第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
BlackRock, Inc.CIK 0002012383 | 22,650,988 | $215.64M | +1,513,197 | ↑ INC |
DEERFIELD MANAGEMENT COMPANY, L.P.CIK 0001009258 | 15,038,000 | $143.16M | +697,000 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 12,208,360 | $116.22M | +1,135,149 | ↑ INC |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 11,244,625 | $107.05M | +11,244,625 | NEW |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 11,135,762 | $106.01M | +11,135,762 | NEW |
TCG Crossover Management, LLCCIK 0001839948 | 11,020,968 | $104.92M | +11,020,968 | NEW |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 7,434,033 | $70.77M | +4,271,504 | ↑ INC |
Vestal Point Capital, LPCIK 0001974915 | 7,025,000 | $66.88M | +4,775,000 | ↑ INC |
TWO SIGMA INVESTMENTS, LPCIK 0001179392 | 6,392,628 | $60.86M | +1,877,311 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 5,782,776 | $55.06M | +728,990 | ↑ INC |
BANK OF AMERICA CORP /DE/CIK 0000070858 | 5,091,765 | $48.47M | +3,556,208 | ↑ INC |
Aberdeen Group plcCIK 0001716774 | 5,040,670 | $47.99M | +4,127,077 | ↑ INC |
UBS Group AGCIK 0001610520 | 4,943,994 | $47.07M | -327,920 | ↓ DEC |
Frazier Life Sciences Management, L.P.CIK 0001892134 | 4,009,240 | $38.17M | +4,009,240 | NEW |
Royalty Pharma Sub-Manager, LLCCIK 0002081668 | 3,846,154 | $36.62M | – | no_change |
Nuveen, LLCCIK 0001871926 | 3,819,263 | $36.36M | +206,897 | ↑ INC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 3,151,704 | $30.00M | +1,823,311 | ↑ INC |
Eversept Partners, LPCIK 0001697013 | 3,039,820 | $28.94M | +46,925 | ↑ INC |
RFG Advisory, LLCCIK 0001633387 | 2,870,700 | $27.33M | +2,870,700 | NEW |
Fisher Asset Management, LLCCIK 0000850529 | 2,733,253 | $26.02M | +265,686 | ↑ INC |
DIMENSIONAL FUND ADVISORS LPCIK 0000354204 | 2,690,651 | $25.61M | +1,461,799 | ↑ INC |
CHARLES SCHWAB INVESTMENT MANAGEMENT INCCIK 0000884546 | 2,350,405 | $22.38M | +345,466 | ↑ INC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 2,347,443 | $22.35M | -865,342 | ↓ DEC |
Candriam S.C.A.CIK 0001537014 | 2,286,841 | $21.77M | +2,286,841 | NEW |
RICE HALL JAMES & ASSOCIATES, LLCCIK 0001230765 | 2,230,105 | $21.23M | +325,959 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +11,244,625 | $107.05M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +11,135,762 | $106.01M |
TCG Crossover Management, LLCNEW | +11,020,968 | $104.92M |
Vestal Point Capital, LP↑ INC | +4,775,000 | $66.88M |
PERCEPTIVE ADVISORS LLC↑ INC | +4,271,504 | $70.77M |
Aberdeen Group plc↑ INC | +4,127,077 | $47.99M |
Frazier Life Sciences Management, L.P.NEW | +4,009,240 | $38.17M |
BANK OF AMERICA CORP /DE/↑ INC | +3,556,208 | $48.47M |
RFG Advisory, LLCNEW | +2,870,700 | $27.33M |
Candriam S.C.A.NEW | +2,286,841 | $21.77M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
Squarepoint Ops LLC↓ DEC | -1,619,427 | $378.56K |
RENAISSANCE TECHNOLOGIES LLC↓ DEC | -1,351,831 | $7.40M |
BNP PARIBAS FINANCIAL MARKETS↓ DEC | -1,240,457 | $12.40M |
Elmind Capital, LP↓ DEC | -1,150,000 | $9.52M |
GOLDMAN SACHS GROUP INC↓ DEC | -865,342 | $22.35M |
Jump Financial, LLC↓ DEC | -801,521 | $1.04M |
BARCLAYS PLC↓ DEC | -592,770 | $1.27M |
Hudson Bay Capital Management LP↓ DEC | -527,005 | $4.67M |
MARSHALL WACE, LLP↓ DEC | -484,934 | $2.35M |
Susquehanna Portfolio Strategies, LLC↓ DEC | -404,505 | $3.56M |