第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
PFIZER INCCIK 0000078003 | 22,032,040 | $49.79M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 19,091,095 | $46.58M | +1,415,066 | ↑ INC |
TPG GP A, LLCCIK 0001903793 | 18,716,306 | $45.67M | – | no_change |
STATE STREET CORPCIK 0000093751 | 8,660,306 | $21.13M | +5,898,906 | ↑ INC |
PRIMECAP MANAGEMENT CO/CA/CIK 0000763212 | 8,379,840 | $20.45M | +240,000 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 6,921,350 | $16.89M | +6,921,350 | NEW |
CITADEL ADVISORS LLCCIK 0001423053 | 6,887,120 | $16.80M | -5,321,700 | ↓ DEC |
TWO SIGMA INVESTMENTS, LPCIK 0001179392 | 5,375,456 | $13.12M | +1,952,015 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 4,124,178 | $10.07M | +191,268 | ↑ INC |
Frazier Life Sciences Management, L.P.CIK 0001892134 | 3,796,668 | $9.26M | -72,082 | ↓ DEC |
Woodline Partners LPCIK 0001784547 | 3,501,078 | $8.54M | +579 | ↑ INC |
Patient Square Capital LPCIK 0001819257 | 3,450,000 | $8.42M | -1,513,756 | ↓ DEC |
MARSHALL WACE, LLPCIK 0001318757 | 3,447,984 | $8.41M | +3,162,423 | ↑ INC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 3,322,053 | $8.11M | +1,480,746 | ↑ INC |
Candriam S.C.A.CIK 0001537014 | 2,997,318 | $7.31M | +691,674 | ↑ INC |
Wildcat Capital Management, LLCCIK 0001582384 | 2,920,787 | $7.13M | – | no_change |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 2,766,244 | $6.75M | +476,786 | ↑ INC |
Boxer Capital Management, LLCCIK 0002018299 | 2,725,000 | $6.65M | +2,725,000 | NEW |
AQR CAPITAL MANAGEMENT LLCCIK 0001167557 | 2,484,780 | $6.06M | +1,055,533 | ↑ INC |
Nuveen, LLCCIK 0001871926 | 2,315,092 | $5.65M | +2,043,085 | ↑ INC |
MPM BioImpact LLCCIK 0001687078 | 2,242,933 | $5.47M | +2,242,933 | NEW |
RENAISSANCE TECHNOLOGIES LLCCIK 0001037389 | 2,139,328 | $5.22M | -47,756 | ↓ DEC |
BANK OF AMERICA CORP /DE/CIK 0000070858 | 2,134,473 | $5.21M | +1,127,145 | ↑ INC |
JACOBS LEVY EQUITY MANAGEMENT, INCCIK 0000884414 | 2,013,508 | $4.91M | +1,134,553 | ↑ INC |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 1,694,112 | $4.13M | +1,694,112 | NEW |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +6,921,350 | $16.89M |
STATE STREET CORP↑ INC | +5,898,906 | $21.13M |
MARSHALL WACE, LLP↑ INC | +3,162,423 | $8.41M |
Boxer Capital Management, LLCNEW | +2,725,000 | $6.65M |
MPM BioImpact LLCNEW | +2,242,933 | $5.47M |
PRICE T ROWE ASSOCIATES INC /MD/↑ INC | +2,171,627 | $13.13K |
Nuveen, LLC↑ INC | +2,043,085 | $5.65M |
TWO SIGMA INVESTMENTS, LP↑ INC | +1,952,015 | $13.12M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +1,694,112 | $4.13M |
MILLENNIUM MANAGEMENT LLC↑ INC | +1,480,746 | $8.11M |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
CITADEL ADVISORS LLC↓ DEC | -5,321,700 | $16.80M |
JANE STREET GROUP, LLC↓ DEC | -1,639,210 | $1.31M |
ExodusPoint Capital Management, LP↓ DEC | -1,570,525 | $156.92K |
Patient Square Capital LP↓ DEC | -1,513,756 | $8.42M |
ACADIAN ASSET MANAGEMENT LLC↓ DEC | -906,522 | $214.00 |
BNP PARIBAS FINANCIAL MARKETS↓ DEC | -829,459 | $173.16K |
Aberdeen Group plc↓ DEC | -624,113 | $3.57M |
BARCLAYS PLC↓ DEC | -481,841 | $392.46K |
GSA CAPITAL PARTNERS LLP↓ DEC | -462,276 | $370.00 |
Man Group plc↓ DEC | -371,423 | $377.43K |