第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
Samsara BioCapital, LLCCIK 0001744967 | 12,948,081 | $74.71M | – | no_change |
RTW INVESTMENTS, LPCIK 0001493215 | 1,300,000 | $7.50M | – | no_change |
Paradigm Biocapital Advisors LPCIK 0001855655 | 700,000 | $4.04M | – | no_change |
Alyeska Investment Group, L.P.CIK 0001453072 | 572,687 | $3.27M | +169,136 | ↑ INC |
Siren, L.L.C.CIK 0002005245 | 435,798 | $2.51M | – | no_change |
Ikarian Capital, LLCCIK 0001778253 | 360,000 | $2.08M | – | no_change |
Propel Bio Management, LLCCIK 0001969764 | 295,771 | $1.72M | +253,718 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 255,348 | $1.47M | +255,348 | NEW |
Kalehua Capital Management LLCCIK 0002106181 | 135,585 | $782.33K | -4,316 | ↓ DEC |
RAYMOND JAMES FINANCIAL INCCIK 0000720005 | 118,887 | $685.98K | +30,451 | ↑ INC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 110,503 | $637.60K | +76,200 | ↑ INC |
Woodline Partners LPCIK 0001784547 | 100,000 | $577.00K | – | no_change |
ADAR1 Capital Management, LLCCIK 0001940272 | 100,000 | $577.00K | – | no_change |
WHI TRUST Co LLCCIK 0002013902 | 97,493 | $562.53K | – | no_change |
BOOTHBAY FUND MANAGEMENT, LLCCIK 0001549230 | 92,261 | $532.35K | – | no_change |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 87,545 | $505.34K | +4,898 | ↑ INC |
Simplify Asset Management Inc.CIK 0001846368 | 87,426 | $504.45K | +67,352 | ↑ INC |
MARSHALL WACE, LLPCIK 0001318757 | 67,879 | $391.66K | -4,997 | ↓ DEC |
RENAISSANCE TECHNOLOGIES LLCCIK 0001037389 | 66,151 | $381.69K | -21,600 | ↓ DEC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 59,534 | $343.51K | +34,611 | ↑ INC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 52,684 | $303.99K | +39,828 | ↑ INC |
683 Capital Management, LLCCIK 0001404574 | 45,000 | $259.65K | -35,590 | ↓ DEC |
Belpointe Asset Management LLCCIK 0001721242 | 40,000 | $230.80K | – | no_change |
Fortis Capital Advisors, LLCCIK 0001959790 | 40,000 | $230.80K | – | no_change |
Squarepoint Ops LLCCIK 0001642575 | 39,773 | $229.49K | +14,406 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +255,348 | $1.47M |
Propel Bio Management, LLC↑ INC | +253,718 | $1.72M |
Alyeska Investment Group, L.P.↑ INC | +169,136 | $3.27M |
GOLDMAN SACHS GROUP INC↑ INC | +76,200 | $637.60K |
Simplify Asset Management Inc.↑ INC | +67,352 | $504.45K |
SUSQUEHANNA INTERNATIONAL GROUP, LLP↑ INC | +39,828 | $303.99K |
VANGUARD FIDUCIARY TRUST CONEW | +36,717 | $211.86K |
MILLENNIUM MANAGEMENT LLC↑ INC | +34,611 | $343.51K |
RAYMOND JAMES FINANCIAL INC↑ INC | +30,451 | $685.98K |
Stonepine Capital Management, LLCNEW | +20,400 | $117.71K |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
683 Capital Management, LLC↓ DEC | -35,590 | $259.65K |
RENAISSANCE TECHNOLOGIES LLC↓ DEC | -21,600 | $381.69K |
MARSHALL WACE, LLP↓ DEC | -4,997 | $391.66K |
Kalehua Capital Management LLC↓ DEC | -4,316 | $782.33K |
BlackRock, Inc.↓ DEC | -2,411 | $207.97K |
Tower Research Capital LLC (TRC)↓ DEC | -2,014 | $802.00 |
BARCLAYS PLC↓ DEC | -785 | $30.47K |
FEDERATED HERMES, INC.↓ DEC | -544 | $196.00 |
ROYAL BANK OF CANADA↓ DEC | -10 | $1.00K |