第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
BVF INC/ILCIK 0001056807 | 2,590,303 | $81.26M | – | no_change |
MORGAN STANLEYCIK 0000895421 | 1,702,157 | $53.40M | -12,511 | ↓ DEC |
FMR LLCCIK 0000315066 | 1,302,974 | $40.87M | +141,085 | ↑ INC |
BlackRock, Inc.CIK 0002012383 | 646,914 | $20.29M | +35,399 | ↑ INC |
Woodline Partners LPCIK 0001784547 | 640,001 | $20.08M | +377,068 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 549,796 | $17.25M | +549,796 | NEW |
Opaleye Management Inc.CIK 0001595855 | 300,000 | $9.41M | +7,410 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 229,766 | $7.21M | +8,200 | ↑ INC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 204,920 | $6.43M | +190,866 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 193,148 | $6.06M | +18,240 | ↑ INC |
DIMENSIONAL FUND ADVISORS LPCIK 0000354204 | 133,360 | $4.18M | +90,025 | ↑ INC |
CITADEL ADVISORS LLCCIK 0001423053 | 110,238 | $3.46M | +102,657 | ↑ INC |
NORTHERN TRUST CORPCIK 0000073124 | 93,490 | $2.93M | +3,087 | ↑ INC |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 85,797 | $2.69M | +85,797 | NEW |
Bank of New York Mellon CorpCIK 0001390777 | 74,984 | $2.35M | +6,600 | ↑ INC |
UBS Group AGCIK 0001610520 | 72,533 | $2.28M | +46,486 | ↑ INC |
Stonepine Capital Management, LLCCIK 0001440771 | 69,500 | $2.18M | -45,500 | ↓ DEC |
Simcoe Capital LLCCIK 0002109203 | 68,053 | $2.13M | +68,053 | NEW |
VANGUARD FIDUCIARY TRUST COCIK 0000933478 | 66,664 | $2.09M | +66,664 | NEW |
PANAGORA ASSET MANAGEMENT INCCIK 0000883677 | 58,662 | $1.84M | +37,433 | ↑ INC |
HighVista Strategies LLCCIK 0001335325 | 46,814 | $1.47M | -66,103 | ↓ DEC |
CM Management, LLCCIK 0001841857 | 40,000 | $1.25M | – | no_change |
RBF Capital, LLCCIK 0001134621 | 30,000 | $941.10K | – | no_change |
STATE OF WISCONSIN INVESTMENT BOARDCIK 0000854157 | 28,894 | $906.40K | +15,323 | ↑ INC |
Quadrature Capital LtdCIK 0001651424 | 28,495 | $893.89K | +28,495 | NEW |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +549,796 | $17.25M |
Woodline Partners LP↑ INC | +377,068 | $20.08M |
GW&K Investment Management, LLCNEW | +232,141 | $7.28K |
MILLENNIUM MANAGEMENT LLC↑ INC | +190,866 | $6.43M |
FMR LLC↑ INC | +141,085 | $40.87M |
CITADEL ADVISORS LLC↑ INC | +102,657 | $3.46M |
DIMENSIONAL FUND ADVISORS LP↑ INC | +90,025 | $4.18M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +85,797 | $2.69M |
Simcoe Capital LLCNEW | +68,053 | $2.13M |
TLS Advisors LLC↑ INC | +66,944 | $3.60K |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
HighVista Strategies LLC↓ DEC | -66,103 | $1.47M |
Stonepine Capital Management, LLC↓ DEC | -45,500 | $2.18M |
LOS ANGELES CAPITAL MANAGEMENT LLC↓ DEC | -19,142 | $5.96K |
BARCLAYS PLC↓ DEC | -12,857 | $61.64K |
MORGAN STANLEY↓ DEC | -12,511 | $53.40M |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC↓ DEC | -2,224 | $851.73K |
JANE STREET GROUP, LLC↓ DEC | -2,144 | $791.12K |
PRICE T ROWE ASSOCIATES INC /MD/↓ DEC | -1,975 | $214.00 |
BANK OF AMERICA CORP /DE/↓ DEC | -924 | $345.63K |
ROYAL BANK OF CANADA↓ DEC | -241 | $31.00K |