第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
Siren, L.L.C.CIK 0002005245 | 5,802,970 | $115.42M | +586,001 | ↑ INC |
Vestal Point Capital, LPCIK 0001974915 | 5,425,000 | $107.90M | +1,850,000 | ↑ INC |
Deep Track Capital, LPCIK 0001856083 | 4,062,500 | $80.80M | +1,448,496 | ↑ INC |
Red Tree Management, LLCCIK 0002055980 | 3,170,509 | $63.06M | – | no_change |
TPG GP A, LLCCIK 0001903793 | 3,010,425 | $59.88M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 2,843,707 | $56.56M | +315,256 | ↑ INC |
Omega Fund Management, LLCCIK 0001637359 | 2,392,150 | $47.58M | +187,500 | ↑ INC |
Royalty Pharma Sub-Manager, LLCCIK 0002081668 | 2,388,150 | $46.69M | +1,125,000 | ↑ INC |
FMR LLCCIK 0000315066 | 2,100,929 | $41.79M | -1,246,294 | ↓ DEC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 1,774,220 | $35.29M | +1,774,220 | NEW |
CITADEL ADVISORS LLCCIK 0001423053 | 1,726,242 | $34.33M | +929,384 | ↑ INC |
FRANKLIN RESOURCES INCCIK 0000038777 | 1,621,643 | $32.25M | +1,618 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 1,419,388 | $28.23M | -230,149 | ↓ DEC |
Jones Hill Capital LPCIK 0002102314 | 1,260,136 | $25.06M | +1,260,136 | NEW |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 830,906 | $16.53M | +19,506 | ↑ INC |
FIL LtdCIK 0000318989 | 679,904 | $13.52M | -78,589 | ↓ DEC |
ORBIMED ADVISORS LLCCIK 0001055951 | 667,300 | $13.27M | +458,200 | ↑ INC |
ACORN CAPITAL ADVISORS, LLCCIK 0002054410 | 643,382 | $12.80M | – | no_change |
Aisling Capital Management LPCIK 0001766721 | 568,919 | $11.32M | – | no_change |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 558,964 | $11.12M | +6,633 | ↑ INC |
Palo Alto Investors LPCIK 0001306923 | 550,408 | $10.95M | +251,833 | ↑ INC |
Rock Springs Capital Management LPCIK 0001595725 | 489,095 | $9.73M | +60,000 | ↑ INC |
NAN FUNG TRINITY (HK) LtdCIK 0001781880 | 427,885 | $8.51M | +55,500 | ↑ INC |
DAFNA Capital Management LLCCIK 0001389933 | 421,733 | $8.39M | +160,150 | ↑ INC |
MORGAN STANLEYCIK 0000895421 | 421,219 | $8.38M | +311,763 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
T. Rowe Price Investment Management, Inc.↑ INC | +6,440,537 | $131.39K |
Vestal Point Capital, LP↑ INC | +1,850,000 | $107.90M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +1,774,220 | $35.29M |
Deep Track Capital, LP↑ INC | +1,448,496 | $80.80M |
Jones Hill Capital LPNEW | +1,260,136 | $25.06M |
Royalty Pharma Sub-Manager, LLC↑ INC | +1,125,000 | $46.69M |
Atle Fund Management AB↑ INC | +1,058,271 | $2.32M |
CITADEL ADVISORS LLC↑ INC | +929,384 | $34.33M |
Siren, L.L.C.↑ INC | +586,001 | $115.42M |
ORBIMED ADVISORS LLC↑ INC | +458,200 | $13.27M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
FMR LLC↓ DEC | -1,246,294 | $41.79M |
MILLENNIUM MANAGEMENT LLC↓ DEC | -277,997 | $3.12M |
STATE STREET CORP↓ DEC | -230,149 | $28.23M |
PRICE T ROWE ASSOCIATES INC /MD/↓ DEC | -183,337 | $27.37K |
FIL Ltd↓ DEC | -78,589 | $13.52M |
JANE STREET GROUP, LLC↓ DEC | -77,983 | $541.01K |
BARCLAYS PLC↓ DEC | -74,418 | $573.29K |
CITIGROUP INC↓ DEC | -57,112 | $190.65K |
BNP PARIBAS FINANCIAL MARKETS↓ DEC | -55,505 | $803.48K |
Russell Investments Group, Ltd.↓ DEC | -36,705 | $395.67K |