第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
TCG Crossover Management, LLCCIK 0001839948 | 1,473,101 | $42.91M | +1,473,101 | NEW |
Boxer Capital Management, LLCCIK 0002018299 | 766,318 | $22.32M | +350,168 | ↑ INC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 731,138 | $21.30M | +9,872 | ↑ INC |
Venrock Adviser, LLCCIK 0001615982 | 632,931 | $18.44M | – | no_change |
Spruce Street Capital LPCIK 0002050194 | 432,040 | $12.59M | – | no_change |
BRAIDWELL LPCIK 0001920938 | 396,100 | $11.54M | -73,900 | ↓ DEC |
5AM Venture Management, LLCCIK 0001799883 | 387,500 | $11.29M | – | no_change |
Kalehua Capital Management LLCCIK 0002106181 | 385,178 | $11.22M | – | no_change |
Vestal Point Capital, LPCIK 0001974915 | 338,611 | $9.86M | +338,611 | NEW |
Vivo Capital, LLCCIK 0001674712 | 260,000 | $7.57M | – | no_change |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 229,393 | $6.68M | +229,393 | NEW |
Woodline Partners LPCIK 0001784547 | 227,848 | $6.64M | -2,724 | ↓ DEC |
BALYASNY ASSET MANAGEMENT L.P.CIK 0001218710 | 203,888 | $5.94M | +13,399 | ↑ INC |
STEMPOINT CAPITAL LPCIK 0001952142 | 195,981 | $5.71M | -423,785 | ↓ DEC |
Ikarian Capital, LLCCIK 0001778253 | 173,107 | $5.04M | +107,319 | ↑ INC |
ACUTA CAPITAL PARTNERS, LLCCIK 0001582844 | 172,847 | $5.04M | -5,568 | ↓ DEC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 169,092 | $4.93M | +169,092 | NEW |
AMERIPRISE FINANCIAL INCCIK 0000820027 | 159,711 | $4.65M | +94,023 | ↑ INC |
SILVERARC CAPITAL MANAGEMENT, LLCCIK 0001816307 | 144,255 | $4.20M | -13,068 | ↓ DEC |
REGENTS OF THE UNIVERSITY OF CALIFORNIACIK 0000315054 | 133,207 | $3.88M | – | no_change |
Euclidean Capital LLCCIK 0001825034 | 87,696 | $2.55M | – | no_change |
FRED ALGER MANAGEMENT, LLCCIK 0000003520 | 71,697 | $2.09M | -27,863 | ↓ DEC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 65,849 | $1.92M | -1,146 | ↓ DEC |
Eversept Partners, LPCIK 0001697013 | 58,624 | $1.71M | -36,662 | ↓ DEC |
ArrowMark Colorado Holdings LLCCIK 0001483859 | 55,123 | $1.61M | – | no_change |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
TCG Crossover Management, LLCNEW | +1,473,101 | $42.91M |
Boxer Capital Management, LLC↑ INC | +350,168 | $22.32M |
Vestal Point Capital, LPNEW | +338,611 | $9.86M |
PERCEPTIVE ADVISORS LLCNEW | +229,393 | $6.68M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +169,092 | $4.93M |
Ikarian Capital, LLC↑ INC | +107,319 | $5.04M |
AMERIPRISE FINANCIAL INC↑ INC | +94,023 | $4.65M |
TWO SIGMA INVESTMENTS, LPNEW | +39,482 | $1.15M |
VANGUARD FIDUCIARY TRUST CONEW | +35,390 | $1.03M |
BOOTHBAY FUND MANAGEMENT, LLC↑ INC | +28,992 | $1.38M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
STEMPOINT CAPITAL LP↓ DEC | -423,785 | $5.71M |
Stonepine Capital Management, LLC↓ DEC | -80,626 | $961.44K |
BRAIDWELL LP↓ DEC | -73,900 | $11.54M |
Eversept Partners, LP↓ DEC | -36,662 | $1.71M |
FRED ALGER MANAGEMENT, LLC↓ DEC | -27,863 | $2.09M |
JANE STREET GROUP, LLC↓ DEC | -20,531 | $206.56K |
MORGAN STANLEY↓ DEC | -14,515 | $653.85K |
SILVERARC CAPITAL MANAGEMENT, LLC↓ DEC | -13,068 | $4.20M |
683 Capital Management, LLC↓ DEC | -8,999 | $961.29K |
ACUTA CAPITAL PARTNERS, LLC↓ DEC | -5,568 | $5.04M |