| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 6, 2026 | Michaelson Jennifer | Chief Scientific Officer | M | 4,000 | $0.0000 | $0.00 |
| Jul 6, 2026 | Michaelson Jennifer | Chief Scientific Officer | S | 8,000 | $17.8200 | $142.56K |
| Jul 6, 2026 | Michaelson Jennifer | Chief Scientific Officer | M | 4,000 | $4.3000 | $17.20K |
| Jun 30, 2026 | Fenton Mary Kay | Chief Financial Officer | A | 1,541 | $8.6000 | $13.25K |
| Jun 30, 2026 | SUMER JACQUELYN L | Chief Legal Officer | A | 2,470 | $8.6000 | $21.24K |
| Jun 16, 2026 | Doyle Mittie | Director | A | 21,781 | $0.0000 | $0.00 |
| Jun 16, 2026 | Thistle Mary | Director | A | 25,319 | $0.0000 | $0.00 |
| Jun 16, 2026 | Allen Andrew R | Director | A | 21,781 | $0.0000 | $0.00 |
| Jun 16, 2026 | Webster Stephen W | Director | A | 25,319 | $0.0000 | $0.00 |
| Jun 16, 2026 | Meek David D. | Director | A | 25,319 | $0.0000 | $0.00 |
| Jun 16, 2026 | Rosenberg Anthony | Director | A | 25,319 | $0.0000 | $0.00 |
| May 5, 2026 | Michaelson Jennifer | Chief Scientific Officer | M | 4,000 | $0.0000 | $0.00 |
| May 5, 2026 | Michaelson Jennifer | Chief Scientific Officer | S | 200 | $15.5800 | $3.12K |
| May 5, 2026 | Michaelson Jennifer | Chief Scientific Officer | S | 7,800 | $14.6000 | $113.88K |
| May 5, 2026 | Michaelson Jennifer | Chief Scientific Officer | M | 4,000 | $4.3000 | $17.20K |
| Mar 5, 2026 | Michaelson Jennifer | Chief Scientific Officer | M | 4,000 | $0.0000 | $0.00 |
| Mar 5, 2026 | Michaelson Jennifer | Chief Scientific Officer | S | 8,000 | $15.6800 | $125.44K |
| Mar 5, 2026 | Michaelson Jennifer | Chief Scientific Officer | M | 4,000 | $4.3000 | $17.20K |
| Feb 25, 2026 | Michaelson Jennifer | Chief Scientific Officer | S | 1,780 | $14.1400 | $25.17K |
| Feb 24, 2026 | Jones Jeffrey Alan | Chief Medical Officer | S | 4,582 | $14.4700 | $66.30K |
| Feb 24, 2026 | SUMER JACQUELYN L | Chief Legal Officer | S | 3,601 | $14.4700 | $52.11K |
| Feb 24, 2026 | Michaelson Jennifer | Chief Scientific Officer | S | 3,601 | $14.4700 | $52.11K |
| Feb 24, 2026 | AHMED NADIM | President and CEO | S | 13,515 | $14.4700 | $195.56K |
| Feb 23, 2026 | Michaelson Jennifer | Chief Scientific Officer | S | 1,752 | $13.9900 | $24.51K |
| Feb 20, 2026 | Fenton Mary Kay | Chief Financial Officer | S | 4,398 | $13.6200 | $59.90K |
| Feb 20, 2026 | SUMER JACQUELYN L | Chief Legal Officer | S | 3,742 | $13.6200 | $50.97K |
| Feb 20, 2026 | AHMED NADIM | President and CEO | S | 16,381 | $13.6200 | $223.11K |
| Feb 20, 2026 | Michaelson Jennifer | Chief Scientific Officer | M | 8,000 | $0.0000 | $0.00 |
| Feb 20, 2026 | Michaelson Jennifer | Chief Scientific Officer | S | 8,000 | $14.3000 | $114.40K |
| Feb 20, 2026 | Michaelson Jennifer | Chief Scientific Officer | M | 8,000 | $4.3000 | $34.40K |
| Feb 20, 2026 | Michaelson Jennifer | Chief Scientific Officer | S | 3,742 | $13.6200 | $50.97K |
| Feb 20, 2026 | Jones Jeffrey Alan | Chief Medical Officer | S | 4,982 | $13.6200 | $67.85K |
| Feb 18, 2026 | Michaelson Jennifer | Chief Scientific Officer | A | 115,000 | $0.0000 | $0.00 |
| Feb 18, 2026 | Michaelson Jennifer | Chief Scientific Officer | A | 57,500 | $0.0000 | $0.00 |
| Feb 18, 2026 | Fenton Mary Kay | Chief Financial Officer | A | 137,500 | $0.0000 | $0.00 |
| Feb 18, 2026 | Fenton Mary Kay | Chief Financial Officer | A | 68,750 | $0.0000 | $0.00 |
| Feb 18, 2026 | SUMER JACQUELYN L | Chief Legal Officer | A | 230,000 | $0.0000 | $0.00 |
| Feb 18, 2026 | Savill Corrine | Chief Business Officer | A | 175,000 | $0.0000 | $0.00 |
| Feb 18, 2026 | AHMED NADIM | President and CEO | A | 828,000 | $0.0000 | $0.00 |
| Feb 18, 2026 | Jones Jeffrey Alan | Chief Medical Officer | A | 300,000 | $0.0000 | $0.00 |
| Feb 12, 2026 | Michaelson Jennifer | Chief Scientific Officer | S | 416 | $12.0300 | $5.00K |
| Jan 22, 2026 | Michaelson Jennifer | Chief Scientific Officer | S | 4,000 | $12.3000 | $49.20K |
| Dec 31, 2025 | Fenton Mary Kay | Chief Financial Officer | A | 27 | $6.4900 | $175.00 |
| Dec 23, 2025 | AHMED NADIM | President and CEO | S | 9,922 | $10.0100 | $99.32K |
| Dec 19, 2025 | Michaelson Jennifer | Chief Scientific Officer | S | 1,345 | $10.0100 | $13.46K |
| Dec 18, 2025 | Michaelson Jennifer | Chief Scientific Officer | S | 2,898 | $9.6700 | $28.02K |
| Dec 18, 2025 | Jones Jeffrey Alan | Chief Medical Officer | S | 4,632 | $9.6700 | $44.79K |
| Dec 18, 2025 | SUMER JACQUELYN L | Chief Legal Officer | S | 3,480 | $9.6700 | $33.65K |
| Dec 15, 2025 | Michaelson Jennifer | Chief Scientific Officer | S | 995 | $11.9000 | $11.84K |
| Dec 12, 2025 | Michaelson Jennifer | Chief Scientific Officer | S | 2,148 | $12.3800 | $26.59K |