第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
BlackRock, Inc.CIK 0002012383 | 11,699,870 | $212.12M | +509,032 | ↑ INC |
Atlas Venture Life Science Advisors, LLCCIK 0001917529 | 9,130,465 | $165.54M | – | no_change |
FMR LLCCIK 0000315066 | 8,908,980 | $161.52M | +2,339,059 | ↑ INC |
Orbis Allan Gray LtdCIK 0001663865 | 6,762,231 | $122.60M | +1,960,303 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 6,653,746 | $120.63M | -38,999 | ↓ DEC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 6,405,069 | $116.12M | +6,405,069 | NEW |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 4,668,839 | $84.65M | +1,189,895 | ↑ INC |
FCPM III SERVICES B.V.CIK 0002013410 | 4,644,386 | $84.20M | -818,460 | ↓ DEC |
TCG Crossover Management, LLCCIK 0001839948 | 4,615,144 | $83.67M | – | no_change |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 4,162,041 | $75.46M | +4,162,041 | NEW |
Vestal Point Capital, LPCIK 0001974915 | 4,000,000 | $72.52M | +3,880,000 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 3,504,114 | $63.54M | +240,685 | ↑ INC |
ARMISTICE CAPITAL, LLCCIK 0001601086 | 3,175,110 | $57.56M | -74,598 | ↓ DEC |
Frazier Life Sciences Management, L.P.CIK 0001892134 | 3,153,082 | $57.17M | – | no_change |
JPMORGAN CHASE & COCIK 0000019617 | 3,253,473 | $55.60M | -296,436 | ↓ DEC |
ORBIMED ADVISORS LLCCIK 0001055951 | 2,917,884 | $52.90M | +715,700 | ↑ INC |
Siren, L.L.C.CIK 0002005245 | 2,229,125 | $40.41M | -1,273,816 | ↓ DEC |
Venrock Adviser, LLCCIK 0001615982 | 2,173,913 | $39.41M | – | no_change |
FRANKLIN RESOURCES INCCIK 0000038777 | 2,009,082 | $36.42M | +2,444 | ↑ INC |
Deep Track Capital, LPCIK 0001856083 | 2,000,000 | $36.26M | -650,000 | ↓ DEC |
SAMLYN CAPITAL, LLCCIK 0001421097 | 1,922,543 | $34.86M | +429,468 | ↑ INC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 1,723,116 | $31.24M | -560,075 | ↓ DEC |
BRAIDWELL LPCIK 0001920938 | 1,681,998 | $30.49M | +203,669 | ↑ INC |
Palo Alto Investors LPCIK 0001306923 | 1,652,972 | $29.97M | +180,775 | ↑ INC |
Sofinnova Investments, Inc.CIK 0001631134 | 1,633,897 | $29.62M | -620,264 | ↓ DEC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
T. Rowe Price Investment Management, Inc.↑ INC | +27,915,233 | $558.15K |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +6,405,069 | $116.12M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +4,162,041 | $75.46M |
Vestal Point Capital, LP↑ INC | +3,880,000 | $72.52M |
FMR LLC↑ INC | +2,339,059 | $161.52M |
Orbis Allan Gray Ltd↑ INC | +1,960,303 | $122.60M |
Fiera Capital CorpNEW | +1,380,620 | $25.03M |
PERCEPTIVE ADVISORS LLC↑ INC | +1,189,895 | $84.65M |
VANGUARD FIDUCIARY TRUST CONEW | +947,438 | $17.18M |
DIMENSIONAL FUND ADVISORS LP↑ INC | +853,515 | $17.24M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
Siren, L.L.C.↓ DEC | -1,273,816 | $40.41M |
Vivo Capital, LLC↓ DEC | -1,057,494 | $28.24M |
CITADEL ADVISORS LLC↓ DEC | -986,680 | $4.36M |
Saturn V Capital Management LP↓ DEC | -822,007 | $17.52M |
FCPM III SERVICES B.V.↓ DEC | -818,460 | $84.20M |
MILLENNIUM MANAGEMENT LLC↓ DEC | -745,841 | $2.87M |
Man Group plc↓ DEC | -650,781 | $1.73M |
Deep Track Capital, LP↓ DEC | -650,000 | $36.26M |
Sofinnova Investments, Inc.↓ DEC | -620,264 | $29.62M |
MARSHALL WACE, LLP↓ DEC | -593,832 | $1.51M |