第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
FMR LLCCIK 0000315066 | 15,379,377 | $300.82M | +994,921 | ↑ INC |
BlackRock, Inc.CIK 0002012383 | 7,831,475 | $153.18M | +1,399,552 | ↑ INC |
Bellevue Group AGCIK 0001674546 | 6,726,144 | $131.56M | +2,367,617 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 4,672,885 | $91.40M | +1,206,325 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 4,167,201 | $81.51M | +4,167,201 | NEW |
Fairmount Funds Management LLCCIK 0001802528 | 3,914,458 | $76.57M | – | no_change |
Venrock Adviser, LLCCIK 0001615982 | 3,882,709 | $75.95M | – | no_change |
Paradigm Biocapital Advisors LPCIK 0001855655 | 3,148,893 | $61.59M | +1,705,791 | ↑ INC |
WELLINGTON MANAGEMENT GROUP LLPCIK 0000902219 | 3,078,554 | $60.22M | +1,107,143 | ↑ INC |
CITADEL ADVISORS LLCCIK 0001423053 | 2,382,934 | $46.61M | +1,681,840 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 2,333,213 | $45.65M | +341,039 | ↑ INC |
BALYASNY ASSET MANAGEMENT L.P.CIK 0001218710 | 2,315,957 | $45.30M | +1,812,089 | ↑ INC |
ALLIANCEBERNSTEIN L.P.CIK 0001109448 | 1,392,072 | $43.32M | -22,109 | ↓ DEC |
Novo Holdings A/SCIK 0001388325 | 2,000,000 | $39.12M | -380,000 | ↓ DEC |
BAKER BROS. ADVISORS LPCIK 0001263508 | 1,971,678 | $38.57M | – | no_change |
TANG CAPITAL MANAGEMENT LLCCIK 0001232621 | 1,792,626 | $35.06M | – | no_change |
Fisher Asset Management, LLCCIK 0000850529 | 1,768,295 | $34.59M | -11,989 | ↓ DEC |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 1,641,477 | $32.11M | +1,641,477 | NEW |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 1,591,945 | $31.14M | +327,898 | ↑ INC |
Avoro Capital Advisors LLCCIK 0001633313 | 1,500,000 | $29.34M | – | no_change |
Deep Track Capital, LPCIK 0001856083 | 1,393,944 | $27.27M | -1,130,889 | ↓ DEC |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 1,170,829 | $22.90M | -1,871,874 | ↓ DEC |
BANK OF AMERICA CORP /DE/CIK 0000070858 | 1,163,615 | $22.76M | +173,498 | ↑ INC |
DEUTSCHE BANK AG\CIK 0000948046 | 1,032,316 | $20.19M | +552,558 | ↑ INC |
JPMORGAN CHASE & COCIK 0000019617 | 1,059,864 | $19.64M | +49,604 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +4,167,201 | $81.51M |
Bellevue Group AG↑ INC | +2,367,617 | $131.56M |
BALYASNY ASSET MANAGEMENT L.P.↑ INC | +1,812,089 | $45.30M |
Paradigm Biocapital Advisors LP↑ INC | +1,705,791 | $61.59M |
CITADEL ADVISORS LLC↑ INC | +1,681,840 | $46.61M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +1,641,477 | $32.11M |
BlackRock, Inc.↑ INC | +1,399,552 | $153.18M |
STATE STREET CORP↑ INC | +1,206,325 | $91.40M |
WELLINGTON MANAGEMENT GROUP LLP↑ INC | +1,107,143 | $60.22M |
FMR LLC↑ INC | +994,921 | $300.82M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
PERCEPTIVE ADVISORS LLC↓ DEC | -1,871,874 | $22.90M |
Deep Track Capital, LP↓ DEC | -1,130,889 | $27.27M |
JENNISON ASSOCIATES LLC↓ DEC | -1,126,021 | $548.83K |
MARSHALL WACE, LLP↓ DEC | -1,106,152 | $5.27M |
Eversept Partners, LP↓ DEC | -1,068,966 | $13.95M |
MORGAN STANLEY↓ DEC | -868,063 | $17.02M |
Vivo Capital, LLC↓ DEC | -816,288 | $3.25M |
Pictet Asset Management Holding SA↓ DEC | -608,736 | $6.14M |
LOOMIS SAYLES & CO L P↓ DEC | -553,418 | $18.15M |
Woodline Partners LP↓ DEC | -415,000 | $13.71M |