第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
FMR LLCCIK 0000315066 | 7,168,939 | $224.32M | +57,074 | ↑ INC |
TRV GP V, LLCCIK 0001990717 | 7,135,233 | $223.26M | – | no_change |
ARCH Venture Management, LLCCIK 0001274403 | 3,728,738 | $116.67M | – | no_change |
Capital International InvestorsCIK 0001562230 | 3,097,973 | $96.94M | -304,556 | ↓ DEC |
Cormorant Asset Management, LPCIK 0001583977 | 2,957,521 | $92.54M | -70,000 | ↓ DEC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 2,942,251 | $92.06M | -59,628 | ↓ DEC |
BlackRock, Inc.CIK 0002012383 | 2,505,955 | $78.41M | +74,093 | ↑ INC |
Sofinnova Investments, Inc.CIK 0001631134 | 1,904,408 | $59.59M | – | no_change |
JOHNSON & JOHNSONCIK 0000200406 | 1,784,517 | $55.84M | – | no_change |
BAKER BROS. ADVISORS LPCIK 0001263508 | 1,547,090 | $48.41M | – | no_change |
Vestal Point Capital, LPCIK 0001974915 | 1,436,229 | $44.94M | +326,229 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 1,325,082 | $41.46M | +1,325,082 | NEW |
TRV GP VI, LLCCIK 0001990716 | 969,218 | $30.33M | – | no_change |
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLCCIK 0000861177 | 918,866 | $28.75M | -33,505 | ↓ DEC |
STATE STREET CORPCIK 0000093751 | 759,552 | $23.77M | +44,731 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 721,622 | $22.58M | +26,888 | ↑ INC |
ALLIANCEBERNSTEIN L.P.CIK 0001109448 | 727,843 | $22.08M | -60,568 | ↓ DEC |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 673,923 | $21.09M | – | no_change |
Siren, L.L.C.CIK 0002005245 | 641,469 | $20.07M | -67,000 | ↓ DEC |
Capital World InvestorsCIK 0001422849 | 536,607 | $16.79M | +536,607 | NEW |
Sio Capital Management, LLCCIK 0001482416 | 366,809 | $11.48M | +181,544 | ↑ INC |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 320,909 | $10.04M | +320,909 | NEW |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 319,552 | $10.00M | +117,727 | ↑ INC |
KENNEDY CAPITAL MANAGEMENT LLCCIK 0000884589 | 257,431 | $8.06M | +78,694 | ↑ INC |
Burkehill Global Management, LPCIK 0001904549 | 250,000 | $7.82M | – | no_change |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +1,325,082 | $41.46M |
Capital World InvestorsNEW | +536,607 | $16.79M |
T. Rowe Price Investment Management, Inc.↑ INC | +385,831 | $19.42K |
Vestal Point Capital, LP↑ INC | +326,229 | $44.94M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +320,909 | $10.04M |
VANGUARD FIDUCIARY TRUST CONEW | +189,253 | $5.92M |
Candriam S.C.A.NEW | +185,925 | $5.82M |
Sio Capital Management, LLC↑ INC | +181,544 | $11.48M |
DIMENSIONAL FUND ADVISORS LP↑ INC | +141,011 | $7.02M |
MILLENNIUM MANAGEMENT LLC↑ INC | +117,727 | $10.00M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
Capital International Investors↓ DEC | -304,556 | $96.94M |
PRUDENTIAL FINANCIAL INC↓ DEC | -140,152 | $3.59M |
RENAISSANCE TECHNOLOGIES LLC↓ DEC | -109,114 | $303.51K |
Invesco Ltd.↓ DEC | -95,363 | $5.37M |
UBS Group AG↓ DEC | -74,602 | $4.75M |
Soleus Capital Management, L.P.↓ DEC | -70,000 | $312.90K |
Cormorant Asset Management, LP↓ DEC | -70,000 | $92.54M |
Siren, L.L.C.↓ DEC | -67,000 | $20.07M |
ALLIANCEBERNSTEIN L.P.↓ DEC | -60,568 | $22.08M |
GOLDMAN SACHS GROUP INC↓ DEC | -59,628 | $92.06M |