第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
FMR LLCCIK 0000315066 | 23,122,748 | $889.99M | +35,781 | ↑ INC |
BlackRock, Inc.CIK 0002012383 | 16,045,014 | $617.57M | +3,070,423 | ↑ INC |
DEERFIELD MANAGEMENT COMPANY, L.P.CIK 0001009258 | 9,043,903 | $348.10M | – | no_change |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 7,333,333 | $282.26M | +7,333,333 | NEW |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 6,894,959 | $265.39M | +6,894,959 | NEW |
STATE STREET CORPCIK 0000093751 | 5,663,543 | $217.99M | +723,243 | ↑ INC |
Fairmount Funds Management LLCCIK 0001802528 | 5,503,418 | $211.83M | -3,500,000 | ↓ DEC |
RTW INVESTMENTS, LPCIK 0001493215 | 5,458,675 | $210.10M | -2,133,566 | ↓ DEC |
TCG Crossover Management, LLCCIK 0001839948 | 4,946,894 | $190.41M | -921,268 | ↓ DEC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 4,434,054 | $170.67M | +2,728,910 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 3,699,519 | $142.42M | +184,957 | ↑ INC |
WELLINGTON MANAGEMENT GROUP LLPCIK 0000902219 | 3,578,622 | $137.74M | +866,286 | ↑ INC |
Commodore Capital LPCIK 0001831942 | 2,888,007 | $111.16M | +691,162 | ↑ INC |
Invesco Ltd.CIK 0000914208 | 2,429,629 | $93.52M | +1,843,864 | ↑ INC |
Octagon Capital Advisors LPCIK 0001839435 | 2,350,000 | $90.45M | – | no_change |
Holocene Advisors, LPCIK 0001700574 | 2,250,196 | $86.61M | +1,071,988 | ↑ INC |
Sofinnova Investments, Inc.CIK 0001631134 | 2,113,551 | $81.35M | +139,926 | ↑ INC |
Venrock Adviser, LLCCIK 0001615982 | 2,000,000 | $76.98M | – | no_change |
CITADEL ADVISORS LLCCIK 0001423053 | 1,907,427 | $73.42M | +316,033 | ↑ INC |
Pictet Asset Management Holding SACIK 0001993888 | 1,798,768 | $68.83M | +1,686,292 | ↑ INC |
Siren, L.L.C.CIK 0002005245 | 1,709,279 | $65.79M | +80,000 | ↑ INC |
MARSHALL WACE, LLPCIK 0001318757 | 1,600,168 | $61.59M | -60,567 | ↓ DEC |
EMERALD ADVISERS, LLCCIK 0001015083 | 1,588,132 | $61.13M | +4,786 | ↑ INC |
Candriam S.C.A.CIK 0001537014 | 1,516,297 | $58.36M | +219,822 | ↑ INC |
Woodline Partners LPCIK 0001784547 | 1,509,557 | $58.10M | +690,775 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +7,333,333 | $282.26M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +6,894,959 | $265.39M |
BlackRock, Inc.↑ INC | +3,070,423 | $617.57M |
GOLDMAN SACHS GROUP INC↑ INC | +2,728,910 | $170.67M |
Jefferies Financial Group Inc.NEW | +2,411,000 | $2.95M |
Invesco Ltd.↑ INC | +1,843,864 | $93.52M |
Pictet Asset Management Holding SA↑ INC | +1,686,292 | $68.83M |
LORD, ABBETT & CO. LLC↑ INC | +1,310,733 | $122.45K |
Holocene Advisors, LP↑ INC | +1,071,988 | $86.61M |
VANGUARD FIDUCIARY TRUST CONEW | +1,058,087 | $40.73M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
Fairmount Funds Management LLC↓ DEC | -3,500,000 | $211.83M |
RTW INVESTMENTS, LP↓ DEC | -2,133,566 | $210.10M |
Vivo Capital, LLC↓ DEC | -1,976,693 | $16.25M |
Vestal Point Capital, LP↓ DEC | -1,849,112 | $47.38M |
FRANKLIN RESOURCES INC↓ DEC | -1,302,078 | $937.35K |
TCG Crossover Management, LLC↓ DEC | -921,268 | $190.41M |
Redmile Group, LLC↓ DEC | -749,882 | $26.48M |
Saturn V Capital Management LP↓ DEC | -590,429 | $24.12M |
BALYASNY ASSET MANAGEMENT L.P.↓ DEC | -583,720 | $32.97M |
BARCLAYS PLC↓ DEC | -290,345 | $1.20M |