第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
Deep Track Capital, LPCIK 0001856083 | 3,352,804 | $82.68M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 2,470,845 | $60.93M | +231,911 | ↑ INC |
TCG Crossover Management, LLCCIK 0001839948 | 1,839,489 | $45.28M | +94,474 | ↑ INC |
Commodore Capital LPCIK 0001831942 | 1,500,000 | $36.99M | – | no_change |
Caligan Partners LPCIK 0001727492 | 1,438,070 | $34.63M | +1,438,070 | NEW |
Spruce Street Capital LPCIK 0002050194 | 1,376,159 | $33.64M | +370,566 | ↑ INC |
JPMORGAN CHASE & COCIK 0000019617 | 1,427,568 | $33.19M | -183,914 | ↓ DEC |
Trails Edge Capital Partners, LPCIK 0002077247 | 1,319,362 | $32.54M | -76,246 | ↓ DEC |
BALYASNY ASSET MANAGEMENT L.P.CIK 0001218710 | 923,694 | $22.78M | +26,888 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 894,653 | $22.06M | +894,653 | NEW |
Alyeska Investment Group, L.P.CIK 0001453072 | 863,947 | $21.28M | +188,947 | ↑ INC |
Vivo Capital, LLCCIK 0001674712 | 800,000 | $19.73M | – | no_change |
Nan Fung Group Holdings LtdCIK 0001782539 | 630,657 | $15.55M | +330,657 | ↑ INC |
JENNISON ASSOCIATES LLCCIK 0000053417 | 538,216 | $13.27M | -283,636 | ↓ DEC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 518,228 | $12.78M | +76,774 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 504,373 | $12.44M | +254,343 | ↑ INC |
CITADEL ADVISORS LLCCIK 0001423053 | 416,906 | $10.28M | +9,238 | ↑ INC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 363,799 | $8.97M | +60,684 | ↑ INC |
GREAT POINT PARTNERS LLCCIK 0001281446 | 300,000 | $7.40M | +300,000 | NEW |
FMR LLCCIK 0000315066 | 222,508 | $5.49M | +643 | ↑ INC |
BAKER BROS. ADVISORS LPCIK 0001263508 | 200,000 | $4.93M | – | no_change |
CHARLES SCHWAB INVESTMENT MANAGEMENT INCCIK 0000884546 | 186,095 | $4.59M | +8,479 | ↑ INC |
HighVista Strategies LLCCIK 0001335325 | 173,595 | $4.28M | +33,488 | ↑ INC |
VANGUARD FIDUCIARY TRUST COCIK 0000933478 | 157,426 | $3.88M | +157,426 | NEW |
NORTHERN TRUST CORPCIK 0000073124 | 154,398 | $3.81M | +10,432 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
Caligan Partners LPNEW | +1,438,070 | $34.63M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +894,653 | $22.06M |
Spruce Street Capital LP↑ INC | +370,566 | $33.64M |
Nan Fung Group Holdings Ltd↑ INC | +330,657 | $15.55M |
GREAT POINT PARTNERS LLCNEW | +300,000 | $7.40M |
STATE STREET CORP↑ INC | +254,343 | $12.44M |
BlackRock, Inc.↑ INC | +231,911 | $60.93M |
Alyeska Investment Group, L.P.↑ INC | +188,947 | $21.28M |
VANGUARD FIDUCIARY TRUST CONEW | +157,426 | $3.88M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +112,497 | $2.77M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
MILLENNIUM MANAGEMENT LLC↓ DEC | -401,203 | $3.38M |
WELLINGTON MANAGEMENT GROUP LLP↓ DEC | -292,017 | $1.30M |
JENNISON ASSOCIATES LLC↓ DEC | -283,636 | $13.27M |
JPMORGAN CHASE & CO↓ DEC | -183,914 | $33.19M |
AMERIPRISE FINANCIAL INC↓ DEC | -85,237 | $2.67M |
Trails Edge Capital Partners, LP↓ DEC | -76,246 | $32.54M |
BANK OF AMERICA CORP /DE/↓ DEC | -27,140 | $409.80K |
BARCLAYS PLC↓ DEC | -25,685 | $111.71K |
ACUTA CAPITAL PARTNERS, LLC↓ DEC | -1,081 | $713.14K |
Focus Partners Wealth↓ DEC | -280 | $488.64K |