第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
5AM Venture Management, LLCCIK 0001799883 | 9,681,763 | $5.95M | – | no_change |
Versant Venture Management, LLCCIK 0001560009 | 2,007,704 | $1.23M | – | no_change |
BAKER BROS. ADVISORS LPCIK 0001263508 | 1,575,243 | $968.14K | +124,605 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 764,457 | $470.14K | +764,457 | NEW |
SPHERA FUNDS MANAGEMENT LTD.CIK 0001496201 | 678,928 | $417.27K | +200,000 | ↑ INC |
BlackRock, Inc.CIK 0002012383 | 286,131 | $175.85K | +4,290 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 277,256 | $170.45K | +67,105 | ↑ INC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 258,200 | $158.69K | -122,278 | ↓ DEC |
PLATINUM INVESTMENT MANAGEMENT LTDCIK 0001256071 | 233,095 | $143.26K | – | no_change |
VANGUARD FIDUCIARY TRUST COCIK 0000933478 | 104,229 | $64.10K | +104,229 | NEW |
CITADEL ADVISORS LLCCIK 0001423053 | 98,900 | $60.78K | +16,200 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 75,326 | $46.30K | – | no_change |
UBS Group AGCIK 0001610520 | 45,762 | $28.14K | +32,476 | ↑ INC |
XTX Topco LtdCIK 0001828301 | 40,919 | $25.15K | -12,121 | ↓ DEC |
TWO SIGMA INVESTMENTS, LPCIK 0001179392 | 25,684 | $15.79K | -26,022 | ↓ DEC |
Engineers Gate Manager LPCIK 0001620220 | 20,194 | $12.41K | -2,944 | ↓ DEC |
NORTHERN TRUST CORPCIK 0000073124 | 20,142 | $12.38K | – | no_change |
BARCLAYS PLCCIK 0000312069 | 18,089 | $11.12K | -3,162 | ↓ DEC |
GROUP ONE TRADING LLCCIK 0000932540 | 7,205 | $4.43K | -10,492 | ↓ DEC |
Vanguard Global Advisers, LLCCIK 0001811242 | 4,557 | $2.80K | +4,557 | NEW |
GROUP ONE TRADING LLCCIK 0000932540 | 4,000 | $2.46K | +3,500 | ↑ INC |
MORGAN STANLEYCIK 0000895421 | 2,549 | $1.57K | -1,720 | ↓ DEC |
FEDERATED HERMES, INC.CIK 0001056288 | 1,158 | $712.00 | – | no_change |
OSAIC HOLDINGS, INC.CIK 0001677044 | 600 | $364.00 | +598 | ↑ INC |
NATIONAL BANK OF CANADA /FI/CIK 0000926171 | 400 | $242.00 | – | no_change |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +764,457 | $470.14K |
SPHERA FUNDS MANAGEMENT LTD.↑ INC | +200,000 | $417.27K |
BAKER BROS. ADVISORS LP↑ INC | +124,605 | $968.14K |
VANGUARD FIDUCIARY TRUST CONEW | +104,229 | $64.10K |
GEODE CAPITAL MANAGEMENT, LLC↑ INC | +67,105 | $170.45K |
UBS Group AG↑ INC | +32,476 | $28.14K |
CITADEL ADVISORS LLC↑ INC | +16,200 | $60.78K |
Vanguard Global Advisers, LLCNEW | +4,557 | $2.80K |
BlackRock, Inc.↑ INC | +4,290 | $175.85K |
GROUP ONE TRADING LLC↑ INC | +3,500 | $2.46K |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
MILLENNIUM MANAGEMENT LLC↓ DEC | -122,278 | $158.69K |
TWO SIGMA INVESTMENTS, LP↓ DEC | -26,022 | $15.79K |
XTX Topco Ltd↓ DEC | -12,121 | $25.15K |
GROUP ONE TRADING LLC↓ DEC | -10,492 | $4.43K |
BARCLAYS PLC↓ DEC | -3,162 | $11.12K |
Engineers Gate Manager LP↓ DEC | -2,944 | $12.41K |
MORGAN STANLEY↓ DEC | -1,720 | $1.57K |
NFSG Corp↓ DEC | -17 | $1.00 |