第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
MPM BioImpact LLCCIK 0001687078 | 10,679,391 | $27.98M | – | no_change |
Deep Track Capital, LPCIK 0001856083 | 7,419,355 | $19.44M | – | no_change |
Nextech Invest, Ltd.CIK 0001595430 | 7,419,355 | $19.44M | – | no_change |
Soleus Capital Management, L.P.CIK 0001802630 | 6,963,141 | $18.24M | +6,963,141 | NEW |
Octagon Capital Advisors LPCIK 0001839435 | 5,250,000 | $13.76M | +5,250,000 | NEW |
Blue Owl Capital Holdings LPCIK 0001858703 | 5,089,015 | $13.33M | -2,343,891 | ↓ DEC |
Avidity Partners Management LPCIK 0001791827 | 4,998,267 | $11.80M | -506,588 | ↓ DEC |
FRANKLIN RESOURCES INCCIK 0000038777 | 3,803,338 | $9.96M | -200,042 | ↓ DEC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 3,431,953 | $8.99M | +3,431,953 | NEW |
MARSHALL WACE, LLPCIK 0001318757 | 2,948,441 | $7.72M | +355,243 | ↑ INC |
TCG Crossover Management, LLCCIK 0001839948 | 2,682,696 | $7.03M | +2,682,696 | NEW |
GREAT POINT PARTNERS LLCCIK 0001281446 | 2,238,496 | $5.86M | -2,445,215 | ↓ DEC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 1,424,374 | $3.73M | -1,176,842 | ↓ DEC |
Squadron Capital Management LLCCIK 0002050709 | 1,100,000 | $2.88M | +1,100,000 | NEW |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 1,093,894 | $2.87M | +1,071,927 | ↑ INC |
Sio Capital Management, LLCCIK 0001482416 | 917,922 | $2.40M | -423,714 | ↓ DEC |
BlackRock, Inc.CIK 0002012383 | 846,696 | $2.22M | -1,350 | ↓ DEC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 603,767 | $1.58M | -4,695 | ↓ DEC |
Cormorant Asset Management, LPCIK 0001583977 | 529,550 | $1.39M | +529,550 | NEW |
JANE STREET GROUP, LLCCIK 0001595888 | 436,931 | $1.14M | +409,536 | ↑ INC |
ADAR1 Capital Management, LLCCIK 0001940272 | 351,094 | $919.87K | – | no_change |
VANGUARD FIDUCIARY TRUST COCIK 0000933478 | 341,344 | $894.32K | +341,344 | NEW |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 287,299 | $752.72K | +287,299 | NEW |
Woodline Partners LPCIK 0001784547 | 250,088 | $655.23K | -430,100 | ↓ DEC |
STATE STREET CORPCIK 0000093751 | 233,507 | $611.79K | +67,900 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
Soleus Capital Management, L.P.NEW | +6,963,141 | $18.24M |
Octagon Capital Advisors LPNEW | +5,250,000 | $13.76M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +3,431,953 | $8.99M |
TCG Crossover Management, LLCNEW | +2,682,696 | $7.03M |
Squadron Capital Management LLCNEW | +1,100,000 | $2.88M |
SUSQUEHANNA INTERNATIONAL GROUP, LLP↑ INC | +1,071,927 | $2.87M |
Cormorant Asset Management, LPNEW | +529,550 | $1.39M |
JANE STREET GROUP, LLC↑ INC | +409,536 | $1.14M |
MARSHALL WACE, LLP↑ INC | +355,243 | $7.72M |
VANGUARD FIDUCIARY TRUST CONEW | +341,344 | $894.32K |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
GREAT POINT PARTNERS LLC↓ DEC | -2,445,215 | $5.86M |
Blue Owl Capital Holdings LP↓ DEC | -2,343,891 | $13.33M |
MILLENNIUM MANAGEMENT LLC↓ DEC | -1,176,842 | $3.73M |
Avidity Partners Management LP↓ DEC | -506,588 | $11.80M |
Woodline Partners LP↓ DEC | -430,100 | $655.23K |
Sio Capital Management, LLC↓ DEC | -423,714 | $2.40M |
RENAISSANCE TECHNOLOGIES LLC↓ DEC | -325,330 | $479.46K |
FRANKLIN RESOURCES INC↓ DEC | -200,042 | $9.96M |
Qube Research & Technologies Ltd↓ DEC | -70,713 | $29.86K |
OSAIC HOLDINGS, INC.↓ DEC | -15,000 | $27.51K |