第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
FMR LLCCIK 0000315066 | 4,373,987 | $1.13B | +24,359 | ↑ INC |
BlackRock, Inc.CIK 0002012383 | 3,940,456 | $1.02B | +2,639 | ↑ INC |
Avoro Capital Advisors LLCCIK 0001633313 | 2,888,888 | $746.26M | – | no_change |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 1,456,727 | $376.30M | +1,456,727 | NEW |
STATE STREET CORPCIK 0000093751 | 1,314,434 | $339.54M | -27,869 | ↓ DEC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 1,165,324 | $301.03M | +1,165,324 | NEW |
Soleus Capital Management, L.P.CIK 0001802630 | 1,153,087 | $297.87M | +212,028 | ↑ INC |
Capital World InvestorsCIK 0001422849 | 824,720 | $213.04M | +15,220 | ↑ INC |
Redmile Group, LLCCIK 0001425738 | 673,505 | $173.98M | -4,200 | ↓ DEC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 643,975 | $166.38M | +32,097 | ↑ INC |
Hood River Capital Management LLCCIK 0001578177 | 619,586 | $160.05M | +6,284 | ↑ INC |
Bellevue Group AGCIK 0001674546 | 481,785 | $124.45M | +71,462 | ↑ INC |
Frazier Life Sciences Management, L.P.CIK 0001892134 | 481,307 | $124.33M | -7,153 | ↓ DEC |
DIMENSIONAL FUND ADVISORS LPCIK 0000354204 | 468,990 | $121.13M | -23,978 | ↓ DEC |
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLCCIK 0001644956 | 407,178 | $105.18M | +30,838 | ↑ INC |
FIRST TRUST ADVISORS LPCIK 0001125816 | 350,521 | $90.55M | +105,245 | ↑ INC |
BANK OF AMERICA CORP /DE/CIK 0000070858 | 260,647 | $67.33M | +69,840 | ↑ INC |
NORTHERN TRUST CORPCIK 0000073124 | 252,463 | $65.22M | +5,020 | ↑ INC |
Invesco Ltd.CIK 0000914208 | 251,373 | $64.93M | +191,365 | ↑ INC |
CHARLES SCHWAB INVESTMENT MANAGEMENT INCCIK 0000884546 | 241,986 | $62.51M | -788 | ↓ DEC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 214,949 | $55.53M | -78,576 | ↓ DEC |
MORGAN STANLEYCIK 0000895421 | 209,082 | $54.01M | -12,399 | ↓ DEC |
Caption Management, LLCCIK 0001706766 | 190,000 | $49.08M | +64,700 | ↑ INC |
BRAIDWELL LPCIK 0001920938 | 182,425 | $47.12M | -19,676 | ↓ DEC |
FRANKLIN RESOURCES INCCIK 0000038777 | 179,265 | $46.31M | +53,590 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +1,456,727 | $376.30M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +1,165,324 | $301.03M |
Soleus Capital Management, L.P.↑ INC | +212,028 | $297.87M |
Invesco Ltd.↑ INC | +191,365 | $64.93M |
VANGUARD FIDUCIARY TRUST CONEW | +179,161 | $46.28M |
FIRST TRUST ADVISORS LP↑ INC | +105,245 | $90.55M |
RAYMOND JAMES FINANCIAL INC↑ INC | +79,526 | $39.53M |
SUSQUEHANNA INTERNATIONAL GROUP, LLP↑ INC | +78,075 | $42.58M |
Bellevue Group AG↑ INC | +71,462 | $124.45M |
BANK OF AMERICA CORP /DE/↑ INC | +69,840 | $67.33M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
CITADEL ADVISORS LLC↓ DEC | -377,179 | $8.30M |
MARSHALL WACE, LLP↓ DEC | -115,411 | $17.65M |
GOLDMAN SACHS GROUP INC↓ DEC | -78,576 | $55.53M |
BARCLAYS PLC↓ DEC | -55,093 | $1.28M |
ORBIMED ADVISORS LLC↓ DEC | -50,700 | $17.85M |
Pictet Asset Management Holding SA↓ DEC | -45,903 | $28.59M |
Nuveen, LLC↓ DEC | -45,726 | $37.03M |
PRICE T ROWE ASSOCIATES INC /MD/↓ DEC | -44,881 | $125.31K |
JPMORGAN CHASE & CO↓ DEC | -35,519 | $24.47M |
Corient Private Wealth LLC↓ DEC | -34,767 | $818.45K |