第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
FEDERATED HERMES, INC.CIK 0001056288 | 1,765,516 | $45.73M | – | no_change |
FRED ALGER MANAGEMENT, LLCCIK 0000003520 | 1,273,965 | $33.00M | -187,006 | ↓ DEC |
ORBIMED ADVISORS LLCCIK 0001055951 | 1,196,955 | $31.00M | – | no_change |
Affinity Asset Advisors, LLCCIK 0001773195 | 1,011,890 | $26.21M | – | no_change |
MPM BioImpact LLCCIK 0001687078 | 1,000,682 | $25.92M | +1,000,682 | NEW |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 531,692 | $13.77M | +531,692 | NEW |
MORGAN STANLEYCIK 0000895421 | 500,298 | $12.96M | +429,767 | ↑ INC |
Cable Car Capital, LPCIK 0001699575 | 400,000 | $10.36M | – | no_change |
FMR LLCCIK 0000315066 | 340,695 | $8.82M | +29,730 | ↑ INC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 337,983 | $8.75M | +91,298 | ↑ INC |
Woodline Partners LPCIK 0001784547 | 331,987 | $8.60M | – | no_change |
CITADEL ADVISORS LLCCIK 0001423053 | 233,369 | $6.04M | +217,736 | ↑ INC |
AWM Investment Company, Inc.CIK 0001535264 | 200,000 | $5.18M | -36,821 | ↓ DEC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 190,794 | $4.94M | +137,880 | ↑ INC |
SPHERA FUNDS MANAGEMENT LTD.CIK 0001496201 | 184,984 | $4.79M | -885 | ↓ DEC |
MARSHALL WACE, LLPCIK 0001318757 | 150,307 | $3.89M | +114,010 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 125,442 | $3.25M | +833 | ↑ INC |
Ikarian Capital, LLCCIK 0001778253 | 118,972 | $3.08M | -181,028 | ↓ DEC |
AMERIPRISE FINANCIAL INCCIK 0000820027 | 111,788 | $2.90M | -41,239 | ↓ DEC |
Russell Investments Group, Ltd.CIK 0001692234 | 91,772 | $2.38M | +91,754 | ↑ INC |
Qube Research & Technologies LtdCIK 0001729829 | 85,969 | $2.23M | +53,782 | ↑ INC |
Candriam S.C.A.CIK 0001537014 | 84,803 | $2.20M | +84,803 | NEW |
Trexquant Investment LPCIK 0001633445 | 73,651 | $1.91M | +60,735 | ↑ INC |
VANGUARD FIDUCIARY TRUST COCIK 0000933478 | 72,095 | $1.87M | +72,095 | NEW |
BlackRock, Inc.CIK 0002012383 | 65,921 | $1.71M | +1,425 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
MPM BioImpact LLCNEW | +1,000,682 | $25.92M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +531,692 | $13.77M |
MORGAN STANLEY↑ INC | +429,767 | $12.96M |
CITADEL ADVISORS LLC↑ INC | +217,736 | $6.04M |
SUSQUEHANNA INTERNATIONAL GROUP, LLP↑ INC | +137,880 | $4.94M |
LORD, ABBETT & CO. LLCNEW | +114,635 | $2.97K |
MARSHALL WACE, LLP↑ INC | +114,010 | $3.89M |
Russell Investments Group, Ltd.↑ INC | +91,754 | $2.38M |
MILLENNIUM MANAGEMENT LLC↑ INC | +91,298 | $8.75M |
Candriam S.C.A.NEW | +84,803 | $2.20M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
FRED ALGER MANAGEMENT, LLC↓ DEC | -187,006 | $33.00M |
Ikarian Capital, LLC↓ DEC | -181,028 | $3.08M |
AMERIPRISE FINANCIAL INC↓ DEC | -41,239 | $2.90M |
AWM Investment Company, Inc.↓ DEC | -36,821 | $5.18M |
683 Capital Management, LLC↓ DEC | -20,000 | $518.00K |
TWO SIGMA INVESTMENTS, LP↓ DEC | -16,299 | $401.68K |
GOLDMAN SACHS GROUP INC↓ DEC | -14,550 | $1.38M |
BNP PARIBAS FINANCIAL MARKETS↓ DEC | -12,036 | $88.99K |
BARCLAYS PLC↓ DEC | -10,843 | $343.64K |
J. Goldman & Co LP↓ DEC | -6,626 | $1.40M |