| Jan 9, 2026 | Mulay James | Director | M | 10,491 | $0.0000 | $0.00 |
| Jan 9, 2026 | Mulay James | Director | M | 654 | $0.0000 | $0.00 |
| Jan 9, 2026 | Mulay James | Director | S | 10,491 | $52.9900 | $555.92K |
| Jan 9, 2026 | Mulay James | Director | M | 10,491 | $12.5900 | $132.08K |
| Jan 9, 2026 | Mulay James | Director | S | 654 | $44.1600 | $28.88K |
| Jan 9, 2026 | Mulay James | Director | M | 654 | $3.7200 | $2.43K |
| Nov 24, 2025 | Rossi Christina | Director | A | 20,889 | $0.0000 | $0.00 |
| Nov 17, 2025 | POST LEONARD E | Director | M | 1,000 | $0.0000 | $0.00 |