第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
TCG Crossover Management, LLCCIK 0001839948 | 3,033,560 | $15.99M | – | no_change |
Siren, L.L.C.CIK 0002005245 | 2,911,438 | $15.34M | – | no_change |
Redmile Group, LLCCIK 0001425738 | 2,164,777 | $11.41M | – | no_change |
CITADEL ADVISORS LLCCIK 0001423053 | 1,246,107 | $6.57M | +987,246 | ↑ INC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 1,074,191 | $5.66M | +414,599 | ↑ INC |
GREAT POINT PARTNERS LLCCIK 0001281446 | 1,020,489 | $5.38M | +212,457 | ↑ INC |
Nextech Invest, Ltd.CIK 0001595430 | 952,400 | $5.02M | – | no_change |
Tetragon Partners GP LtdCIK 0001515070 | 630,161 | $3.32M | +264,792 | ↑ INC |
5AM Venture Management, LLCCIK 0001799883 | 476,200 | $2.51M | – | no_change |
Ikarian Capital, LLCCIK 0001778253 | 865,784 | $1.73M | – | no_change |
Jones Hill Capital LPCIK 0002102314 | 301,604 | $1.59M | +301,604 | NEW |
UBS Group AGCIK 0001610520 | 246,937 | $1.30M | +39,424 | ↑ INC |
BOOTHBAY FUND MANAGEMENT, LLCCIK 0001549230 | 209,088 | $1.10M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 204,777 | $1.08M | +131,624 | ↑ INC |
BANK OF MONTREAL /CAN/CIK 0000927971 | 202,901 | $1.07M | +42,427 | ↑ INC |
ADAR1 Capital Management, LLCCIK 0001940272 | 172,157 | $907.27K | +148,514 | ↑ INC |
MARSHALL WACE, LLPCIK 0001318757 | 169,616 | $893.88K | +13,936 | ↑ INC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 154,381 | $813.59K | +112,515 | ↑ INC |
BNP PARIBAS FINANCIAL MARKETSCIK 0001166588 | 147,668 | $778.21K | +135,641 | ↑ INC |
Ishara Investments LPCIK 0002111609 | 140,500 | $740.43K | -99,500 | ↓ DEC |
HSBC HOLDINGS PLCCIK 0000873630 | 122,834 | $639.97K | -50,000 | ↓ DEC |
Point72 Asset Management, L.P.CIK 0001603466 | 119,711 | $630.88K | +5,641 | ↑ INC |
XTX Topco LtdCIK 0001828301 | 106,002 | $558.63K | +94,284 | ↑ INC |
Qube Research & Technologies LtdCIK 0001729829 | 104,555 | $551.00K | +69,593 | ↑ INC |
M28 Capital Management LPCIK 0001807489 | 101,203 | $533.34K | -83,897 | ↓ DEC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
CITADEL ADVISORS LLC↑ INC | +987,246 | $6.57M |
MILLENNIUM MANAGEMENT LLC↑ INC | +414,599 | $5.66M |
Jones Hill Capital LPNEW | +301,604 | $1.59M |
Tetragon Partners GP Ltd↑ INC | +264,792 | $3.32M |
GREAT POINT PARTNERS LLC↑ INC | +212,457 | $5.38M |
ADAR1 Capital Management, LLC↑ INC | +148,514 | $907.27K |
BNP PARIBAS FINANCIAL MARKETS↑ INC | +135,641 | $778.21K |
BlackRock, Inc.↑ INC | +131,624 | $1.08M |
SUSQUEHANNA INTERNATIONAL GROUP, LLP↑ INC | +112,515 | $813.59K |
XTX Topco Ltd↑ INC | +94,284 | $558.63K |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
MORGAN STANLEY↓ DEC | -259,144 | $345.11K |
Ishara Investments LP↓ DEC | -99,500 | $740.43K |
M28 Capital Management LP↓ DEC | -83,897 | $533.34K |
HSBC HOLDINGS PLC↓ DEC | -50,000 | $639.97K |
TWO SIGMA INVESTMENTS, LP↓ DEC | -23,141 | $85.39K |
China Universal Asset Management Co., Ltd.↓ DEC | -5,318 | $43.92K |
SIMPLEX TRADING, LLC↓ DEC | -3,379 | $3.23K |
BARCLAYS PLC↓ DEC | -2,128 | $15.48K |
GAMMA Investing LLC↓ DEC | -747 | $49.35K |
JPMORGAN CHASE & CO↓ DEC | -306 | $38.03K |