第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
MPM BioImpact LLCCIK 0001687078 | 5,213,361 | $108.91M | +4,216,536 | ↑ INC |
Vivo Capital, LLCCIK 0001674712 | 2,667,569 | $55.73M | +205,943 | ↑ INC |
Artisan Partners Limited PartnershipCIK 0001466153 | 2,219,386 | $46.36M | -1,089,669 | ↓ DEC |
Siren, L.L.C.CIK 0002005245 | 1,857,362 | $38.80M | – | no_change |
BAKER BROS. ADVISORS LPCIK 0001263508 | 1,461,425 | $30.53M | – | no_change |
ADAR1 Capital Management, LLCCIK 0001940272 | 1,012,866 | $21.16M | +1,012,866 | NEW |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 964,391 | $20.15M | +964,391 | NEW |
Patient Square Capital LPCIK 0001819257 | 693,534 | $14.49M | +334,484 | ↑ INC |
Octagon Capital Advisors LPCIK 0001839435 | 574,200 | $12.00M | – | no_change |
Redmile Group, LLCCIK 0001425738 | 491,340 | $10.26M | -58,500 | ↓ DEC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 318,959 | $6.66M | -321,926 | ↓ DEC |
Atika Capital Management LLCCIK 0001599731 | 271,300 | $5.67M | +64,419 | ↑ INC |
Elmind Capital, LPCIK 0002052213 | 265,000 | $5.54M | +265,000 | NEW |
BALYASNY ASSET MANAGEMENT L.P.CIK 0001218710 | 233,429 | $4.88M | -1,594 | ↓ DEC |
AMERIPRISE FINANCIAL INCCIK 0000820027 | 231,417 | $4.83M | +231,417 | NEW |
Yiheng Capital Management, L.P.CIK 0001447228 | 170,142 | $3.55M | -469,627 | ↓ DEC |
NEW YORK STATE COMMON RETIREMENT FUNDCIK 0000810265 | 168,180 | $3.51M | -55,006 | ↓ DEC |
BOOTHBAY FUND MANAGEMENT, LLCCIK 0001549230 | 163,401 | $3.41M | – | no_change |
MORGAN STANLEYCIK 0000895421 | 146,116 | $3.05M | +23,621 | ↑ INC |
Russell Investments Group, Ltd.CIK 0001692234 | 128,560 | $2.69M | +128,560 | NEW |
Ikarian Capital, LLCCIK 0001778253 | 525,000 | $2.20M | – | no_change |
Dorsey Wright & AssociatesCIK 0001376772 | 102,550 | $2.14M | +102,550 | NEW |
Ishara Investments LPCIK 0002111609 | 102,500 | $2.14M | +102,500 | NEW |
ENVESTNET ASSET MANAGEMENT INCCIK 0001407543 | 95,714 | $2.00M | +73,322 | ↑ INC |
UBS Group AGCIK 0001610520 | 79,537 | $1.66M | -165,325 | ↓ DEC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
MPM BioImpact LLC↑ INC | +4,216,536 | $108.91M |
ADAR1 Capital Management, LLCNEW | +1,012,866 | $21.16M |
PERCEPTIVE ADVISORS LLCNEW | +964,391 | $20.15M |
Duquesne Family Office LLCNEW | +383,363 | $8.01K |
Patient Square Capital LP↑ INC | +334,484 | $14.49M |
Elmind Capital, LPNEW | +265,000 | $5.54M |
AMERIPRISE FINANCIAL INCNEW | +231,417 | $4.83M |
Vivo Capital, LLC↑ INC | +205,943 | $55.73M |
Russell Investments Group, Ltd.NEW | +128,560 | $2.69M |
Dorsey Wright & AssociatesNEW | +102,550 | $2.14M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
Artisan Partners Limited Partnership↓ DEC | -1,089,669 | $46.36M |
Yiheng Capital Management, L.P.↓ DEC | -469,627 | $3.55M |
MILLENNIUM MANAGEMENT LLC↓ DEC | -321,926 | $6.66M |
UBS Group AG↓ DEC | -165,325 | $1.66M |
Redmile Group, LLC↓ DEC | -58,500 | $10.26M |
NEW YORK STATE COMMON RETIREMENT FUND↓ DEC | -55,006 | $3.51M |
SEI INVESTMENTS CO↓ DEC | -49,577 | $350.20K |
JPMORGAN CHASE & CO↓ DEC | -28,359 | $391.00 |
BARCLAYS PLC↓ DEC | -21,926 | $168.77K |
ExodusPoint Capital Management, LP↓ DEC | -15,673 | $241.03K |