第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
a16z Capital Management, L.L.C.CIK 0001540358 | 3,233,170 | $56.55M | – | no_change |
Cormorant Asset Management, LPCIK 0001583977 | 2,890,605 | $50.56M | +850,000 | ↑ INC |
Sofinnova Investments, Inc.CIK 0001631134 | 2,293,788 | $40.12M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 2,267,756 | $39.66M | +740,215 | ↑ INC |
Octagon Capital Advisors LPCIK 0001839435 | 1,748,000 | $30.57M | +150,000 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 1,354,906 | $23.70M | +1,354,906 | NEW |
BALYASNY ASSET MANAGEMENT L.P.CIK 0001218710 | 1,327,545 | $23.22M | +1,207,545 | ↑ INC |
BRAIDWELL LPCIK 0001920938 | 1,200,587 | $21.00M | +1,200,587 | NEW |
STATE STREET CORPCIK 0000093751 | 850,894 | $14.88M | +428,048 | ↑ INC |
Sands Capital Alternatives, LLCCIK 0001846444 | 786,353 | $13.75M | – | no_change |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 749,266 | $13.11M | +157,889 | ↑ INC |
ORBIMED ADVISORS LLCCIK 0001055951 | 711,811 | $12.45M | -79,090 | ↓ DEC |
Pivotal bioVenture Partners Investment Advisor LLCCIK 0001844645 | 653,374 | $11.43M | – | no_change |
Cosmic Management, LLCCIK 0002113747 | 501,833 | $8.78M | – | no_change |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 430,463 | $7.53M | +202,049 | ↑ INC |
JACOBS LEVY EQUITY MANAGEMENT, INCCIK 0000884414 | 420,123 | $7.35M | +85,997 | ↑ INC |
STEMPOINT CAPITAL LPCIK 0001952142 | 338,654 | $5.92M | +338,654 | NEW |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 286,946 | $5.02M | +286,946 | NEW |
Comprehensive Financial Management LLCCIK 0001799802 | 271,842 | $4.75M | – | no_change |
FRANKLIN RESOURCES INCCIK 0000038777 | 265,373 | $4.64M | +265,373 | NEW |
MORGAN STANLEYCIK 0000895421 | 259,869 | $4.55M | -51,790 | ↓ DEC |
CHARLES SCHWAB INVESTMENT MANAGEMENT INCCIK 0000884546 | 247,276 | $4.32M | +27,434 | ↑ INC |
NORTHERN TRUST CORPCIK 0000073124 | 224,129 | $3.92M | +56,677 | ↑ INC |
DIMENSIONAL FUND ADVISORS LPCIK 0000354204 | 214,546 | $3.75M | +214,546 | NEW |
Y-Intercept (Hong Kong) LtdCIK 0001772875 | 201,337 | $3.52M | +201,337 | NEW |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +1,354,906 | $23.70M |
BALYASNY ASSET MANAGEMENT L.P.↑ INC | +1,207,545 | $23.22M |
BRAIDWELL LPNEW | +1,200,587 | $21.00M |
Cormorant Asset Management, LP↑ INC | +850,000 | $50.56M |
BlackRock, Inc.↑ INC | +740,215 | $39.66M |
STATE STREET CORP↑ INC | +428,048 | $14.88M |
STEMPOINT CAPITAL LPNEW | +338,654 | $5.92M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +286,946 | $5.02M |
FRANKLIN RESOURCES INCNEW | +265,373 | $4.64M |
DIMENSIONAL FUND ADVISORS LPNEW | +214,546 | $3.75M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
ALLIANCEBERNSTEIN L.P.↓ DEC | -965,315 | $383.67K |
DIADEMA PARTNERS LP↓ DEC | -233,764 | $1.05M |
CITADEL ADVISORS LLC↓ DEC | -213,343 | $300.83K |
SPHERA FUNDS MANAGEMENT LTD.↓ DEC | -156,517 | $1.51M |
ALGERT GLOBAL LLC↓ DEC | -131,822 | $1.12K |
BANK OF AMERICA CORP /DE/↓ DEC | -127,175 | $1.08M |
BNP PARIBAS FINANCIAL MARKETS↓ DEC | -80,231 | $551.95K |
ORBIMED ADVISORS LLC↓ DEC | -79,090 | $12.45M |
Alyeska Investment Group, L.P.↓ DEC | -75,000 | $1.31M |
Persistent Asset Partners Ltd↓ DEC | -57,607 | $265.27K |