第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
FMR LLCCIK 0000315066 | 10,386,845 | $154.87M | +5,363,753 | ↑ INC |
Paradigm Biocapital Advisors LPCIK 0001855655 | 8,020,576 | $119.59M | +476,404 | ↑ INC |
Bain Capital Life Sciences Investors, LLCCIK 0001703031 | 7,473,238 | $111.43M | -1,035,403 | ↓ DEC |
BlackRock, Inc.CIK 0002012383 | 5,652,135 | $84.27M | +88,875 | ↑ INC |
BVF INC/ILCIK 0001056807 | 5,295,893 | $78.96M | – | no_change |
Siren, L.L.C.CIK 0002005245 | 4,756,949 | $70.93M | +1,456,249 | ↑ INC |
Cormorant Asset Management, LPCIK 0001583977 | 4,400,000 | $65.60M | +1,650,000 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 3,937,831 | $58.71M | +2,053,432 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 3,083,517 | $45.98M | +3,083,517 | NEW |
JENNISON ASSOCIATES LLCCIK 0000053417 | 1,822,123 | $27.17M | +858,126 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 1,544,417 | $23.03M | +286,976 | ↑ INC |
Woodline Partners LPCIK 0001784547 | 1,482,030 | $22.10M | +100 | ↑ INC |
Lightspeed Management Company, L.L.C.CIK 0001702122 | 1,355,299 | $20.21M | -575,595 | ↓ DEC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 1,252,689 | $18.68M | +434,800 | ↑ INC |
FRANKLIN RESOURCES INCCIK 0000038777 | 1,218,957 | $18.17M | -1,257,708 | ↓ DEC |
MORGAN STANLEYCIK 0000895421 | 1,215,690 | $18.13M | +549,887 | ↑ INC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 1,207,382 | $18.00M | +303,258 | ↑ INC |
TWO SIGMA INVESTMENTS, LPCIK 0001179392 | 1,169,421 | $17.44M | +775,763 | ↑ INC |
Ikarian Capital, LLCCIK 0001778253 | 1,148,081 | $17.12M | +189,427 | ↑ INC |
CITADEL ADVISORS LLCCIK 0001423053 | 1,106,332 | $16.50M | -268,075 | ↓ DEC |
DIMENSIONAL FUND ADVISORS LPCIK 0000354204 | 1,082,434 | $16.13M | +123,790 | ↑ INC |
Squarepoint Ops LLCCIK 0001642575 | 858,552 | $12.80M | +529,872 | ↑ INC |
KINGDON CAPITAL MANAGEMENT, L.L.C.CIK 0001000097 | 855,000 | $12.75M | -98,600 | ↓ DEC |
First Turn Management, LLCCIK 0001993440 | 768,662 | $11.46M | +150,948 | ↑ INC |
Candriam S.C.A.CIK 0001537014 | 759,513 | $11.32M | +80,029 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
FMR LLC↑ INC | +5,363,753 | $154.87M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +3,083,517 | $45.98M |
STATE STREET CORP↑ INC | +2,053,432 | $58.71M |
Cormorant Asset Management, LP↑ INC | +1,650,000 | $65.60M |
Siren, L.L.C.↑ INC | +1,456,249 | $70.93M |
Duquesne Family Office LLCNEW | +986,827 | $14.71K |
JENNISON ASSOCIATES LLC↑ INC | +858,126 | $27.17M |
TWO SIGMA INVESTMENTS, LP↑ INC | +775,763 | $17.44M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +593,031 | $8.84M |
MORGAN STANLEY↑ INC | +549,887 | $18.13M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
FRANKLIN RESOURCES INC↓ DEC | -1,257,708 | $18.17M |
Vestal Point Capital, LP↓ DEC | -1,221,449 | $6.39M |
Bain Capital Life Sciences Investors, LLC↓ DEC | -1,035,403 | $111.43M |
Lightspeed Management Company, L.L.C.↓ DEC | -575,595 | $20.21M |
MILLENNIUM MANAGEMENT LLC↓ DEC | -315,555 | $2.73M |
Pictet Asset Management Holding SA↓ DEC | -285,545 | $3.24M |
CITADEL ADVISORS LLC↓ DEC | -268,075 | $16.50M |
STEMPOINT CAPITAL LP↓ DEC | -256,287 | $3.75K |
Point72 Asset Management, L.P.↓ DEC | -212,283 | $1.64M |
AMERIPRISE FINANCIAL INC↓ DEC | -147,267 | $855.27K |