第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
GOLDMAN SACHS GROUP INCCIK 0000886982 | 22,369,645 | $99.99M | +8,676,906 | ↑ INC |
Avoro Capital Advisors LLCCIK 0001633313 | 21,700,000 | $97.00M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 18,365,608 | $82.09M | -277,521 | ↓ DEC |
Vestal Point Capital, LPCIK 0001974915 | 18,000,000 | $80.46M | +4,250,000 | ↑ INC |
MORGAN STANLEYCIK 0000895421 | 17,965,371 | $80.31M | -113,147 | ↓ DEC |
FMR LLCCIK 0000315066 | 14,321,255 | $64.02M | +792,889 | ↑ INC |
RTW INVESTMENTS, LPCIK 0001493215 | 13,680,248 | $61.15M | -2,718,049 | ↓ DEC |
STATE STREET CORPCIK 0000093751 | 11,209,078 | $50.10M | +418,994 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 10,231,502 | $45.73M | +10,231,502 | NEW |
Octagon Capital Advisors LPCIK 0001839435 | 8,859,911 | $39.60M | – | no_change |
Siren, L.L.C.CIK 0002005245 | 8,829,913 | $39.47M | -1,300,000 | ↓ DEC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 5,531,955 | $24.73M | +144,929 | ↑ INC |
GordonMD Global Investments LPCIK 0002039349 | 737,550 | $22.22M | -593,351 | ↓ DEC |
EverSource Wealth Advisors, LLCCIK 0001710537 | 127,753 | $18.68M | +127,662 | ↑ INC |
BAKER BROS. ADVISORS LPCIK 0001263508 | 4,004,756 | $17.90M | – | no_change |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 3,281,820 | $14.67M | +102,957 | ↑ INC |
Casdin Capital, LLCCIK 0001534261 | 3,250,000 | $14.53M | +1,750,000 | ↑ INC |
ADAR1 Capital Management, LLCCIK 0001940272 | 2,979,429 | $13.32M | +483,620 | ↑ INC |
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUNDCIK 0001535845 | 2,883,301 | $12.89M | -838,699 | ↓ DEC |
DEERFIELD MANAGEMENT COMPANY, L.P.CIK 0001009258 | 2,722,165 | $12.17M | – | no_change |
BARCLAYS PLCCIK 0000312069 | 2,812,010 | $11.44M | -2,726,991 | ↓ DEC |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 2,022,498 | $9.04M | +2,022,498 | NEW |
RICE HALL JAMES & ASSOCIATES, LLCCIK 0001230765 | 1,944,671 | $8.69M | +674,026 | ↑ INC |
NORTHERN TRUST CORPCIK 0000073124 | 1,814,318 | $8.11M | +576,331 | ↑ INC |
CHARLES SCHWAB INVESTMENT MANAGEMENT INCCIK 0000884546 | 1,808,599 | $8.08M | -94,379 | ↓ DEC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +10,231,502 | $45.73M |
GOLDMAN SACHS GROUP INC↑ INC | +8,676,906 | $99.99M |
Vestal Point Capital, LP↑ INC | +4,250,000 | $80.46M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +2,022,498 | $9.04M |
Casdin Capital, LLC↑ INC | +1,750,000 | $14.53M |
VANGUARD FIDUCIARY TRUST CONEW | +1,530,461 | $6.84M |
SG Americas Securities, LLC↑ INC | +1,395,268 | $9.73K |
FMR LLC↑ INC | +792,889 | $64.02M |
RICE HALL JAMES & ASSOCIATES, LLC↑ INC | +674,026 | $8.69M |
NORTHERN TRUST CORP↑ INC | +576,331 | $8.11M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
Point72 Asset Management, L.P.↓ DEC | -3,406,826 | $2.06M |
BARCLAYS PLC↓ DEC | -2,726,991 | $11.44M |
RTW INVESTMENTS, LP↓ DEC | -2,718,049 | $61.15M |
Affinity Asset Advisors, LLC↓ DEC | -2,300,000 | $4.47M |
CITADEL ADVISORS LLC↓ DEC | -1,449,620 | $2.27M |
Siren, L.L.C.↓ DEC | -1,300,000 | $39.47M |
Invesco Ltd.↓ DEC | -964,759 | $1.65M |
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND↓ DEC | -838,699 | $12.89M |
SUPERSTRING CAPITAL MANAGEMENT LP↓ DEC | -722,499 | $1.15M |
GordonMD Global Investments LP↓ DEC | -593,351 | $22.22M |